CAS: 72496-41-4 - Pirarubicin

Formula: C₃₂H₃₇NO₁₂

InChI: InChI=1S/C32H37NO12/c1-14-31(45-21-8-3-4-9-42-21)17(33)10-22(43-14)44-19-12-32(40,20(35)13-34)11-16-24(19)30(39)26-25(28(16)37)27(36)15-6-5-7-18(41-2)23(15)29(26)38/h5-7,14,17,19,21-22,31,34,37,39-40H,3-4,8-13,33H2,1-2H3/t14-,17-,19-,21+,22-,31+,32-/m0/s1

InChI key: InChIKey=KMSKQZKKOZQFFG-YXRRJAAWSA-N

SMILES: O=C1C=2C=CC=C(OC)C2C(=O)C=3C(O)=C4C(=C(O)C13)CC(O)(C(=O)CO)CC4OC5OC(C)C(OC6OCCCC6)C(N)C5

Synonyms:

• (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-4-O-[(2S)-tetrahydro-2H-pyran-2-yl]-alpha-L-lyxo-hexopyranoside
• (2''R)-4'-O-Tetrahydropyranyladriamycin
• (2′′R)-4′-O-Tetrahydropyranyladriamycin
• (2′′R)-4′-O-Tetrahydropyranyldoxorubicin
• (3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-alpha-L-lyxo-hexopyranoside
• (8S,10S)-10-((3-Amino-2,3,6-trideoxy-4-O-(2R-tetrahydro-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)oxy)-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione
• (8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-<span class="text-smallcaps">L</span>-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
• 1609Rb
• 4'-O-Tetrahydropyranyladriamycin
• 4'-O-Tetrahydropyranyldoxorubicin
• 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-
• 5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-α-<span class="text-smallcaps">L</span>-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, [8S-[8α,10α(S*)]]-
• 5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-<span class="text-smallcaps">L</span>-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (8S,10S)-
• 5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-<span class="text-smallcaps">L</span>-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-
• Pinorubicin
• Pirarubicin Hydrochloride
• Pirarubicin [INN:JAN]
• Pirarubicina
• Pirarubicina [Spanish]
• Pirarubicine
• Pirarubicine [French]
• Pirarubicinum
• Pirarubicinum [Latin]
• THP-adriamycin
• Therarubicin

Pirarubicin

CAS: 72496-41-4

• Formula: C₃₂H₃₇NO₁₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 627.6357

Pirarubicin

CAS: 72496-41-4

• Formula: C₃₂H₃₇NO₁₂
• Purity: ≥ 95%
• Color and Shape: Red to orange powder
• Molecular weight: 627.64

Doxorubicin Impurity 45 (Pirarubicin) HCl

CAS: 72496-41-495343-20-7

• Formula: C₃₂H₃₇NO₁₂·HCl
• Molecular weight: 627.64 36.46

Pirarubicin

CAS: 72496-41-4

Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.

• Formula: C₃₂H₃₇NO₁₂
• Purity: 97.61% - 98.66%
• Color and Shape: Red Crystalline Powder
• Molecular weight: 627.64

Pirarubicin

CAS: 72496-41-4

Antibiotic of anthracycline class; DNA synthesis inhibitor

• Formula: C₃₂H₃₇NO₁₂
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 627.64 g/mol

Pirarubicin

CAS: 72496-41-4

Applications Structural analog of Doxorubicin. Antineoplastic. References Umezawa, H., et al.: J. Antibiot., 32, 1082 …

• Formula: C₃₂H₃₇NO₁₂
• Color and Shape: Neat
• Molecular weight: 627.64