CAS 98079-52-8: Lomefloxacin hydrochloride
Description:Lomefloxacin hydrochloride is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily used to treat various bacterial infections, particularly those affecting the urinary tract and respiratory system. The compound exhibits a mechanism of action that involves the inhibition of bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and repair. Lomefloxacin hydrochloride is typically administered orally and is well-absorbed in the gastrointestinal tract. Its solubility in water is moderate, which influences its bioavailability. The substance is known for its potential side effects, including gastrointestinal disturbances, central nervous system effects, and, in rare cases, tendon damage. As with other fluoroquinolones, caution is advised in patients with a history of tendon disorders or those taking corticosteroids. The chemical structure includes a bicyclic core with a fluorine atom, contributing to its potency and spectrum of activity. Overall, Lomefloxacin hydrochloride is an important therapeutic agent in the management of bacterial infections, although its use must be carefully monitored to mitigate potential adverse effects.
Formula:C17H19F2N3O3·ClH
InChI:InChI=1S/C17H19F2N3O3.ClH/c1-3-21-8-11(17(24)25)16(23)10-6-12(18)15(13(19)14(10)21)22-5-4-20-9(2)7-22;/h6,8-9,20H,3-5,7H2,1-2H3,(H,24,25);1H
InChI key:InChIKey=KXEBLAPZMOQCKO-UHFFFAOYSA-N
SMILES:Cl.O=C(O)C1=CN(C2=C(F)C(=C(F)C=C2C1=O)N3CCNC(C)C3)CC
- Synonyms:
- 1-Ethyl-6,8-Difluoro-7-(3-Methylpiperazin-1-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid Hydrochloride (1:1)
- 1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid hydrochloride
- 3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, hydrochloride (1:1)
- 3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, monohydrochloride
- Alkaflox
- Bareon
- Chimono
- Lomebact
- Lomef 400
- Lomefloxacin hcl
- See more synonyms
- Lomflox
- Lomitas
- Lomoxin
- Maxaquin
- Mazaquin
- Ny 198
- Orchacin
- Sc 47111
- Uniquin
- Lomefloxacin hydrochloride
