CAS 846-49-1

2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-

Description:

The chemical substance known as 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy- (CAS number 846-49-1) is a member of the benzodiazepine family, which is characterized by a fused benzene and diazepine ring structure. This compound typically exhibits psychoactive properties, often functioning as a central nervous system depressant. Its structure includes a chloro substituent at the 7-position and a 2-chlorophenyl group at the 5-position, which can influence its pharmacological activity and potency. The presence of a hydroxy group at the 3-position contributes to its chemical reactivity and potential interactions with biological targets. Benzodiazepines are commonly used for their anxiolytic, sedative, and muscle relaxant effects, although they may also pose risks of dependence and withdrawal. The specific characteristics, such as solubility, melting point, and stability, can vary based on the compound's formulation and purity. As with all chemical substances, proper handling and safety precautions are essential due to potential toxicity and regulatory considerations.

Formula:C₁₅H₁₀Cl₂N₂O₂

InChI:InChI=1/C15H10Cl2N2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20)

InChI key:InChIKey=DIWRORZWFLOCLC-UHFFFAOYSA-N

SMILES:ClC1=C(C=2C=3C(NC(=O)C(O)N2)=CC=C(Cl)C3)C=CC=C1

Synonyms:

(.+-.)-Lorazepam
(RS)-Lorazepam
2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-
7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1H-1,4-benzodiazepin-2(3H)-one
7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
Almazine
Anxiedin
Anxira
Anzepam
Aplacasse
Aplacassee
Apo-Lorazepam
Aripax
Ativan
Azurogen
Bonatranquan
Bonton
Control
Delormetazepam
Demethyllormetazepam
Duralozam
Efasedan
Emotival
Equitam
Kalmalin
Larpose
Laubeel
Lopam
Lorabenz
Loram
Lorans
Lorapam
Lorat
Lorax
Lorazem
Lorazene
Lorazep
Lorazin
Lorazon
Lorenin
Loridem
Lorivan
Lorsedal
Lorsilan
Lorzem
Lozepam
Merlit
NIC
Nervistop L
Norlormetazepam
Novhepar
Novo-lorazem
Nsc 289758
Orfidal
Pro Dorm
Psicopax
Punktyl
Quait
Renaquil
Reposepan
Rocosgen
Securit
Sedatival
Sedazin
Sedizepan
Sidenar
Silence
Sinestron
Somagerol
Stapam
Tavor
Tavor Expidet
Temesta
Titus
Tranqipam
Trapax
Trapex
Upan
Wintin
Wy 4036
Wypax
o-Chlorooxazepam
o-Chloroxazepam
2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-
(+-)-lorazepam--dea schedule iv item
1,4-benzodiazepin-2-one,7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2
AURORA KA-7219
7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one
See more synonyms

Purity (%)

100

Found 15 products.

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Lorazepam
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 846-49-1
Color and Shape:Neat
Ref: 61-FOR0071.00
10mg
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Lorazepam, 1mg/ml in Acetonitrile
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 846-49-1
Color and Shape:Single Solution
Ref: LP-LOR-142-1LA
1ml
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Lorazepam 1.0 mg/ml in Acetonitrile
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 846-49-1
Color and Shape:Single Solution
Ref: 61-AMP0071.00-11
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Lorazepam
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 846-49-1
Color and Shape:Neat
Ref: LP-LOR-142-10
10mg
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50mg
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100mg
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Lorazepam 0.1 mg/ml in Acetonitrile
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 846-49-1
Color and Shape:Single Solution
Ref: 61-AMP0071.00-12
1ml
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Lorazepam
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 846-49-1
Color and Shape:Neat
Ref: 86-MM0071.00
250mg
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Lorazepam
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 846-49-1
Impurity Lorazepam USP Related Compound A
Stability hygroscopic
Applications Lorazepam is an anxiolytic compound that potentiates GABAergic synaptic transmission by binding at the benzodiazepine site on the GABAA receptor.1,2 This product is intended for forensic and research applications. Lorazepam acts as ananticonvulsant. Lorazepam USP Related Compound A.Controlled substance (depressant).
References Rutgers, G., et al.: Anal. Profiles Drug Subs., 9, 397 (1980), Korkmaz, S., et al.: Eur. Neuropsychopharmacol., 8, 175 (1998), D’Onofrio, G., et al.: N. Engl. J. Med., 340, 915 (1999),
Formula:C₁₅H₁₀Cl₂N₂O₂
Color and Shape:Neat
Molecular weight:321.16
Ref: TR-L469850
1g
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5mg
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100mg
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Lorazepam
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 846-49-1
Lorazepam is a benzodiazepine that binds to the benzodiazepine receptor in the central nervous system. This binding induces a variety of effects, including sedation, muscle relaxation, and suppression of anxiety. Lorazepam can be used as an antianxiety agent and as an adjunct to anesthesia. Lorazepam is metabolized by oxidation at the 3-position to produce lorazepam-3-glucuronide (LZG), which is excreted in urine. The major metabolic pathway involves glucuronidation followed by biliary excretion of LZG. Benzalkonium chloride has been used for analytical purposes in chromatographic analysis with minimal toxicity.
Formula:C₁₅H₁₀Cl₂N₂O₂
Purity:Min. 95%
Color and Shape:Slightly Yellow Powder
Molecular weight:321.16 g/mol
Ref: 3D-FL24937
25mg
202.00€
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50mg
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100mg
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250mg
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LORAZEPAM FOR SYSTEM SUITABILITY CRS - * PSY (LORAZEPAM)
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CAS:
- 846-49-1
LORAZEPAM FOR SYSTEM SUITABILITY CRS - * PSY (LORAZEPAM)
Formula:C₁₅H₁₀Cl₂N₂O₂
Molecular weight:321.1581
Ref: 41-Y0000576
0.8mg
132.00€
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LORAZEPAM CRS - * PSY
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CAS:
- 846-49-1
LORAZEPAM CRS - * PSY
Formula:C₁₅H₁₀Cl₂N₂O₂
Color and Shape:Crystalline Powder. White. Powder.
Molecular weight:321.1581
Ref: 41-L0750500
15mg
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Lorazepam
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CAS:
- 846-49-1
Lorazepam
Formula:C₁₅H₁₀Cl₂N₂O₂
Purity:99.7%
Color and Shape:White Crystalline
Molecular weight:320.01193
Ref: 47-434
100mg
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Lorazepam (100 μg/mL in Acetonitrile)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 846-49-1
Formula:C₁₅H₁₀Cl₂N₂O₂
Color and Shape:Single Solution
Molecular weight:321.16
Ref: TR-KIT0880
10x1ml
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Lorazepam (1.0 mg/mL in Acetonitrile)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 846-49-1
Formula:C₁₅H₁₀Cl₂N₂O₂
Color and Shape:Single Solution
Molecular weight:321.16
Ref: TR-KIT0625
10x1ml
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Lorazepam CIV
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 846-49-1
Alprazolam(inn), camazepam (inn), chlordiazepoxide (inn), clonazepam (inn), clorazepate & other heterocyclic compounds with nitro atom(s) only
Formula:C₁₅H₁₀Cl₂N₂O₂
Color and Shape:White Off-White Crystalline Powder
Molecular weight:320.01193
Ref: 45-1370305
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N-Nitroso Lorazepam
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 846-49-1
Applications N-Nitroso Lorazepam is an impurity of Lorazepam (L469850), which is an anxiolytic compound that potentiates GABAergic synaptic transmission by binding at the benzodiazepine site on the GABAA receptor.1,2 This product is intended for forensic and research applications. Lorazepam acts as ananticonvulsant.
References Rutgers, G., et al.: Anal. Profiles Drug Subs., 9, 397 (1980), Korkmaz, S., et al.: Eur. Neuropsychopharmacol., 8, 175 (1998), D’Onofrio, G., et al.: N. Engl. J. Med., 340, 915 (1999),
Formula:C₁₅H₉Cl₂N₃O₃
Color and Shape:Neat
Molecular weight:350.16
Ref: TR-N469850
100mg
Discontinued
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250mg
Discontinued
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Discontinued product