![2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorop…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F375406-2-pyridinecarboxamide-4-4-4-chloro-3-trifluoromethyl-phenyl-amino-carbonyl-amino-3-fluorophenoxy-1-oxide.webp&w=3840&q=75)
CAS 835621-12-0
:2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-, 1-oxide
Description:
2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-, 1-oxide, identified by CAS number 835621-12-0, is a synthetic organic compound characterized by its complex molecular structure, which includes a pyridine ring, multiple aromatic systems, and various functional groups such as amides and halogens. This compound typically exhibits properties associated with its heterocyclic and aromatic nature, including potential solubility in polar solvents and moderate stability under standard conditions. The presence of chlorine and trifluoromethyl groups suggests that it may possess unique electronic properties, potentially influencing its reactivity and biological activity. Additionally, the compound's structure indicates that it may be of interest in pharmaceutical research, particularly in the development of targeted therapies or as a biochemical probe. Its specific interactions, such as binding affinity to biological targets, would require empirical investigation to fully understand its potential applications and safety profile.
Formula:C20H13ClF4N4O4
InChI:InChI=1S/C20H13ClF4N4O4/c21-14-3-1-10(7-13(14)20(23,24)25)27-19(31)28-16-4-2-11(8-15(16)22)33-12-5-6-29(32)17(9-12)18(26)30/h1-9H,(H2,26,30)(H2,27,28,31)
InChI key:InChIKey=JPEWXTSDCNCZOD-UHFFFAOYSA-N
SMILES:O(C=1C=C(C(N)=O)N(=O)=CC1)C2=CC(F)=C(NC(NC3=CC(C(F)(F)F)=C(Cl)C=C3)=O)C=C2
Synonyms:- 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-, 1-oxide
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Found 10 products.
N-Desmethyl Regorafenib N-Oxide (M5 Metabolite)
CAS:Formula:C20H13ClF4N4O4Color and Shape:White To Off-White SolidMolecular weight:484.80N-Desmethyl Regorafenib-d3 N-Oxide
CAS:Formula:C20H10D3ClF4N4O4Color and Shape:Yellow SolidMolecular weight:487.812-Carbamoyl-4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)pyridine 1-oxide
CAS:<p>2-Carbamoyl-4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)pyridine 1-oxide</p>Purity:97%Molecular weight:484.79g/molN-Desmethyl Regorafenib (Pyridine)-N-oxide-d3
CAS:Controlled Product<p>Applications N-Desmethyl Regorafenib (Pyridine)-N-oxide-d3 is the isotope labelled analog of N-Desmethyl Regorafenib (Pyridine)-N-oxide (D293280); a synthetic metabolite of Regorafenib (R143000) used for treatment and prevention of cancer.<br>References Wilhelm, S.: PCT Int. Appl. WO 2011130728 A1 20111020. Oct 20, 2011<br></p>Formula:C20D3H10ClF4N4O4Color and Shape:NeatMolecular weight:487.807N-Desmethyl Regorafenib (Pyridine)-N-oxide
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications N-Desmethyl Regorafenib (Pyridine)-N-oxide is a synthetic metabolite of Regorafenib (R143000) and is used for treatment and prevention of cancer.<br>References Wilhelm, S.: PCT Int. Appl. WO 2011130728 A1 20111020. Oct 20, 2011<br></p>Formula:C20H13ClF4N4O4Color and Shape:NeatMolecular weight:484.79Regorafenib metabolite M5
CAS:<p>Regorafenib metabolite M5 is a drug product that is custom synthesized by our company and has high purity. It can be used in metabolism studies, drug development, and pharmacopoeia due to its natural origin. It is also a synthetic compound that can be used as an impurity standard or research and development standard in HPLC.</p>Formula:C20H13ClF4N4O4Purity:Min. 95%Molecular weight:484.79 g/molN-desmethyl Regorafenib N-oxide
CAS:<p>N-Desmethyl Regorafenib N-oxide, an active metabolite of the multi-kinase inhibitor regorafenib, originates through the action of the cytochrome P450 (CYP) isoform CYP3A4. This compound demonstrates efficacy in vitro by inhibiting key enzymes such as VEGFR2, Tie2, c-Kit, and B-RAF, and it exhibits tumor growth inhibition in HT-29 and MDA-MB-231 mouse xenograft models at a dosage of 1 mg/kg.</p>Formula:C20H13ClF4N4O4Color and Shape:SolidMolecular weight:484.79
