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CAS 74011-58-8

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Enoxacin

Description:
Enoxacin is a synthetic antibiotic belonging to the fluoroquinolone class, primarily used to treat bacterial infections. Its chemical structure features a bicyclic core that includes a quinolone moiety, which is essential for its antibacterial activity. Enoxacin exhibits broad-spectrum activity against various Gram-negative and some Gram-positive bacteria by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes crucial for DNA replication and transcription. The substance is typically administered orally and is well-absorbed in the gastrointestinal tract. Enoxacin is known for its relatively low toxicity profile, although it can cause side effects such as gastrointestinal disturbances, central nervous system effects, and potential tendon damage. It is important to note that the use of fluoroquinolones, including enoxacin, has been associated with an increased risk of serious side effects, leading to more cautious prescribing practices. As with all antibiotics, appropriate use is critical to prevent the development of antibiotic resistance.
Formula:C15H17FN4O3
InChI:InChI=1/C15H17FN4O3.H2O/c1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)19)20-5-3-17-4-6-20;/h7-8,17H,2-6H2,1H3,(H,22,23);1H2
InChI key:InChIKey=IDYZIJYBMGIQMJ-UHFFFAOYSA-N
SMILES:C(C)N1C=2C(C(=O)C(C(O)=O)=C1)=CC(F)=C(N2)N3CCNCC3
Synonyms:
  • 1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-
  • 1-Ethyl-6-Fluoro-4-Oxo-7-(Piperazin-1-Yl)-1,4-Dihydro-1,8-Naphthyridine-3-Carboxylic Acid
  • 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic Acid
  • 1-Ethyl-6-fluoro-4-oxo-7-piperazin-4-ium-1-yl-1,8-naphthyridine-3-carboxylate
  • At 2266
  • Ci 919
  • Enofloxacin
  • Enofloxacine
  • Enoksetin
  • Enoxacin (Patent-No-Supply)
  • See more synonyms
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