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CAS 768-94-5

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Amantadine

Description:
Amantadine is an antiviral and antiparkinsonian medication with the chemical formula C10H17N and a CAS number of 768-94-5. It is classified as a tricyclic amine and is known for its ability to inhibit the replication of certain viruses, particularly influenza A, by interfering with the viral M2 protein. In addition to its antiviral properties, amantadine is utilized in the treatment of Parkinson's disease and drug-induced extrapyramidal symptoms due to its dopaminergic effects. The substance is typically administered orally and is well-absorbed in the gastrointestinal tract. Amantadine exhibits a relatively low solubility in water but is soluble in organic solvents. Its mechanism of action involves increasing dopamine release and blocking the reuptake of dopamine, which contributes to its therapeutic effects in Parkinson's disease. Common side effects may include insomnia, dizziness, and gastrointestinal disturbances. Due to its unique properties, amantadine has been a subject of research for various neurological conditions and viral infections.
Formula:C10H17N
InChI:InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
InChI key:InChIKey=DKNWSYNQZKUICI-UHFFFAOYSA-N
SMILES:NC12CC3CC(C1)CC(C2)C3
Synonyms:
  • (Adamantan-1-yl)amine
  • 1-Adamantamine
  • 1-Adamantanamine
  • 1-Adamantylamine
  • 1-Amantadine
  • 1-Aminoadamantane
  • Adamantamine
  • Adamantan-1-Amine
  • Adamantanamine
  • Adamantylamine
  • See more synonyms
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