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CAS 72-14-0

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Sulfathiazole

Description:
Sulfathiazole is a sulfonamide antibiotic that belongs to the class of compounds known as sulfa drugs. It is characterized by its thiazole ring structure, which is fused to a sulfanilamide moiety. This compound exhibits antibacterial properties by inhibiting bacterial folic acid synthesis, thereby interfering with the growth and reproduction of bacteria. Sulfathiazole is typically used in the treatment of various bacterial infections, particularly those caused by Gram-positive organisms. It is soluble in water and has a relatively low melting point, which facilitates its use in pharmaceutical formulations. The compound is often administered orally or topically, depending on the type of infection being treated. However, its use has declined with the advent of more effective antibiotics and concerns regarding resistance. Sulfathiazole may also have side effects, including allergic reactions and gastrointestinal disturbances. Overall, it remains an important historical compound in the development of antimicrobial therapies.
Formula:C9H9N3O2S2
InChI:InChI=1S/C9H9N3O2S2/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9/h1-6H,10H2,(H,11,12)
InChI key:InChIKey=JNMRHUJNCSQMMB-UHFFFAOYSA-N
SMILES:S(NC1=NC=CS1)(=O)(=O)C2=CC=C(N)C=C2
Synonyms:
  • 2-(P-Aminobenzenesulfonamido)Thiazole
  • 2-(Sulfanilylamino)thiazole
  • 2-(p-Aminobenzenesulphonamido)thiazole
  • 2-Sulfanilamidothiazole
  • 2-Sulfathiazole
  • 2090 R.P.
  • 4-Amino-N-2-Thiazolyl-Benzenesulfonamide
  • 4-Amino-N-2-thiazolylbenzenesulfonamide
  • 4-Amino-N-2-thiazolylbenzensulfonamide
  • 4-[(1,3-Thiazol-2-yl)aminosulfonyl]aniline
  • See more synonyms
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