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CAS 86393-32-0

:

Ciprofloxacin hydrochloride monohydrate

Description:
Ciprofloxacin hydrochloride monohydrate is a synthetic antibiotic belonging to the fluoroquinolone class, primarily used to treat bacterial infections. It is characterized by its broad-spectrum activity against both Gram-positive and Gram-negative bacteria, making it effective for various infections, including urinary tract infections and respiratory tract infections. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in oral and intravenous forms. Its chemical structure includes a bicyclic core with a fluorine atom, which enhances its antibacterial potency. The monohydrate form indicates the presence of one molecule of water associated with each molecule of ciprofloxacin hydrochloride, influencing its stability and solubility. The compound's mechanism of action involves the inhibition of bacterial DNA gyrase and topoisomerase IV, crucial enzymes for bacterial DNA replication and repair. Ciprofloxacin hydrochloride monohydrate is generally well-tolerated, but it may have side effects, including gastrointestinal disturbances and potential effects on tendons. Proper dosage and adherence to guidelines are essential to minimize resistance development.
Formula:C17H18FN3O3·ClH·H2O
InChI:InChI=1S/C17H18FN3O3.ClH.H2O/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;;/h7-10,19H,1-6H2,(H,23,24);1H;1H2
InChI key:InChIKey=ARPUHYJMCVWYCZ-UHFFFAOYSA-N
SMILES:O=C1C=2C(N(C=C1C(O)=O)C3CC3)=CC(=C(F)C2)N4CCNCC4.Cl.O
Synonyms:
  • 1-Cyclopropyl-6-Fluoro-4-Oxo-7-(Piperazin-1-Yl)-1,4-Dihydroquinoline-3-Carboxylic Acid Hydrochloride Hydrate
  • 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride monohydrate
  • 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid, monohydrochloride, monohydrate
  • 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride, hydrate (1:1:1)
  • 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, monohydrochloride, monohydrate
  • Ciprofloxacin Monohydrochloridecas monohydrate
  • Ciprofloxacin hcl monohydrate
  • Ciprofloxacin hydrochloride hydrate
  • Ciprofloxacin hydrochloride monohydrate
  • Ciprofloxacine Hcl Monohydrate Ep6
  • Ciprofloxacin Monohydrochioride
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