CAS 97-67-6

L-Malic acid

Description:

L-Malic acid, with the CAS number 97-67-6, is a naturally occurring organic compound classified as a dicarboxylic acid. It is a colorless, odorless crystalline solid that is soluble in water and has a slightly tart flavor, commonly found in various fruits, particularly apples. L-Malic acid plays a crucial role in the Krebs cycle, a key metabolic pathway for energy production in living organisms. Its molecular formula is C4H6O5, and it features two carboxyl functional groups (-COOH), which contribute to its acidity and reactivity. L-Malic acid is used in the food industry as a flavoring agent and acidulant, enhancing the taste of beverages and candies. Additionally, it has applications in the cosmetic and pharmaceutical industries due to its ability to act as a pH regulator and a chelating agent. The compound is generally recognized as safe (GRAS) when used in food products, and its biodegradable nature makes it an environmentally friendly option in various applications.

Formula: C₄H₆O₅

InChI: InChI=1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1

InChI key: InChIKey=BJEPYKJPYRNKOW-REOHCLBHSA-N

SMILES: [C@H](CC(O)=O)(C(O)=O)O

Synonyms:

• (-)-(S)-Malic acid
• (-)-<span class="text-smallcaps">L</span>-Malic acid
• (-)-Hydroxysuccinic acid
• (-)-L-Malic acid
• (-)-Malic acid
• (2S)-2-Hydroxybutanedioic acid
• (2S)-2-Hydroxysuccinic acid
• (2S)-Malic acid
• (S)-2-Hydroxysuccinic acid
• <span class="text-smallcaps">L</span>-Apple acid
• Acide L-malique
• Apple acid
• Butanedioic acid, 2-hydroxy-, (2S)-
• Butanedioic acid, hydroxy-, (S)-
• L-Apfelsaure
• Malic Acid, L-
• Malic acid, <span class="text-smallcaps">L</span>-
• Nsc 9232
• S-2-Hydroxybutanedioic acid
• acido L-malico
• L-Hydroxysuccinic acid
• (S)-(-)-Hydroxysuccinic acid
• L-Maleic Acid
• (2S)-2-hydroxybutanedioate
• Butanedioic acid, hydroxy-, (2S)-
• (S)-HYDROXYBUTANEDIOIC ACID
• HYDROXYBUTANEDIOIC ACID
• L-(-)-APPLE ACID
• 1-HYDROXYSUCCINIC ACID
• L-HYDROXYBUTANEDIOIC ACID
• 2-HYDROXYSYCCINIC ACID
• (S)-2-HYDROXYBUTANEDICARBOXYLIC ACID
• L(-)-MALATE
• NATURAL APPLE ACID

L-(-)-Malic Acid

CAS: 97-67-6

Formula: C₄H₆O₅

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 134.09

Ref: 3B-M0022

L-Malic acid, &ge;99%

CAS: 97-67-6

Thermo Scientific L-Malic acid

Formula: C₄H₆O₅

Purity: 99%

Color and Shape: White crystalline powder

Molecular weight: 134.09

Ref: 02-J18700

L-(-)-Malic acid, 99%

CAS: 97-67-6

L-(-)-Malic acid is used as a food additive, Selective -amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including -opioid receptor agonists, 1,25-dihydroxyvitamin D3 analogue, and phoslactomycin B. This Thermo Scientific Chemicals brand

Formula: C₄H₆O₅

Purity: 99%

Color and Shape: White, Powder or crystals or crystalline powder

Molecular weight: 134.09

Ref: 02-J63221

L-(-)-Malic acid, 97%

CAS: 97-67-6

L-(-)-Malic acid is used as Selective -amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including -opioid rece. It also acts as active ingredient in many sour or tart foods. It is used as synthesizing disincrustant and fluorescent whiteni

Formula: C₄H₆O₅

Purity: 97%

Color and Shape: White, Crystals or powder or crystalline powder

Molecular weight: 134.09

Ref: 02-A13702

L-MALIC ACID CRS

CAS: 97-67-6

L-MALIC ACID CRS

Color and Shape: Added

Ref: 41-Y0002510

L-(-)-MALIC ACID

CAS: 97-67-6

Formula: C₄H₆O₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 134.0874

Ref: IN-DA003R6H

(S)-Malic acid

CAS: 97-67-6

(S)-Malic acid

Formula: C₄H₆O₅

Purity: ≥98%, 10 mM in DMSO

Molecular weight: 134.09

Ref: 54-BUP19715

L-Malic Acid

CAS: 97-67-6

Formula: C₄H₆O₅

Color and Shape: White To Off-White Solid

Molecular weight: 134.09

Ref: 4Z-M-185002

L-(-)-Malic acid, GlenCell™, suitable for cell culture

CAS: 97-67-6

Formula: C₄H₆O₅

Molecular weight: 134.09

Ref: 7W-GK0921

L-(-)-Malic acid

CAS: 97-67-6

Formula: C₄H₆O₅

Purity: (Titration) ≥ 99.0%

Color and Shape: White to almost white powder or crystals

Molecular weight: 134.09

Ref: 7W-GK8399

L-Malic acid

CAS: 97-67-6

Formula: C₄H₆O₅

Color and Shape: Neat

Molecular weight: 134.09

Ref: 04-C14730550

(S)-Malic acid (Standard)

CAS: 97-67-6

(S)-Malic acid (Standard) is the standard substance of (S)-Malic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a tart-tasting organic dicarboxylic acid that plays a role in many sour or tart foods. Apples contain malic acid, which contributes to the sourness of a green apple. Malic acid can make a wine taste tart, although the amount decreases with increasing fruit ripeness. (wikipedia). In its ionized form malic acid is called malate. Malate is an intermediate of the TCA cycle along with fumarate. It can also be formed from pyruvate as one of the anaplerotic reactions. In humans, malic acid is both derived from food sources and synthesized in the body through the citric acid cycle or Krebs cycle which takes place in the mitochondria. Malate's importance to the production of energy in the body during both aerobic and anaerobic conditions is well established. Under aerobic conditions, the oxidation of malate to oxaloacetate provides reducing equivalents to the mitochondria through the malate-aspartate redox shuttle. During anaerobic conditions, where a buildup of excess of reducing equivalents inhibits glycolysis, malic acid's simultaneous reduction to succinate and oxidation to oxaloacetate is capable of removing the accumulating reducing equivalents. This allows malic acid to reverse hypoxia's inhibition of glycolysis and energy production. In studies on rats it has been found that only tissue malate is depleted following exhaustive physical activity. Other key metabolites from the citric acid cycle needed for energy production were found to be unchanged. Because of this, a deficiency of malic acid has been hypothesized to be a major cause of physical exhaustion. Notably, the administration of malic acid to rats has been shown to elevate mitochondrial malate and increase mitochondrial respiration and energy production.

Formula: C₄H₆O₅

Molecular weight: 134.09

Ref: TM-TMSM-0015

(S)-Malic acid

CAS: 97-67-6

(S)-2-hydroxysuccinic acid

Formula: C₄H₆O₅

Purity: 98%

Molecular weight: 134.09

Ref: IN-DG23296

(S)-Malic acid

CAS: 97-67-6

(S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a naturally occurring dicarboxylic acid that is the source of the sweet and sour flavour of fruits.

Formula: C₄H₆O₅

Purity: 99.72% - 99.98%

Color and Shape: White Solid

Molecular weight: 134.09

Ref: TM-T4838

L-(-)-Malic acid

CAS: 97-67-6

L-(-)-Malic acid

Formula: C₄H₆O₅

Purity: 98%

Color and Shape: White Solid

Molecular weight: 134.08743

Ref: 54-OR51833

L-(-)-Malic Acid

CAS: 97-67-6

Applications The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B.
References Rindi, G., et al.: Biochem. J., 80, 214 (1961), Wolfgang, M., et al.: J. Biol. Chem., 281, 37265 (2006), Navarro, D., et al.: Metab. Brain Dis., 23, 115 (2008),

Formula: C₄H₆O₅

Color and Shape: Neat

Molecular weight: 134.09

Ref: TR-M159505

L-Malic acid

CAS: 97-67-6

Formula: C₄H₆O₅

Purity: 98%

Color and Shape: White crystalline powder

Molecular weight: 134.087

Ref: 10-F152310

L-Malic acid

CAS: 97-67-6

L-Malic acid is a dicarboxylic acid that is produced in plants and animals. It is an important intermediate in the citric acid cycle, which occurs in all aerobic organisms. L-Malic acid has many uses including as a building block for chemical synthesis, as a reagent for many different reactions, and as a speciality chemical. L-Malic acid is also used in the manufacture of pharmaceuticals and other chemicals. CAS No.: 97-67-6

Formula: C₄H₆O₅

Molecular weight: 134.09 g/mol

Ref: 3D-M-0850

L-(-)-Malic acid

CAS: 97-67-6

L-malic acid is a naturally occurring organic compound that can be found in many fruits and vegetables. It is an important intermediate in the citric acid cycle as well as a key component of the Krebs cycle. L-malic acid has been shown to have antiseizure and anti-inflammatory effects, and also inhibits the growth of bacteria such as Staphylococcus aureus. L-malic acid is synthesized from sodium carbonate and lactic acid by reacting with a mineral acid such as hydrochloric, sulfuric, or nitric acid. This reaction produces hydrogen gas, water, and l-malic acid. L-Malic Acid is also used for production of monoclonal antibodies against various targets, including human cells.

Formula: C₄H₆O₅

Color and Shape: White Off-White Powder

Molecular weight: 134.09 g/mol

Ref: 3D-FM25004