CAS 71320-77-9
:Moclobemide
Description:
Moclobemide is a reversible inhibitor of monoamine oxidase A (RIMA) primarily used as an antidepressant. It is classified as an aromatic amine and is known for its selective action on the monoamine oxidase enzyme, which plays a crucial role in the metabolism of neurotransmitters such as serotonin, norepinephrine, and dopamine. This selectivity allows moclobemide to enhance mood and alleviate symptoms of depression with a lower risk of dietary restrictions compared to irreversible MAO inhibitors. The substance is typically administered orally and is well-absorbed in the gastrointestinal tract. Moclobemide has a relatively short half-life, necessitating multiple daily doses for optimal therapeutic effect. Common side effects may include insomnia, dizziness, and gastrointestinal disturbances. Its pharmacokinetics involve extensive hepatic metabolism, and it is primarily excreted in urine. Due to its mechanism of action, moclobemide is also explored for use in anxiety disorders and social phobia, making it a versatile option in psychiatric treatment.
Formula:C13H17ClN2O2
InChI:InChI=1S/C13H17ClN2O2/c14-12-3-1-11(2-4-12)13(17)15-5-6-16-7-9-18-10-8-16/h1-4H,5-10H2,(H,15,17)
InChI key:InChIKey=YHXISWVBGDMDLQ-UHFFFAOYSA-N
SMILES:C(NCCN1CCOCC1)(=O)C2=CC=C(Cl)C=C2
Synonyms:- 4-Chloro-N-(2-morpholin-4-ylethyl)benzamide
- 4-Chloro-N-(2-morpholinoethyl)benzamide
- 4-Chloro-N-[2-(4-morpholinyl)ethyl]benzamide
- Auromid
- Aurorix
- Manerix
- Moclaime
- Moclobemide
- Ro 11-1163
- Ro 11-1163/000
- p-Chloro-N-(2-morpholinoethyl)-benzamide
- Benzamide, 4-Chloro-N-(2-(4-morpholinyl)ethyl)-
- Benzamide, 4-chloro-N-[2-(4-morpholinyl)ethyl]-
- benzamide, 4-chloro-N-[2-(4-morpholinyl)ethyl]-
- See more synonyms
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Moclobemide
CAS:Formula:C13H17ClN2O2Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:268.74Moclobemide
CAS:Moclobemide (Ro111163) is a reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.Formula:C13H17ClN2O2Purity:99.51% - 99.59%Color and Shape:White To Off-White SolidMolecular weight:268.739Moclobemide-d4
CAS:Formula:C13H13D4ClN2O2Color and Shape:White To Off-White SolidMolecular weight:272.77Moclobemide 1.0 mg/ml in Methanol
CAS:Formula:C13H17ClN2O2Color and Shape:ColourlessMolecular weight:268.74Moclobemide (Standard)
CAS:Moclobemide (Standard) is a reference standard for research and analysis in studies involving Moclobemide. Moclobemide (Ro111163) is a reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties.Formula:C13H17ClN2O2Color and Shape:SolidMolecular weight:268.739Moclobemide 1.0 mg/ml in Methanol
CAS:Formula:C13H17ClN2O2Color and Shape:White To Off-WhiteMolecular weight:268.74Moclobemide
CAS:Controlled ProductApplications A reversible monoamine oxidase inhibitor.
References Wiesel, F.A., et al.: Eur. J. Clin. Pharmacol., 28, 89 (1985), Burkard, W.P., et al.: J. Pharmacol. Exp. Ther., 248, 391 (1989)Formula:C13H17ClN2O2Color and Shape:NeatMolecular weight:268.74Moclobemide-d8
CAS:Controlled ProductApplications Moclobemide-d8 is the labeled analogue of Moclobemide (M481000), a reversible monoamine oxidase inhibitor.
References Wiesel, F.A., et al.: Eur. J. Clin. Pharmacol., 28, 89 (1985), Burkard, W.P., et al.: J. Pharmacol. Exp. Ther., 248, 391 (1989)Formula:C13H9D8ClN2O2Color and Shape:NeatMolecular weight:276.79Moclobemide
CAS:4-Chloro-N-(2-morpholinoethyl)benzamideFormula:C13H17ClN2O2Purity:99%Molecular weight:268.74Moclobemide - Bio-X ™
CAS:Controlled ProductMoclobemide is a monoamine oxidase inhibitor that is used to treat major depressive disorder and dipolar disorder. This drug’s mechanism of action involves the reversible inhibition of the enzyme MAO-A. The inhibition of this enzyme results in a decreased metabolism and destruction of neurotransmitters thus relieving the symptoms of depression and bipolar disorder.Formula:C13H17ClN2O2Purity:(%) Min. 95%Color and Shape:PowderMolecular weight:268.74 g/mol
