CAS 80-08-0: Dapsone

Description: Dapsone, with the CAS number 80-08-0, is an aromatic sulfonamide antibiotic primarily used in the treatment of leprosy and certain types of dermatitis, such as dermatitis herpetiformis. It is a white to off-white crystalline powder that is slightly soluble in water and more soluble in organic solvents like ethanol and acetone. Dapsone functions by inhibiting bacterial folate synthesis, thereby exerting its antimicrobial effects. Its chemical formula is C12H12N2O2S, and it has a molecular weight of approximately 240.3 g/mol. Dapsone is known for its anti-inflammatory properties, making it effective in treating autoimmune skin conditions. While generally well-tolerated, it can cause side effects such as hemolytic anemia, especially in individuals with glucose-6-phosphate dehydrogenase deficiency. Monitoring of blood parameters is recommended during treatment. Dapsone is often used in combination with other medications to enhance therapeutic efficacy and reduce the risk of resistance.

Formula: C₁₂H₁₂N₂O₂S

InChI: InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2

InChI key: InChIKey=MQJKPEGWNLWLTK-UHFFFAOYSA-N

SMILES: O=S(=O)(C1=CC=C(N)C=C1)C2=CC=C(N)C=C2

Synonyms:

• 1,1'-Sulfonylbis[4-aminobenzene]
• 1358F
• 4,4'-Dapsone
• 4,4'-Dds
• 4,4'-Diamino Diphenyl Sulfone
• 4,4'-Diamino Diphenyl Sulphone
• 4,4'-Diaminodiphenylsulfon
• 4,4'-Diaminodiphenylsulfone
• 4,4'-Sulfonylbisaniline
• 4,4'-Sulfonylbisbenzamine
• 4,4'-Sulfonyldiphenylamine
• 4,4-Diaminodiphenyl sulfone
• 4,4-Diaminodiphenyl sulphone
• 4,4-Sulfonyldianiline
• 4,4-Sulphonyldianiline
• 4,4′-Diaminobiphenyl sulfone
• 4,4′-Sulfonylbis[benzenamine]
• 4-((4-Aminophenyl)Sulfonyl)Phenylamine
• 4-(4-Aminophenyl)sulfonylaniline
• 4-(4-Aminophenylsulfonyl)benzenamine
• 4-Aminophenyl sulphone
• 44Dds
• Aczone
• Aniline, 4,4'-sulfonyldi-
• Aradur 9664-1
• Aradur 9664-1NL
• Aradur 976
• Aradur 976-1
• Aradur 9761-1
• Araldite HT 976
• Atrisone
• Avlosulfon
• Avlosulfone
• Avlosulphone
• Benzenamine, 4,4'-sulfonylbis-
• Bis(4-aminophenyl) sulfone
• Bis(P-Aminophenyl)Sulfone
• Croysulfone
• Croysulphone
• D 0089
• DDS
• DDS (pharmaceutical)
• DSS
• Dadfs
• Dadps
• Dapson
• Dapsone
• Di(4-Aminophenyl) Sulphone
• Di(4-aminophenyl)sulfone
• Di(p-aminophenyl) sulfone
• Diaminodiphenylsulfone
• Diaphenylsulfon
• Diaphenylsulfone
• Diphenasone
• Diphenyl Sulfone, 4,4'-Diamino-
• Diphone
• Disulone
• Dumitone
• Eporal
• F 1358
• Hardener HT 976
• Hb-Mc-Ge 40
• Hb-Mc-Ge 45
• Hew 62
• Ht 9664
• Ht 976
• Ht 976-1
• Hy 976
• Lapox K 10
• Metabolite C
• Novophone
• Nsc 6091
• P,P'-Sulfonyldianiline
• P-Aminophenyl Sulfone
• Seikacure S
• Servidapson
• Sulfona
• Sulfona-Mae
• Sulphadione
• Sumicure S
• Timtec-Bb Sbb003168
• Udolac
• p,p'-Diaminodiphenyl sulfone

Bis(4-aminophenyl) Sulfone

CAS: 80-08-0

• Formula: C₁₂H₁₂N₂O₂S
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 248.30

4,4'-Diaminodiphenyl sulfone, 98%

CAS: 80-08-0

It is active against a wide range of bacteria, but is mainly employed for its …

• Formula: C₁₂H₁₂N₂O₂S
• Purity: 98%
• Color and Shape: White to pale cream, Powder
• Molecular weight: 248.30

Dapsone RS

CAS: 80-08-0

• Formula: C₁₂H₁₂N₂O₂S
• Color and Shape: Powder
• Molecular weight: 248.3009

Dapsone CRS

CAS: 80-08-0

• Formula: C₁₂H₁₂N₂O₂S
• Color and Shape: Powder
• Molecular weight: 248.3009

Dapsone

CAS: 80-08-0

• Formula: C₁₂H₁₂N₂O₂S
• Purity: 100.0%
• Color and Shape: White
• Molecular weight: 248.06195

Dapsone

CAS: 80-08-0

Other aromatic organo-sulfur compounds (excluding pesticides)

• Formula: C₁₂H₁₂N₂O₂S
• Color and Shape: White Off-White Light Yellow Crystalline Powder
• Molecular weight: 248.06195

4,4'-Sulfonyldianiline

CAS: 80-08-0

• Formula: C₁₂H₁₂N₂O₂S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 248.30088

Dapsone

CAS: 80-08-0

Dapsone (Sulphadione) has activity against a wide range of bacteria but mainly employed for its …

• Formula: C₁₂H₁₂N₂O₂S
• Purity: 99.84%
• Color and Shape: White To Creamy Solid Crystalline
• Molecular weight: 248.3

Bis(4-aminophenyl) Sulfone

CAS: 80-08-0

• Formula: C₁₂H₁₂N₂O₂S
• Purity: 97%
• Color and Shape: off-white solid
• Molecular weight: 248.30g/mol

Dapsone

CAS: 80-08-0

• Formula: C₁₂H₁₂N₂O₂S
• Purity: (Titration) 98.0 - 102.0 %
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 248.30

Dapsone

CAS: 80-08-0

• Formula: C₁₂H₁₂N₂O₂S
• Molecular weight: 248.30

Dapsone

CAS: 80-08-0

• Purity: 99%
• Molecular weight: 248.3g/mol

Dapson 100 µg/mL in Methanol

CAS: 80-08-0

• Formula: C₁₂H₁₂N₂O₂S
• Color and Shape: Single Solution
• Molecular weight: 248.30

Smart Solutions™ v59 PharmaVetResiMix Kit 1

CAS: 100-90-3 113507-06-5 115550-35-1 117704-25-3 119478-55-6 122-11-2 1220-83-3 123997-26-2 127-71-9 127-79-7 144-82-1 144-83-2 14698-29-4 148-79-8 149676-40-4 155569-91-8 19562-30-2 20559-55-1 2447-57-6 28657-80-9 31430-15-6 31431-39-7 389-08-2 42835-25-6 43210-67-9 515-64-0 51940-44-4 53716-50-0 54029-12-8 54965-21-8 57-67-0 57-68-1 58306-30-2 59-40-5 63-74-1 651-06-9 68-35-9 68786-66-3 70288-86-7 70458-96-7 71751-41-2 72-14-0 723-46-6 729-99-7 74011-58-8 75184-71-3 79660-72-3 80-08-080-32-0 80-35-3 80983-34-2 82419-36-1 85721-33-1 88254-99-3 91296-86-5 91296-87-6 93106-60-6 948-71-0 98079-52-8

• Color and Shape: Mixture

Dapsone

CAS: 80-08-0

• Formula: C₁₂H₁₂N₂O₂S
• Color and Shape: Neat
• Molecular weight: 248.30

Dapson

CAS: 80-08-0

• Formula: C₁₂H₁₂N₂O₂S
• Color and Shape: Neat
• Molecular weight: 248.30

4-Aminophenyl sulfone, 97%

CAS: 80-08-0

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₂H₁₂N₂O₂S
• Purity: 97%
• Color and Shape: Crystalline powder, White to beige
• Molecular weight: 248.30

PharmaVetResiMix 4 Sulfonamides-v21 10 µg/mL in Methanol

CAS: 100-90-3 122-11-2 1220-83-3 127-71-9 127-79-7 144-82-1 144-83-2 2447-57-6 515-64-0 57-67-0 57-68-1 59-40-5 63-74-1 651-06-9 68-35-9 72-14-0 723-46-6 729-99-7 80-08-080-32-0 80-35-3

• Color and Shape: Mixture

4-[(4-aminobenzene)sulfonyl]aniline

CAS: 80-08-0

• Purity: 97.0%
• Color and Shape: Solid
• Molecular weight: 248.3000030517578

Dapsone

CAS: 80-08-0

Applications An antibacterial used in the treatment of dermatitis herpetiformis. References Francis, J., et al.: …

• Formula: C₁₂H₁₂N₂O₂S
• Color and Shape: White
• Molecular weight: 248.30