CAS 71989-38-3

Fmoc-L-Tyr(tBu)-OH

Description:

Fmoc-L-Tyr(tBu)-OH, also known as 9-fluorenylmethoxycarbonyl-L-tyrosine (tert-butyl), is a protected form of the amino acid tyrosine, commonly used in peptide synthesis. The Fmoc group serves as a protective group for the amino functionality, allowing for selective reactions without interfering with the amino acid's side chain. The tert-butyl (tBu) group protects the hydroxyl group of the tyrosine side chain, enhancing the stability and solubility of the compound during synthesis. This compound is typically a white to off-white solid and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane, but less soluble in water. Its molecular structure includes a fluorenyl ring, which contributes to its stability and ease of removal under mild conditions during deprotection steps in peptide synthesis. Fmoc-L-Tyr(tBu)-OH is widely utilized in the field of organic chemistry and biochemistry for the synthesis of peptides and proteins, facilitating the introduction of tyrosine residues into larger molecular constructs.

Formula: C₂₈H₂₉NO₅

InChI: InChI=1/C28H29NO5/c1-28(2,3)34-19-14-12-18(13-15-19)16-25(26(30)31)29-27(32)33-17-24-22-10-6-4-8-20(22)21-9-5-7-11-23(21)24/h4-15,24-25H,16-17H2,1-3H3,(H,29,32)(H,30,31)

InChI key: InChIKey=JAUKCFULLJFBFN-VWLOTQADSA-N

SMILES: C(OC(N[C@@H](CC1=CC=C(OC(C)(C)C)C=C1)C(O)=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Synonyms:

• (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid
• (2S)-3-[4-(tert-Butoxy)phenyl]-2-([[(9H-fluoren-9-yl)methoxy]carbonyl]amino)propanoic acid
• (S)-3-(4-tert-Butoxyphenyl)-2-[[[(9H-fluoren-9-yl)methoxy]carbonyl]amino]propionic acid
• <span class="text-smallcaps">L</span>-Tyrosine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-L-Tyr(tBu)-OH
• Fmoc-Tyr(But)-OH
• Fmoc-Tyr(OtBu)-OH
• Fmoc-Tyr(tBu)-OH
• N-(9-Fluorenyl Methoxy Carbonyl)-O-Tertbutyl-L-Tyrosine
• N-alpha-(9-fluorenylmethyloxycarbonyl)-O-t-butyl-L-tyrosine
• N-fmoc-O-T-butyl-L-tyrosine
• NSC 334301
• O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-tyrosine
• O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]tyrosine
• Tyr(tBu)
• O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tyrosine
• L-Tyrosine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-O-tert.butyl-L-tyrosine
• FMOC-L-TYR(T-BU)
• N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-TERT-BUTYL-L-TYROSINE
• N-(9-FLUORENYLMETHOXYCARBONYL)-O-TERT-BUTYL-L-TYROSINE
• FMOC-L-TYR(O-T-BUTYL)
• FMOC-O-T-BUTYL-L-TYROSINE
• FMOC-TYR(BUT)
• FMOC-TYR(TRT)-OH
• N-9-FLUORENYLMETHYLOXYCARBONYL-O-T-BUTYL-L-TYROSINE
• FMOC-L-TYROSINE(O-T-BUTYL)
• FMOC-L-TYROSINE (TBU)
• FMOC-TYR(TBU)
• N-9-FLUORENYLMETHYLOXYCARBONYL-O-TERT-BUTYL-L-TYROSINE
• FMOC-TYROSINE(TBU)-OH
• 9-FLUORENYLMETHOXYCARBONYL-O-T-BUTYL-L-TYROSINE

N-Fmoc-O-tert-butyl-L-tyrosine, 98%

CAS: 71989-38-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₈H₂₉NO₅

Purity: 98%

Molecular weight: 459.54

Ref: 02-H59730

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

Bachem ID: 4093144.

Formula: C₂₈H₂₉NO₅

Purity: 99.8%

Color and Shape: White

Molecular weight: 459.54

Ref: 01-4093144

Fmoc-O-tert-butyl-L-tyrosine

CAS: 71989-38-3

Formula: C₂₈H₂₉NO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 459.5336

Ref: IN-DA0034Y7

Fmoc-L-Tyr(tBu)-OH

CAS: 71989-38-3

Fmoc-L-Tyr(tBu)-OH

Formula: C₂₈H₂₉NO₅

Purity: >98%

Color and Shape: Solid-Powder

Molecular weight: 459.53355

Ref: 54-BI467

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

Formula: C₂₈H₂₉NO₅

Purity: ≥ 99.0%

Color and Shape: White to almost white powder

Molecular weight: 459.53

Ref: 7W-GM6164

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

Fmoc-Tyr(tBu)-OH is a protected amino acid for solid-phase peptide synthesis, enabling Leu-EnkephalinAmide formation and versatile amino acid derivatives.

Formula: C₂₈H₂₉NO₅

Purity: 99.89%

Color and Shape: White Solid

Molecular weight: 459.54

Ref: TM-T67575

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-tert-butyl-L-tyrosine

CAS: 71989-38-3

Formula: C₂₈H₂₉NO₅

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 459.54

Ref: 3B-F0506

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

Fmoc-Tyr(tBu)-OH

Formula: C₂₈H₂₉NO₅

Purity: 98%

Molecular weight: 459.53

Ref: IN-DG8611

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

Fmoc-Tyr(tBu)-OH is an amide that binds to the natriuretic receptor. It has a disulfide bond with a hydroxyapatite, which makes it more stable and inhibits its degradation. Fmoc-Tyr(tBu)-OH is hemolytic in vitro and minimally toxic in vivo at high concentrations. It also has a hydroxyl group, which can be used to synthesize other molecules. Fmoc-Tyr(tBu)-OH also has antimicrobial properties, as it inhibits the growth of bacteria and fungi by binding to cell membranes and disrupting their integrity.br>br> Fmoc-Tyr(tBu)-OH is taken up by cells through sodium/hydrogen antiporter system. This uptake process is mediated by the protein Na+, K+ -ATPase, which provides energy for transport across the membrane.

Formula: C₂₈H₂₉NO₅

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 459.53 g/mol

Ref: 3D-FF15877

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

Fmoc-Tyr(tBu)-OH is a building block for the synthesis of peptides. It is reacted with tert-butyl alcohol and hydrochloric acid to produce the corresponding Fmoc-protected tyrosine. The Fmoc group can be removed by treatment with dicyclohexylcarbodiimide and tert-butyl alcohol, followed by saponification in aqueous base. The morphologies of the resulting free amino acids are determined by their solubility in organic solvents such as chloroform or ethyl acetate, as well as in water.

Formula: C₂₈H₂₉NO₅

Purity: Min. 98.0 Area-%

Molecular weight: 459.53 g/mol

Ref: 3D-FLY-1737-PI

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

M03428 - Fmoc-Tyr(tBu)-OH

Formula: C₂₈H₂₉NO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 459.542

Ref: 10-M03428

FMOC-O-Tert-Butyl-L-Tyrosine (FMOC-Tyr(tBu)-OH) extrapure, 98%

CAS: 71989-38-3

Formula: C₂₈H₂₉NO₅

Purity: min. 98%

Color and Shape: White, Crystalline powder

Molecular weight: 459.53

Ref: SR-22292

Fmoc-L-Tyr(tBu)-OH

Controlled Product

CAS: 71989-38-3

Applications Fmoc-L-Tyr(tBu)-OH is tyrosine derivative used in soiid phase peptide synthesis.
References Atherton, E., et al.: J. Chem. Soc. Chem. Comm., 20, 970 (1980);

Formula: C₂₈H₂₉NO₅

Color and Shape: Neat

Molecular weight: 459.53

Ref: TR-F622860