CAS: 849217-68-1 - 1,1-Cyclopropanedicarboxamide,N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-

Formula: C₂₈H₂₄FN₃O₅

InChI: InChI=1S/C28H24FN3O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34)

InChI key: InChIKey=ONIQOQHATWINJY-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=C(F)C=C1)C2(C(=O)NC3=CC=C(OC=4C=CN=C5C=C(OC)C(OC)=CC54)C=C3)CC2

Synonyms:

• 1-N-[4-(6,7-Dimethoxyquinolin-4-yl)oxyphenyl]-1-N′-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
• Bms-907351
• Cabometyx
• Cabozantinib
• N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
• N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
• Xl 184
• Xl184

Cabozantinib

CAS: 849217-68-1

• Formula: C₂₈H₂₄FN₃O₅
• Color and Shape: White To Off-White Solid
• Molecular weight: 501.51

Cabozantinib

CAS: 849217-68-1

Cabozantinib

CAS: 849217-68-1

Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, …

• Formula: C₂₈H₂₄FN₃O₅
• Purity: 99.59% - 99.88%
• Color and Shape: Solid
• Molecular weight: 501.51

XL184

CAS: 849217-68-1

• Formula: C₂₈H₂₄FN₃O₅
• Color and Shape: White To Off-White
• Molecular weight: 501.51

XL184

CAS: 849217-68-1

Pan-tyrosine kinase inhibitor (VEGFR2, c-MET, RET, KIT); anti-neoplastic

• Formula: C₂₈H₂₄FN₃O₅
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 501.51 g/mol