CAS 951-78-0

Deoxyuridine

Description:

Deoxyuridine is a nucleoside that plays a crucial role in the synthesis of DNA. It consists of a deoxyribose sugar molecule linked to a uracil base, which is one of the four nucleobases found in RNA, but in DNA, it is replaced by thymine. The chemical formula of deoxyuridine is C9H11N2O5, and it has a molecular weight of approximately 227.24 g/mol. Deoxyuridine is typically a white to off-white crystalline powder that is soluble in water and exhibits a slightly acidic to neutral pH in solution. It is involved in various biochemical processes, including DNA replication and repair, and serves as a substrate for the enzyme thymidine kinase, which phosphorylates it to form deoxyuridine triphosphate (dUTP). This compound is also of interest in research and therapeutic applications, particularly in the study of nucleic acid metabolism and as a potential antiviral agent. Its CAS number is 951-78-0, which uniquely identifies it in chemical databases.

Formula: C₉H₁₂N₂O₅

InChI: InChI=1S/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m0/s1

InChI key: InChIKey=MXHRCPNRJAMMIM-SHYZEUOFSA-N

SMILES: O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=CC(=O)N1

Synonyms:

• 1-(2-Deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)uracil
• 1-(2-Deoxy-β-D-erythro-pentofuranosyl)uracil
• 1-(2-deoxy-alpha-L-erythro-pentofuranosyl)pyrimidine-2,4(1H,3H)-dione
• 1-(2-deoxy-beta-L-erythro-pentofuranosyl)pyrimidine-2,4(1H,3H)-dione
• 1-(2-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione
• 1-[(3xi)-2-deoxy-beta-D-glycero-pentofuranosyl]pyrimidine-2,4(1H,3H)-dione
• 2'-Desoxiuridina
• 2'-Desoxyuridin
• 2'-Desoxyuridine
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-D-ribofuranosyl)-
• Deoxyribose uracil
• Deoxyuridine
• Nsc 23615
• Uracil deoxyriboside
• Uridine, 2'-deoxy-
• 2-Deoxyuridine

2'-Deoxyuridine

CAS: 951-78-0

Formula: C₉H₁₂N₂O₅

Purity: >99.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 228.20

Ref: 3B-D0060

2'-Deoxyuridine, 98+%

CAS: 951-78-0

2'-Deoxyuridine is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms. Derivatized 2?-Deoxyuridines used as labeling substrates include chloro-2?-deoxyuridine (CldU), bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU). Other useful

Formula: C₉H₁₂N₂O₅

Purity: 98+%

Color and Shape: Crystals or powder or crystalline powder, White to pale cream

Molecular weight: 228.20

Ref: 02-A16026

1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

CAS: 951-78-0

Formula: C₉H₁₂N₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 228.2020

Ref: IN-DA005T5P

2'-Deoxyuridine

CAS: 951-78-0

2'-Deoxyuridine (2-deoxyuridine).

Formula: C₉H₁₂N₂O₅

Purity: 98.51% - 99.88%

Color and Shape: Solid

Molecular weight: 228.2

Ref: TM-T1721

2'-Deoxyuridine

CAS: 951-78-0

2'-Deoxyuridine

Purity: ≥98%

Molecular weight: 228.2g/mol

Ref: 54-BUP15860

2'-Deoxyuridine

CAS: 951-78-0

2'-Deoxyuridine

Formula: C₉H₁₂N₂O₅

Purity: ≥95%

Color and Shape: white crystalline powder

Molecular weight: 228.20g/mol

Ref: 54-OR0326

2'-Deoxyuridine-2-13C;1,3-15N

CAS: 369656-76-8, 951-78-0

Purity: 99 atom % 13C; 99 atom % 15N

Color and Shape: White Solid

Molecular weight: 231.23

Ref: 3U-M5445

2'-Desoxyuridine

CAS: 951-78-0

Formula: C₉H₁₂N₂O₅

Purity: 95%~99%

Molecular weight: 228.204

Ref: BP-BP4234

2''-Deoxyuridine

CAS: 951-78-0

Formula: C₉H₁₂N₂O₅

Purity: ≥ 99.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 228.21

Ref: 7W-GE3235

2'-Deoxyuridine

CAS: 951-78-0

Applications An uridine derivative as therapeutic agent for treating allergy, cancer, infection and autoimmune disease.
References Fu, M., et al.: J. Biol. Chem., 271, 9982 (1996), Thornalley, P., et al.: Biochem. J., et al.: 344, 109 (1999), Munter, T., et al.: Chem. Res. Toxicol., 15, 1549 (2002)

Formula: C₉H₁₂N₂O₅

Color and Shape: Neat

Molecular weight: 228.2

Ref: TR-D288010

1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

CAS: 951-78-0

Formula: C₉H₁₂N₂O₅

Purity: 97%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 228.204

Ref: 10-F093489

2’-Deoxyuridine extrapure, 98%

CAS: 951-78-0

Formula: C₉H₁₂N₂O₅

Molecular weight: 228.20

Ref: SR-92627

2'-Deoxyuridine

CAS: 951-78-0

Please enquire for more information about 2'-Deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₉H₁₂N₂O₅

Purity: Min. 98 Area-%

Molecular weight: 228.2 g/mol

Ref: 3D-Q-200273

Trifluridine EP Impurity D

CAS: 951-78-0

Formula: C₉H₁₂N₂O₅

Molecular weight: 228.2

Ref: ST-EA-CP-T185004

2'-Deoxyuridine

CAS: 951-78-0

2'-Deoxyuridine (2'-dU) is an intermediate in the synthesis of thymidylate, which is a precursor for DNA synthesis. It can be prepared through high-performance liquid chromatography. 2'-dU has been shown to inhibit the enzymatic activity of enzymes responsible for synthesizing uridine and thymidylate, leading to neuronal death. 2'-dU has also been shown to have a protective effect against mitochondrial dysfunction induced by hydrogen fluoride. It is also known to bind with toll-like receptor 4 (TLR4), which is involved in inflammatory responses. 2'-dU has been used as a fluorescence probe for nucleic acids and as a polymerase chain reaction (PCR) substrate.

Formula: C₉H₁₂N₂O₅

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 228.21 g/mol

Ref: 3D-ND06282