CAS 98105-99-8

Sarafloxacin

Description:

Sarafloxacin is a synthetic fluoroquinolone antibiotic that is primarily used in veterinary medicine, particularly for treating bacterial infections in livestock and poultry. It exhibits broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. Sarafloxacin is characterized by its chemical structure, which includes a bicyclic core and a fluorine atom that enhances its potency and spectrum of activity. The compound is typically administered orally and is known for its relatively high bioavailability. Its pharmacokinetics involve rapid absorption and distribution, with a moderate half-life, allowing for effective treatment regimens. However, the use of sarafloxacin has raised concerns regarding antibiotic resistance and its potential impact on human health, leading to regulatory scrutiny in some regions. As with other antibiotics, appropriate usage is essential to mitigate the development of resistant bacterial strains.

Formula: C₂₀H₁₇F₂N₃O₃

InChI: InChI=1S/C20H17F2N3O3/c21-12-1-3-13(4-2-12)25-11-15(20(27)28)19(26)14-9-16(22)18(10-17(14)25)24-7-5-23-6-8-24/h1-4,9-11,23H,5-8H2,(H,27,28)

InChI key: InChIKey=XBHBWNFJWIASRO-UHFFFAOYSA-N

SMILES: O=C1C=2C(N(C=C1C(O)=O)C3=CC=C(F)C=C3)=CC(=C(F)C2)N4CCNCC4

Synonyms:

• 3-Quinolinecarboxylic Acid, 6-Fluoro-1-(4-Fluorophenyl)-1,4-Dihydro-4-Oxo-7-(1-Piperazinyl)-
• 6-Fluoro-1-(4-Fluorophenyl)-4-Oxo-7-(Piperazin-1-Yl)-1,4-Dihydroquinoline-3-Carboxylic Acid
• 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
• 98105-99-8
• A 56620
• Pd 121960
• Sarafloxacin

Sarafloxacin Hydrochloride

CAS: 91296-87-6, 98105-99-8

Formula: C₂₀H₁₇F₂N₃O₃·HCl

Purity: >97.0%(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 421.83

Ref: 3B-S0840

Sarafloxacin

CAS: 98105-99-8

Formula: C₂₀H₁₇F₂N₃O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 385.3641

Ref: IN-DA00H5SQ

Sarafloxacin

CAS: 98105-99-8

Sarafloxacin

Purity: ≥95%

Molecular weight: 385.36g/mol

Ref: 54-BUP17109

Sarafloxacin

CAS: 98105-99-8

Formula: C₂₀H₁₇F₂N₃O₃

Molecular weight: 385.36

Ref: 7W-GP7127

Sarafloxacin

CAS: 98105-99-8

Applications Sarafloxacin is a quinolone antibiotic drug that was discontinued in 2001. Useful for biological studies and can be detected with colloidal gold test strips. References Jia, F., et al.: Agric. Biotechnol., 8, 172 (2019)

Formula: C₂₀H₁₇F₂N₃O₃

Color and Shape: Light Yellow

Molecular weight: 385.36

Ref: TR-S139503

Sarafloxacin

CAS: 98105-99-8

Sarafloxacin is an antimicrobial agent that belongs to the quinolone class. It has a chemical stability that allows for use in an injection solution, which may be useful for treating infectious diseases. Sarafloxacin has been shown to be active against human pathogens such as Haemophilus influenzae and Neisseria meningitides. This drug also shows activity against other human pathogens such as Streptococcus pneumoniae, Chlamydia pneumoniae, and Mycoplasma pneumoniae. Sarafloxacin inhibits bacterial growth by acting on DNA gyrase, a type II topoisomerase, and RNA polymerase. The fluorescence detector detects fluorescence emitted from sarafloxacin-treated cells in the presence of two different wavelengths of light. This method is used in conjunction with LC-MS/MS to identify the antibiotic’s molecular targets and determine its mechanism of action.

Formula: C₂₀H₁₇F₂N₃O₃

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 385.36 g/mol

Ref: 3D-FS38236

Sarafloxacin

CAS: 98105-99-8

Formula: C₂₀H₁₇F₂N₃O₃

Purity: 98%

Molecular weight: 385.371

Ref: 10-F324699

Sarafloxacin

CAS: 98105-99-8

Sarafloxacin (A56620) has antibacterial activities against Gram-positive and Gram-negative bacteria.

Formula: C₂₀H₁₇F₂N₃O₃

Purity: 98.07% - 98.94%

Color and Shape: Solid

Molecular weight: 385.36

Ref: TM-T20774