CAS 960203-27-4

Vortioxetine hydrobromide

Description:

Vortioxetine hydrobromide is a pharmacological compound primarily used as an antidepressant. It functions as a serotonin modulator and stimulator, influencing various serotonin receptors and the reuptake of serotonin in the brain. This unique mechanism of action contributes to its efficacy in treating major depressive disorder. The substance is characterized by its molecular formula, which reflects its complex structure, and it typically appears as a white to off-white crystalline powder. Vortioxetine hydrobromide is soluble in water and exhibits stability under standard storage conditions. Its pharmacokinetics indicate a moderate half-life, allowing for once-daily dosing in clinical settings. Common side effects may include nausea, dizziness, and sexual dysfunction, which are important considerations in patient management. As with any medication, it is essential to monitor for potential interactions with other drugs and to assess individual patient responses to therapy. Overall, vortioxetine hydrobromide represents a significant advancement in the treatment of depression, offering a distinct approach compared to traditional antidepressants.

Formula: C₁₈H₂₂N₂S·HBr

InChI: InChI=1S/C18H22N2S.BrH/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20;/h3-8,13,19H,9-12H2,1-2H3;1H

InChI key: InChIKey=VNGRUFUIHGGOOM-UHFFFAOYSA-N

SMILES: S(C1=C(C=CC=C1)N2CCNCC2)C3=C(C)C=C(C)C=C3.Br

Synonyms:

• Lu AA 21004 hydrobromide
• Piperazine, 1-[2-[(2,4-dimethylphenyl)thio]phenyl]-, hydrobromide (1:1)
• Vortioxetine hydrobromide
• Vothiaxetine
• 1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine hydrobromide
• Vortioxetine (Lu AA21004) HBr
• 1-[2-(2,4-dimethylphenyl)sulfanylphenyl]piperazine hydrobromide
• Lu AA21004 (HBr)
• 1-[2-(2,4-Dimethyl-phenylsulfanyl)-phenyl]-piperazine, hydrobromid
• Vortioxetine HBr
• Vortioxetine (Lu AA21004) hydrobroMide

Vortioxetine.HBr

CAS: 960203-27-4

Color and Shape: Beige To Light Yellow

Ref: LP-VOX-1884-HB-10

Vortioxetine.HBr, 1mg/ml in Methanol (as free base)

CAS: 960203-27-4

Color and Shape: Colourless

Ref: LP-VOX-1884-HB-1LM

Vortioxetine Hydrobromide

CAS: 960203-27-4

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Formula: C₁₈H₂₂N₂S·HBr

Color and Shape: White Crystalline Powder

Molecular weight: 298.15037

Ref: 45-1718100

Vortioxetine hydrobromide

CAS: 960203-27-4

Formula: C₁₈H₂₃BrN₂S

Purity: 99%

Color and Shape: Solid

Molecular weight: 379.3576

Ref: IN-DA00IJQR

Vortioxetine hydrobromide

CAS: 960203-27-4

Vortioxetine hydrobromide

Purity: ≥98%

Molecular weight: 379.36g/mol

Ref: 54-BUP14125

1-(2-((2,4-Dimethylphenyl)Thio)Phenyl)Piperazine Hydrobromide

CAS: 960203-27-4

1-(2-((2,4-Dimethylphenyl)Thio)Phenyl)Piperazine Hydrobromide

Purity: 99%

Molecular weight: 379.36g/mol

Ref: 54-OR1024743

Vortioxetine hydrobromide

CAS: 960203-27-4

Formula: C₁₈H₂₃BrN₂S

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 379.36

Ref: 7W-GP3664

Vortioxetine HBr

CAS: 960203-27-4

Formula: C₁₈H₂₂N₂S·HBr

Color and Shape: Yellow Solid

Molecular weight: 298.45 80.91

Ref: 4Z-V-043037

Vortioxetine hydrobromide

CAS: 960203-27-4

Vortioxetine hydrobromide (Lu AA21004 hydrobromide) is a serotonin (5-HT) modulator and stimulator (SMS), inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50: 15/33

Formula: C₁₈H₂₂N₂S·HBr

Purity: 98.85% - 99.98%

Color and Shape: Solid

Molecular weight: 379.36

Ref: TM-T2395L

Vortioxetine Hydrobromide-D8

Controlled Product

CAS: 508233-74-7, 960203-27-4

Applications Vortioxetine Hydrobromide-D8 is deuterium labeled Vortioxetine Hydrobromide (V766000), a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References (1) Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011)(2) Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012) (3) Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)

Formula: C₁₈D₈H₁₄N₂S·BrH

Color and Shape: Off White Powder

Molecular weight: 387.4069

Ref: TR-V766002

Vortioxetine Hydrobromide

CAS: 960203-27-4

Applications Vortioxetine Hydrobromide is a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).
References (1) Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011)(2) Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012) (3) Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)

Formula: C₁₈H₂₂N₂S·BrH

Color and Shape: Beige To Light Yellow

Molecular weight: 379.358

Ref: TR-V766000

N-Nitroso-Vortioxetine-D8

CAS: 508233-74-7, 960203-27-4

Formula: C₁₈H₁₃D₈N₃OS

Color and Shape: Neat

Molecular weight: 335.49

Ref: TR-N991171

Vortioxetine hydrobromide

CAS: 960203-27-4

Purity: 97.0%

Color and Shape: Solid

Molecular weight: 379.3599853515625

Ref: 10-F468400

1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine hydrobromide

Controlled Product

CAS: 960203-27-4

1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine hydrobromide is an atypical antidepressant that is used for the treatment of major depressive disorder. It has been shown to be effective in animal models of depression and in clinical trials with humans. 1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine hydrobromide blocks the serotonin 5HT1B receptor subtype, which is responsible for regulating mood and emotional response. This drug does not block the 5HT1A or 5HT2 receptors, so it does not cause some of the side effects associated with selective serotonin reuptake inhibitors (SSRIs). In addition, 1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine hydrobromide has a chemical stability that lasts longer than other drugs in its class.

Formula: C₁₈H₂₂N₂S·HBr

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 379.36 g/mol

Ref: 3D-FD157097

Vortioxetine Hydrobromide (1 mg/mL in Methanol)

CAS: 960203-27-4

Formula: C₁₈H₂₂N₂S·BrH

Color and Shape: Single Solution

Molecular weight: 379.358

Ref: TR-KIT8230