CAS: 848942-61-0 - 2-[4-({4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl}oxy)-1-piperidinyl]-N-methylacetamide

Formula: C₂₃H₂₅ClFN₅O₃

InChI: InChI=1S/C23H25ClFN5O3/c1-26-21(31)12-30-8-6-14(7-9-30)33-20-10-15-18(11-19(20)32-2)27-13-28-23(15)29-17-5-3-4-16(24)22(17)25/h3-5,10-11,13-14H,6-9,12H2,1-2H3,(H,26,31)(H,27,28,29)

InChI key: InChIKey=DFJSJLGUIXFDJP-UHFFFAOYSA-N

SMILES: O=C(NC)CN1CCC(OC2=CC=3C(=NC=NC3NC=4C=CC=C(Cl)C4F)C=C2OC)CC1

Synonyms:

• 1-Piperidineacetamide, 4-[[4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-N-methyl-
• 2-[4-[4-(3-Chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypiperidin-1-yl]-N-methylacetamide
• 4-(3-Chloro-2-fluoroanilino)-7-methoxy-6-[[1-(N-methylcarbamoylmethyl)piperidin-4-yl]oxy]quinazoline
• 4-[[4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-N-methyl-1-piperidineacetamide
• Azd-8931
• Azd8931
• Sapatinib
• Sapitinib

AZD8931

CAS: 848942-61-0

• Formula: C₂₃H₂₅ClFN₅O₃
• Purity: ≥98%
• Color and Shape: Solid
• Molecular weight: 473.9277

Sapitinib

CAS: 848942-61-0

Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 …

• Formula: C₂₃H₂₅ClFN₅O₃
• Purity: 99.83%
• Color and Shape: Solid
• Molecular weight: 473.93

Sapatinib

CAS: 848942-61-0

• Formula: C₂₃H₂₅ClFN₅O₃
• Color and Shape: Neat
• Molecular weight: 473.928

2-(4-(4-(3-chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)piperidin-1-yl)-N-methylacetamidef

CAS: 848942-61-0

2-(4-(4-(3-Chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)piperidin-1-yl)-N-methylacetamide (F) is a reactive compound that has been shown to have anticancer activity. It …

• Purity: Min. 95%