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CAS 985-12-6

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Drotaverine hydrochloride

Description:
Drotaverine hydrochloride is a synthetic antispasmodic agent primarily used to relieve smooth muscle spasms in various conditions, such as gastrointestinal and biliary colic. It is a derivative of isoquinoline and functions by inhibiting phosphodiesterase, leading to increased levels of cyclic adenosine monophosphate (cAMP) in smooth muscle cells, which results in muscle relaxation. The substance is typically administered orally or via injection, and it is known for its rapid onset of action. Drotaverine hydrochloride is characterized by its white to off-white crystalline powder form, which is soluble in water and alcohol but insoluble in organic solvents. Its chemical formula reflects its molecular structure, and it has a relatively low toxicity profile, making it suitable for use in various therapeutic applications. Common side effects may include nausea, dizziness, or allergic reactions, though these are generally mild. Overall, Drotaverine hydrochloride is an effective medication for managing spasmodic pain and improving patient comfort in clinical settings.
Formula:C24H31NO4·ClH
InChI:InChI=1S/C24H31NO4.ClH/c1-5-26-21-10-9-17(14-22(21)27-6-2)13-20-19-16-24(29-8-4)23(28-7-3)15-18(19)11-12-25-20;/h9-10,13-16,25H,5-8,11-12H2,1-4H3;1H
InChI key:InChIKey=JBFLYOLJRKJYNV-UHFFFAOYSA-N
SMILES:C(=C1C=2C(=CC(OCC)=C(OCC)C2)CCN1)C3=CC(OCC)=C(OCC)C=C3.Cl
Synonyms:
  • (1E)-1-[(3,4-diethoxyphenyl)methylidene]-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
  • 1,2,3,4-Tetrahydro-6,7-diethoxy-1-((3,4-diethoxyphenyl)methylene)-isoquinoline hydrochloride
  • 1-(3,4-Diethoxy-benzylidene)-6,7-diethoxy-1,2,3,4-tetrahydro-isoquinoline; hydrochloride
  • Drotaverin hydrochloride
  • Drotaverine hcl
  • Drotaverinium chloride
  • Drotin
  • Isodihydroperparine hydrochloride
  • Isoquinoline, 1-(3,4-diethoxybenzylidene)-6,7-diethoxy-1,2,3,4-tetrahydro-, hydrochloride
  • Isoquinoline, 1-[(3,4-diethoxyphenyl)methylene]-6,7-diethoxy-1,2,3,4-tetrahydro-, hydrochloride
  • See more synonyms
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