CAS 75184-71-3: Albendazole sulfone
Description:Albendazole sulfone is a metabolite of albendazole, an anthelmintic medication used to treat parasitic infections. It is characterized by its chemical structure, which includes a sulfone functional group, contributing to its pharmacological activity. The compound is typically a white to off-white solid and is soluble in organic solvents, with limited solubility in water. Albendazole sulfone exhibits a broad spectrum of activity against various helminths and some protozoa, making it effective in treating conditions like neurocysticercosis and other parasitic diseases. Its mechanism of action involves the inhibition of microtubule polymerization, disrupting the cytoskeleton of the parasites. The compound is generally well-tolerated, but like many medications, it may have side effects, including gastrointestinal disturbances. In terms of safety, it is important to consider its pharmacokinetics, including absorption, distribution, metabolism, and excretion, which can vary based on individual patient factors. Overall, albendazole sulfone plays a significant role in the management of parasitic infections, particularly in regions where such diseases are endemic.
Formula:C12H15N3O4S
InChI:InChI=1S/C12H15N3O4S/c1-3-6-20(17,18)8-4-5-9-10(7-8)14-11(13-9)15-12(16)19-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
InChI key:InChIKey=CLSJYOLYMZNKJB-UHFFFAOYSA-N
SMILES:O=C(OC)NC1=NC=2C=CC(=CC2N1)S(=O)(=O)CCC
- Synonyms:
- 2-Benzimidazolecarbamic acid, 5-(propylsulfonyl)-, methyl ester
- 5-(Propylsulfonyl)-2-benzimidazolecarbamic acid methyl ester
- Carbamic acid, (5-(propylsulfonyl)-1H-benzimidazol-2-yl)-, methyl ester (9CI)
- Carbamic acid, N-[6-(propylsulfonyl)-1H-benzimidazol-2-yl]-, methyl ester
- Carbamic acid, [5-(propylsulfonyl)-1H-benzimidazol-2-yl]-, methyl ester
- Methyl (5-(propylsulfonyl)-1H-benzimidazol-2-yl)carbamate
- Methyl (5-propylsulfonyl)2-benzimidazolecarbamate
- [5-(Propane-1-sulfonyl)-1H-benzoimidazol-2-yl]-carbamic acid methyl ester
- methyl [6-(propylsulfonyl)-1H-benzimidazol-2-yl]carbamate
- Albendazole sulfone
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