CAS 82640-04-8
:Raloxifene hydrochloride
Description:
Raloxifene hydrochloride is a selective estrogen receptor modulator (SERM) primarily used in the treatment and prevention of osteoporosis in postmenopausal women. It exhibits estrogenic activity on bone tissue, helping to maintain bone density, while acting as an antagonist in breast and uterine tissues, thus reducing the risk of estrogen-related cancers. The compound is characterized by its ability to bind to estrogen receptors, influencing gene expression and cellular activity. Raloxifene hydrochloride is typically administered orally and is known for its favorable pharmacokinetic profile, including good absorption and a relatively long half-life. Common side effects may include hot flashes, leg cramps, and an increased risk of thromboembolic events. The substance is also investigated for its potential cardiovascular benefits and its role in reducing the risk of invasive breast cancer. As with any medication, it is essential to consider contraindications and interactions with other drugs when prescribing or using Raloxifene hydrochloride.
Formula:C28H27NO4S·ClH
InChI:InChI=1S/C28H27NO4S.ClH/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29;/h4-13,18,30-31H,1-3,14-17H2;1H
InChI key:InChIKey=BKXVVCILCIUCLG-UHFFFAOYSA-N
SMILES:C(=O)(C1=C(SC=2C1=CC=C(O)C2)C3=CC=C(O)C=C3)C4=CC=C(OCCN5CCCCC5)C=C4.Cl
Synonyms:- 2-(4-Hydroxyphenyl)-3-[4-[2-(piperidin-1-yl)ethoxy]benzoyl]-1-benzothiophen-6-ol hydrochloride
- 6-Hydroxy-2-(p-hydroxyphenyl)benzo(b)thien-3-yl-p-(2-piperidinoethoxy)phenyl ketone, hydrochloride
- Bonebay
- Bontact
- Evista
- Fiona
- Keoxifene hydrochloride
- Ly 156758
- Methanone, (6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)-, hydrochloride
- Methanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-, hydrochloride (1:1)
- Optruma
- Ralista
- Ralofen
- Raloxifene HCl
- Raloxifene hydrochloride [USAN]
- Reloxafine
- Unii-4F86W47Br6
- [6-Hydroxy-2-(4-Hydroxyphenyl)-1-Benzothiophen-3-Yl]{4-[2-(Piperidin-1-Yl)Ethoxy]Phenyl}Methanone Hydrochloride (1:1)
- [6-Hydroxy-2-(4-Hydroxyphenyl)-2,3-Dihydro-1-Benzothiophen-3-Yl][4-(2-Piperidin-1-Ylethoxy)Phenyl]Methanone
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Found 15 products.
Raloxifene Hydrochloride
CAS:Formula:C28H27NO4S·HClPurity:>98.0%(T)(HPLC)Color and Shape:Light yellow to Yellow to Green powder to crystalMolecular weight:510.05RALOXIFENE FOR PEAK IDENTIFICATION CRS
CAS:<p>RALOXIFENE FOR PEAK IDENTIFICATION CRS</p>Formula:C28H28ClNO4SMolecular weight:510.0442RALOXIFENE HYDROCHLORIDE CRS
CAS:<p>RALOXIFENE HYDROCHLORIDE CRS</p>Formula:C28H28ClNO4SColor and Shape:AddedMolecular weight:510.0442Raloxifene Hydrochloride
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C28H27NO4S·HClColor and Shape:Off-White Light Yellow Yellow Green PowderMolecular weight:473.16608Raloxifene hydrochloride
CAS:<p>Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.</p>Formula:C28H28ClNO4SPurity:98% - 99.97%Color and Shape:Light Yellow SolidMolecular weight:510.044Methanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-,hydrochloride (1:1)
CAS:Formula:C28H28ClNO4SPurity:98%Color and Shape:SolidMolecular weight:510.0442Raloxifene hydrochloride
CAS:Formula:C28H27NO4S·HClPurity:≥ 99.0%Color and Shape:Light yellow crystalline powderMolecular weight:510.04Raloxifene Hydrochloride
CAS:Controlled ProductFormula:C28H27NO4S·ClHColor and Shape:NeatMolecular weight:510.04Raloxifene Hydrochloride
CAS:Controlled Product<p>Applications A nonsteroidal, selective estrogen receptor modulator (SERM). Antiosteoporotic.Insoluble in water.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jone, C.D., et al.: J. Med. Chem., 27, 1057 (1984), Buelke-Sam, J., et al.: Reprod. Toxicol., 12, 217 (1998),<br></p>Formula:C28H27NO4S·ClHColor and Shape:Light Yellow SolidMolecular weight:510.04Raloxifene HCl - Bio-X ™
CAS:Controlled Product<p>Raloxifene is an estrogen receptor modulator that is used in the prevention and treatment of osteoporosis and breast cancer in postmenopausal women. This drug acts as an estrogen agonist and antagonist. Also, Raloxifene has antiproliferative effects.</p>Formula:C28H27NO4S•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:510.04 g/molRaloxifene hydrochloride
CAS:Controlled Product<p>Estrogen receptor modulator</p>Formula:C28H28ClNO4SPurity:Min. 95%Color and Shape:Off-White PowderMolecular weight:510.04 g/molRaloxifene-d10 Hydrochloride
CAS:Controlled Product<p>Applications Raloxifene-d10 Hydrochloride, is the labeled analogue of Raloxifene (R100000), a nonsteroidal, selective estrogen receptor modulator (SERM). Antiosteoporotic.<br>References Jone, C.D., et al.: J. Med. Chem., 27, 1057 (1984), Buelke-Sam, J., et al.: Reprod. Toxicol., 12, 217 (1998),<br></p>Formula:C28H18D10ClNO4SColor and Shape:NeatMolecular weight:520.11
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