CAS 76095-16-4
:Enalapril maleate
Description:
Enalapril maleate is a pharmaceutical compound primarily used as an antihypertensive agent in the treatment of high blood pressure and heart failure. It is an ester derivative of enalapril, which is an angiotensin-converting enzyme (ACE) inhibitor. The maleate salt form enhances the solubility and stability of the drug. Enalapril maleate is typically a white to off-white crystalline powder, with a molecular formula that reflects its complex structure, including both the enalapril and maleate components. It is soluble in water and methanol but has limited solubility in organic solvents. The compound works by inhibiting the ACE enzyme, leading to decreased production of angiotensin II, which results in vasodilation and reduced blood pressure. Common side effects may include dizziness, fatigue, and cough, while serious adverse effects can involve renal impairment and hyperkalemia. Enalapril maleate is usually administered orally and is often prescribed in combination with other antihypertensive medications for enhanced efficacy.
Formula:C24H32N2O9
InChI:InChI=1/C20H28N2O5.C4H4O4/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25;5-3(6)1-2-4(7)8/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25);1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,16?,17-;/m0./s1
SMILES:C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(OCC)=O)C)(=O)N2[C@H](C(O)=O)CCC2.C(=C\C(O)=O)\C(O)=O
Synonyms:- (2S)-1-[(2S)-2-[(1-ethoxycarbonyl-3-phenyl-propyl)amino]propanoyl]pyrrolidine-2-carboxylic acid
- (2S)-1-[2-[(1-ethoxycarbonyl-3-phenyl-propyl)amino]propanoyl]pyrrolidine-2-carboxylic acid
- (S)-1-(N-(1-(Ethoxycarbonyl)-3-Phenylpropyl)-L-Alanyl)-L-Proline (Z)-2-Butenedioate Salt
- <span class="text-smallcaps">L</smallcap>-Proline, 1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-<smallcap>L</span>-alanyl]-, (S)-, (Z)-2-butenedioate (1:1)
- <span class="text-smallcaps">L</smallcap>-Proline, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-<smallcap>L</span>-alanyl-, (2Z)-2-butenedioate (1:1)
- Acapril
- Acetensil
- Alphrin
- Amprace
- Analept
- Antiprex
- Benalipril
- Biocronil
- Bitensil
- But-2-Enedioic Acid
- Cardiovet
- Controlvas
- Converten
- Convertin
- Ednyt
- Elfonal
- Enacard
- Enace
- Enaladil
- Enalapril LPH
- Enaloc
- Enapren
- Enapril
- Enaprin
- Enaril
- Envas
- Ezapril
- Glioten
- Hipoartel
- Hytrol
- Innovace
- Innovade
- Inoprilat
- Invoril
- Kenopril
- Lapril
- Lotrial
- MK 421 maleate
- Minipril
- Mk 421
- Naprilene
- Naritec
- Nuril
- Olivin
- Presil
- Pressotec
- Renavace
- Renitec
- Renitek
- Reniten
- Renivace
- Repantril
- Sintec
- Tenace
- Unaril
- Unipril
- Vasopril
- Vasotec
- Xanef
- L-Proline, 1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-, (S)-, (Z)-2-butenedioate (1:1)
- Enalapril maleate
- L-Proline, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-, (2Z)-2-butenedioate (1:1)
- ENALAPRIL MALEATE, EP STANDARD
- (S)-1-[N-[1-(ETHOXYCARBONXYL)-3-PHENYLPROPYL]-L-ALANYL]-L-PROLINE
- Enalapril maleate BP2000/USP25
- (s)-1-(n-(1-(ethoxycarbonyl)-3-phenylpropyl)-l-alanyl)-l-prolinemaleate(1:1
- Enalapril Maleate USP24,25,EP2000
- ENALAPRIL MALEATE, MM(CRM STANDARD)
- ENALAPRIL MALEATE, IMP. I (EP): 1H-IMIDAZOLE MM(CRM STANDARD)
- 1-[n-[1-(ethoxycarbonyl)-3-phenylpropyl]-l-alanyl]-l-prolin(s)-l-prolin(z)-2-but
- ENALAPRIL MALEATE, IMP. D (EP): ETHYL(2S)-2-[(3S,8AS)-3-METHYL-1,4-DIOXO-OCTAHYDROPYRROLO[1,2-ALPHA]PYRAZIN-2-YL]-4-PHENYLBUTANOATE MM(CRM STANDARD)
- [S]-1-[N-(1-[ETHOXYCARBONYL]-3-PHENYLPROPYL)-6-ALANYL]-L-PROLINE MALEATE
- mk421maleate
- ENALAPRIL MALEATE, USP STANDARD
- N-[[(S)-1-ETHOXYCARBONYL-3-PHENYLPROPYL]-L-ALANYL]-L-PROLINE MALEATE(1: 1)
- See more synonyms
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Enalapril maleate salt
CAS:<p>Long-acting ACE inhibitor and antihypertensive</p>Formula:C20H28N2O5·C4H4O4Molecular weight:492.52ENALAPRIL MALEATE CRS
CAS:<p>ENALAPRIL MALEATE CRS</p>Formula:C24H32N2O9Color and Shape:Crystalline Powder. White. Whitish. Powder.Molecular weight:492.5189ENALAPRIL FOR SYSTEM SUITABILITY CRS
CAS:<p>ENALAPRIL FOR SYSTEM SUITABILITY CRS</p>Formula:C24H32N2O9Molecular weight:492.5189Enalapril maleate
CAS:Enalapril maleateFormula:C20H28N2O5C4H4O4Purity:99.8%Color and Shape:Off WhiteMolecular weight:492.21078Enalapril Maleate
CAS:<p>Cardiovascular drugs, nesoi</p>Formula:C20H28N2O5·C4H4O4Color and Shape:PowderMolecular weight:376.19982L-Proline, 1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-, (S)-, (Z)-2-butenedioate (1:1)
CAS:Formula:C24H32N2O9Purity:98%Color and Shape:SolidMolecular weight:492.5189Enalapril Maleate
CAS:Formula:C20H28N2O5·C4H4O4Color and Shape:White To Off-White SolidMolecular weight:376.46 116.07Enalapril maleate salt
CAS:Formula:C20H28N2O5·C4H4O4Purity:98.5 - 101.5 % (dried basis)Color and Shape:White to off-white powderMolecular weight:492.52Enalapril-d5 Maleate(phenyl-d5)
CAS:Purity:98 atom % DColor and Shape:White-Pale Yellow Solid.Molecular weight:497.56Enalapril maleate
CAS:Controlled ProductFormula:C20H28N2O5·C4H4O4Color and Shape:NeatMolecular weight:492.52Enalapril Maleate
CAS:Formula:C20H28N2O5·C4H4O4Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:492.53Enalapril maleate 100 µg/mL in Acetonitrile
CAS:Formula:C20H28N2O5·C4H4O4Color and Shape:Single SolutionMolecular weight:492.52Enalapril Maleate
CAS:<p>Enalapril Maleate (MK-421 Maleate), an ACE inhibitor, is utilized in the treatment of hypertension, chronic heart failure, and diabetic nephropathy.</p>Formula:C20H28N2O5·C4H4O4Purity:99.02% - ≥95%Color and Shape:White To Off-White Crystalline Powder SolidMolecular weight:492.52(S,S,S)-Enalapril Maleate
CAS:Formula:C20H28N2O5·C4H4O4Color and Shape:White To Off-WhiteMolecular weight:492.52(S,S,S)-Enalapril maleate - Bio-X ™
CAS:<p>Enalapril is a long-acting angiotensin-converting enzyme inhibitor. It is used to treat hypertension and congestive heart failure, as well as chronic cough due to postnasal drip or bronchitis. Enalapril is an active inhibitor of the synthesis of angiotensin II and other vasoconstrictor substances that are involved in the regulation of blood pressure. It binds reversibly to the active site on angiotensin-converting enzyme (ACE) and blocks its activity by forming strong hydrogen bonds with residues on ACE, thereby preventing it from converting angiotensin I into angiotensin II. This leads to a significant reduction in blood pressure.</p>Formula:C24H32N2O9Purity:Min. 95%Color and Shape:PowderMolecular weight:492.52 g/mol
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