CAS 985-12-6

Drotaverine hydrochloride

Description:

Drotaverine hydrochloride is a synthetic antispasmodic agent primarily used to relieve smooth muscle spasms in various conditions, such as gastrointestinal and biliary colic. It is a derivative of isoquinoline and functions by inhibiting phosphodiesterase, leading to increased levels of cyclic adenosine monophosphate (cAMP) in smooth muscle cells, which results in muscle relaxation. The substance is typically administered orally or via injection, and it is known for its rapid onset of action. Drotaverine hydrochloride is characterized by its white to off-white crystalline powder form, which is soluble in water and alcohol but insoluble in organic solvents. Its chemical formula reflects its molecular structure, and it has a relatively low toxicity profile, making it suitable for use in various therapeutic applications. Common side effects may include nausea, dizziness, or allergic reactions, though these are generally mild. Overall, Drotaverine hydrochloride is an effective medication for managing spasmodic pain and improving patient comfort in clinical settings.

Formula: C₂₄H₃₁NO₄·ClH

InChI: InChI=1S/C24H31NO4.ClH/c1-5-26-21-10-9-17(14-22(21)27-6-2)13-20-19-16-24(29-8-4)23(28-7-3)15-18(19)11-12-25-20;/h9-10,13-16,25H,5-8,11-12H2,1-4H3;1H

InChI key: InChIKey=JBFLYOLJRKJYNV-UHFFFAOYSA-N

SMILES: C(=C1C=2C(=CC(OCC)=C(OCC)C2)CCN1)C3=CC(OCC)=C(OCC)C=C3.Cl

Synonyms:

• (1E)-1-[(3,4-diethoxyphenyl)methylidene]-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
• 1,2,3,4-Tetrahydro-6,7-diethoxy-1-((3,4-diethoxyphenyl)methylene)-isoquinoline hydrochloride
• 1-(3,4-Diethoxy-benzylidene)-6,7-diethoxy-1,2,3,4-tetrahydro-isoquinoline; hydrochloride
• Drotaverin hydrochloride
• Drotaverine hcl
• Drotaverinium chloride
• Drotin
• Isodihydroperparine hydrochloride
• Isoquinoline, 1-(3,4-diethoxybenzylidene)-6,7-diethoxy-1,2,3,4-tetrahydro-, hydrochloride
• Isoquinoline, 1-[(3,4-diethoxyphenyl)methylene]-6,7-diethoxy-1,2,3,4-tetrahydro-, hydrochloride
• Isoquinoline, 1-[(3,4-diethoxyphenyl)methylene]-6,7-diethoxy-1,2,3,4-tetrahydro-, hydrochloride (1:1)
• No-Spa
• No-Spa hydrochloride
• Nosh-Bra

Drotaverine hydrochloride

CAS: 985-12-6

Formula: C₂₄H₃₂ClNO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 433.9682

Ref: IN-DA006RWE

Drotaverine HCl

CAS: 911-60-4, 985-12-6

Formula: C₂₄H₃₁NO₄·HCl

Color and Shape: Pale Yellow Solid

Molecular weight: 397.52 36.46

Ref: 4Z-D-088001

Drotaverine hydrochloride

CAS: 985-12-6

Drotaverine hydrochloride

Purity: ≥98%

Molecular weight: 433.968g/mol

Ref: 54-BUP13572

Drotaverine hydrochloride

CAS: 985-12-6

Formula: C₂₄H₃₁NO₄

Purity: ≥ 95%

Color and Shape: White to off-white or yellow powder

Molecular weight: 397.51

Ref: 7W-GP2082

Drotaverine Hydrochloride

CAS: 985-12-6

Formula: C₂₄H₃₁NO₄·HCl

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light orange to Pale yellow green powder to crystal

Molecular weight: 433.97

Ref: 3B-D6205

Drotaverine hydrochloride

CAS: 985-12-6

Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor，and is an antispasmodic drug, used to enhance cervical dilation

Formula: C₂₄H₃₂ClNO₄

Purity: 99.81%

Color and Shape: Pale-Yellow Crystalline Solid

Molecular weight: 433.968

Ref: TM-T8787

Drotaverine Hydrochloride

Controlled Product

CAS: 985-12-6

Applications Analogue of Papaverine. Antispasmodic.
References Lalla, J., et al.: J. Pharm. Biomed. Anal., 11, 385 (1993), Bolaji, O.O., et al.: Eur. J. Drug Metab. Pharmacokinet., 21, 217 (1996), Kraemer, T., et al.: Drug Metab. Dispos., 28, 339 (2000)

Formula: C₂₄H₃₁NO₄·ClH

Color and Shape: Neat

Molecular weight: 433.97

Ref: TR-D689700

Drotaverine hydrochloride

CAS: 985-12-6

Purity: 99.48%

Molecular weight: 433.97

Ref: 10-F979071

Drotaverine HCl - Bio-X ™

CAS: 985-12-6

Drotaverine is an antispasmodic drug that is used to alleviate gastrointestinal and genitourinary smooth muscle spasms. This drug works by inhibiting phosphodiesterase-4 and increasing levels of cAMP leading to smooth muscle relaxation.

Formula: C₂₄H₃₁NO₄•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 433.97 g/mol

Ref: 3D-BD164396

Drotaverine hydrochloride

CAS: 985-12-6

Phosphodiesterase 4 inhibitor; anti-spasmodic agent

Formula: C₂₄H₃₂ClNO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 433.97 g/mol

Ref: 3D-FD22624

Drotaverine-d10 Hydrochloride

Controlled Product

CAS: 985-12-6

Formula: C₂₄H₂₂D₁₀ClNO₄

Color and Shape: Neat

Molecular weight: 444.03

Ref: TR-D689702