CAS 768-94-5

Amantadine

Description:

Amantadine is an antiviral and antiparkinsonian medication with the chemical formula C10H17N and a CAS number of 768-94-5. It is classified as a tricyclic amine and is known for its ability to inhibit the replication of certain viruses, particularly influenza A, by interfering with the viral M2 protein. In addition to its antiviral properties, amantadine is utilized in the treatment of Parkinson's disease and drug-induced extrapyramidal symptoms due to its dopaminergic effects. The substance is typically administered orally and is well-absorbed in the gastrointestinal tract. Amantadine exhibits a relatively low solubility in water but is soluble in organic solvents. Its mechanism of action involves increasing dopamine release and blocking the reuptake of dopamine, which contributes to its therapeutic effects in Parkinson's disease. Common side effects may include insomnia, dizziness, and gastrointestinal disturbances. Due to its unique properties, amantadine has been a subject of research for various neurological conditions and viral infections.

Formula: C₁₀H₁₇N

InChI: InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2

InChI key: InChIKey=DKNWSYNQZKUICI-UHFFFAOYSA-N

SMILES: NC12CC3CC(C1)CC(C2)C3

Synonyms:

• (Adamantan-1-yl)amine
• 1-Adamantamine
• 1-Adamantanamine
• 1-Adamantylamine
• 1-Amantadine
• 1-Aminoadamantane
• Adamantamine
• Adamantan-1-Amine
• Adamantanamine
• Adamantylamine
• Amantadin
• Amantadina
• Nsc 341865
• Symadine
• Symmetrel
• Tricyclo[3.3.1.1(3,7)]decane-1-amine
• Tricyclo[3.3.1.13,7]decan-1-amine
• Tricyclo[3.3.1.13,7]decane-1-amine
• Tricyclo[3.3.1.1^3,7]decan-1-amine
• Tricyclo[3.3.1.1^3,7]decane-1-amine

1-Adamantanamine (purified by sublimation)

CAS: 768-94-5

Formula: C₁₀H₁₇N

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 151.25

Ref: 3B-A3234

1-Adamantanamine, 98%

CAS: 768-94-5

1-Adamantanamine acts as a catalyst in enantioselective strecker reaction of phosphinoyl imines. It is also useful for making adamantane derivatives, i.e. amantadine hydrochloride. It is used in the pharmaceutical industry as antiviral and an antiparkinsonian drug. This Thermo Scientific Chemicals

Formula: C₁₀H₁₇N

Purity: 98%

Color and Shape: White, Crystals or powder or crystalline powder.

Molecular weight: 151.25

Ref: 02-H30076

1-Aminoadamantane

CAS: 768-94-5

1-Aminoadamantane

Formula: C₁₀H₁₇N

Purity: 95%

Color and Shape: Pale yellow Solid

Molecular weight: 151.24868

Ref: 54-OR14310

Amantadine (1-Adamantanamine)

CAS: 768-94-5

Formula: C₁₀H₁₇N

Color and Shape: White To Off-White Solid

Molecular weight: 151.25

Ref: 4Z-A-613

Amantadine

CAS: 768-94-5

Amantadine

Purity: ≥98%

Molecular weight: 151.25g/mol

Ref: 54-BUP19461

Amantadine

CAS: 768-94-5

Formula: C₁₀H₁₇N

Purity: (GC) ≥ 97.0%

Color and Shape: White to almost white powder or crystals

Molecular weight: 151.25

Ref: 7W-GP0461

1-Aminoadamantane

CAS: 768-94-5

1-Aminoadamantane

Formula: C₁₀H₁₇N

Purity: 98%

Color and Shape: Pale yellow Solid

Molecular weight: 151.24868

Ref: 54-BIA4304

1-Aminoadamantane-d15

CAS: 33830-10-3, 768-94-5

Purity: 99 atom % D

Molecular weight: 166.35

Ref: 3U-D7965

Tricyclo[3.3.1.13,7]decan-1-amine

CAS: 768-94-5

Formula: C₁₀H₁₇N

Purity: 95%

Color and Shape: Solid

Molecular weight: 151.2487

Ref: IN-DA00587E

Amantadine

Controlled Product

CAS: 768-94-5

Applications Amantadine is useful in biology studies. Particularly it has been used for solid-state NMR and membrane protein studies.
References Shigeta, A., et al.: New Developments in NMR, 20, 457 (2019)

Formula: C₁₀H₁₇N

Color and Shape: Neat

Molecular weight: 151.25

Ref: TR-A576008

Amantadine

CAS: 768-94-5

Amantadine (1-Aminoadamantane), an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release and blocks dopamine reuptake.

Formula: C₁₀H₁₇N

Purity: 99.73% - 99.94%

Color and Shape: Solid

Molecular weight: 151.2487

Ref: TM-T7060

Amantadine

CAS: 768-94-5

Adamantan-1-amine

Formula: C₁₀H₁₇N

Purity: 97%

Molecular weight: 151.25

Ref: IN-DG0305

Amantadine

CAS: 768-94-5

Adamantan-1-amine

Formula: C₁₀H₁₇N

Purity: 99%

Molecular weight: 151.25

Ref: IN-DG02535713

Amantadine

Controlled Product

CAS: 768-94-5

NMDA receptor antagonist; anti-viral; anti-Parkinsonian

Formula: C₁₀H₁₇N

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 151.25 g/mol

Ref: 3D-FA07678

1-Adamatanamine in Methanol

CAS: 768-94-5

Methanol

Formula: C₁₀H₁₇N

Color and Shape: Solid

Molecular weight: 151.25

Ref: BE-BePure-20140XM-100

Amantadine

CAS: 768-94-5

Formula: C₁₀H₁₇N

Color and Shape: Solid

Molecular weight: 151.25

Ref: BE-RMCA149003

1-Adamatanamine in Methanol

CAS: 768-94-5

Methanol

Formula: C₁₀H₁₇N

Color and Shape: Solid

Molecular weight: 151.25

Ref: BE-BePure-20140YM-1000

1-Adamatanamine

CAS: 768-94-5

Formula: C₁₀H₁₇N

Color and Shape: Solid

Molecular weight: 151.25

Ref: BE-BePure-20140

Adamantan-1-amine

CAS: 768-94-5

Formula: C₁₀H₁₇N

Purity: 98.00%

Color and Shape: Solid

Molecular weight: 151.253

Ref: 10-F209082

1-Adamantanamine

CAS: 768-94-5

Formula: C₁₀H₁₇N

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 151.25

Ref: 3B-A2318