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CAS 985-16-0

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Nafcillin sodium

Description:
Nafcillin sodium is a semi-synthetic penicillin antibiotic that is primarily used to treat infections caused by penicillinase-producing staphylococci. It is characterized by its ability to resist degradation by certain beta-lactamase enzymes, which makes it effective against specific strains of bacteria. Nafcillin sodium is typically administered via injection and is soluble in water, allowing for easy preparation of injectable solutions. The compound has a molecular formula that reflects its structure, which includes a beta-lactam ring, a thiazolidine ring, and a side chain that contributes to its antibacterial properties. Its mechanism of action involves inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Nafcillin sodium is generally well-tolerated, but like all antibiotics, it can cause side effects, including allergic reactions and gastrointestinal disturbances. It is important to use this antibiotic judiciously to prevent the development of antibiotic resistance. As with any medication, it should be prescribed and monitored by a healthcare professional.
Formula:C21H22N2O5S·Na
InChI:InChI=1S/C21H22N2O5S.Na/c1-4-28-13-10-9-11-7-5-6-8-12(11)14(13)17(24)22-15-18(25)23-16(20(26)27)21(2,3)29-19(15)23;/h5-10,15-16,19H,4H2,1-3H3,(H,22,24)(H,26,27);/t15-,16+,19-;/m1./s1
InChI key:InChIKey=FZWUJBMAAITKNH-FRFVDRIFSA-N
SMILES:C(O)(=O)[C@@H]1N2[C@@]([C@H](NC(=O)C=3C4=C(C=CC3OCC)C=CC=C4)C2=O)(SC1(C)C)[H].[Na]
Synonyms:
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(2-ethoxy-1-naphthamido)-3,3-dimethyl-7-oxo-, monosodium salt
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2-ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, monosodium salt, [2S-(2α,5α,6β)]-
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2-ethoxy-1-naphthalenyl)carbonyl]amino]-3,3-dimethyl-7-oxo-, sodium salt (1:1), (2S,5R,6R)-
  • 6-(2-Ethoxy-1-naphthamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt
  • 6-(2-Ethoxy-1-naphthamido)penicillin sodium salt
  • Brl 1383
  • Nafcil
  • Nafcillin sodium
  • Nafcillin sodium salt
  • Naftopen
  • See more synonyms
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