![N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F48310-n-4-cyano-3-trifluoromethyl-phenyl-2-methyl-2-oxiranecarboxamide.webp&w=3840&q=75)
CAS 90357-51-0
:N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide
Description:
N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide, with the CAS number 90357-51-0, is a chemical compound characterized by its unique structure, which includes an epoxide functional group (oxirane) and a cyano group attached to a phenyl ring. The presence of a trifluoromethyl group enhances its chemical stability and lipophilicity, making it potentially useful in various applications, including pharmaceuticals and agrochemicals. The compound's epoxide functionality suggests it may participate in ring-opening reactions, which can lead to the formation of diverse derivatives. Additionally, the cyano group can contribute to the compound's reactivity and polarity, influencing its solubility and interaction with biological systems. Overall, this compound's distinctive features make it a subject of interest in synthetic chemistry and material science, although specific applications would depend on further research into its properties and behavior in different environments.
Formula:C12H9F3N2O2
InChI:InChI=1S/C12H9F3N2O2/c1-11(6-19-11)10(18)17-8-3-2-7(5-16)9(4-8)12(13,14)15/h2-4H,6H2,1H3,(H,17,18)
InChI key:InChIKey=UQUQTWDUTIAAAY-UHFFFAOYSA-N
SMILES:C(NC1=CC(C(F)(F)F)=C(C#N)C=C1)(=O)C2(C)CO2
Synonyms:- 1,2-Epoxy-2-Methyl-N-[4-Cyano-3-(Trifluoromethyl)]
- 1,2-Epoxy-2-Methyl-N[4-Cyano-3(Trifluoromethyl)-Phenyl]Propanamide
- 2-Methyl-oxirane-2-carboxylic acid (4-cyano-3-trifluoromethylphenyl)-amide
- 2-Methyloxirane-2-carboxylic acid N-(4-cyano-3-trifluoromethylphenyl)amide
- 2-Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-
- 4'-Cyano-3'-trifluoromethyl-2,3-epoxy-2-methylpropioanilide
- Carboxamide
- N-[4-Cyano-3-(Triflouromethyl)Phenyl]-2-Methyl-2-Oxirane Carboxamide
- N-[4-Cyano-3-(Trifluoromethyl)Phenyl]Methacrylamide Epoxide
- N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide
- N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-oxiranecarboxamide
- N-[4-Cyano-3-(trifluoromethyl)phenyl]-methacrylamide exoxide
- N-[4-Cyano-3-Trifluoromethy Phenyl]-2-Oxirane Carboxamide
- N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-oxiranecarboxamide
- N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
- Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-
- Phenyl]-2-methyl-2-oxirane
- See more synonyms
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Found 9 products.
Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-
CAS:Formula:C12H9F3N2O2Purity:98%Color and Shape:SolidMolecular weight:270.2073Bicalutamide Impurity 3 (Bicalutamide Epoxide Impurity)
CAS:Formula:C12H9F3N2O2Color and Shape:White To Off-White SolidMolecular weight:270.21N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide
CAS:N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamidePurity:98%Molecular weight:270.21g/mol1,2-Epoxy-2-methyl-N-[4-cyano-3-(trifluoromethyl)-phenyl]propionamide
CAS:Controlled ProductFormula:C12H9F3N2O2Color and Shape:NeatMolecular weight:270.21N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
CAS:Formula:C12H9F3N2O2Purity:>95.0%(GC)Color and Shape:White to Almost white powder to crystalMolecular weight:270.21N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide
CAS:Controlled ProductImpurity Bicalutamide Oxirane Impurity / Bicalutamide Epoxide Impurity
Applications N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide, is an intermediate in synthesis of more complex pharmaceutical compounds. It is used in the synthesis of potential impurities of Bicalutamide (B382000), which is an oral nonsteroidal, anti-androgen drug used for prostate cancer.
References Nandu Baban, B., et al.: Synthetic Communications, 39, 1516 (2009);Formula:C12H9F3N2O2Color and Shape:NeatMolecular weight:270.21N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide
CAS:Formula:C12H9F3N2O2Purity:98%Color and Shape:SolidMolecular weight:270.211N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
CAS:N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide (NUOX) is a potential anticancer agent that has been shown to have an acidic pKa of 5.8 and to be active against cancer cells in the same way as bicalutamide, which is a known antiandrogen. NUOX has been shown to increase the number of cavities in polybenzimidazole (PBI) films by enhancing the rate of oxidation. NUOX also inhibits the growth of human cancer cells by binding sulfide groups on proteins and DNA, inhibiting cellular respiration. NUOX is not water soluble, so it must be dissolved in solvents such as acetonitrile or chloroform before administration.Formula:C12H9F3N2O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:270.21 g/mol
![Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00IG48.jpg&w=3840&q=75)
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![N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb%2FIC58274.jpg&w=3840&q=75)
