Amino Acid Derivatives

FA-Phe-Gly-Gly-OH is a peptide with angiotensin II inhibitory properties. It has been shown that FA-Phe-Gly-Gly-OH inhibits the enzyme activity of angiotensin converting enzyme (ACE) and prevents the formation of angiotensin II, which causes blood vessel constriction. The inhibitory effects of FA-Phe-Gly-Gly-OH on ACE are reversible and competitive, which is different from other ACE inhibitors that are irreversible and noncompetitive. This peptide also has antioxidative properties, due to its ability to scavenge reactive oxygen species (ROS). This peptide can be hydrolysed by esterases or proteases in vitro or in vivo.

Z-Arg-Leu-Arg-Gly-Gly-AMC acetate is a protease inhibitor that blocks the activity of the proteasome. It has been shown to inhibit the activity of histidine proteases and to inhibit proteolysis by the proteasome in a kinetic assay. This inhibitor also inhibits coronavirus replication, which may be due to its ability to bind to histidine residues on proteins involved in viral replication. Z-Arg-Leu-Arg-Gly-Gly-AMC acetate is expressed in transfected cells as an enzyme with a polymerase chain reaction (PCR) product and has been shown to prevent viral replication.

Amino acid; precursor to neurotransmitters, hormones, pigments, natural phenols

M06246 - Fmoc-Gly-OPfp

M03000 - H-Asp-OH

DL-Cysteine is a naturally occurring amino acid that is found in human cells and other living organisms. It has been shown to have antioxidant properties. DL-Cysteine has also been shown to be a cofactor for enzymes that synthesize proteins, DNA, and RNA. DL-Cysteine may also have the ability to regulate cellular iron homeostasis through its effects on the expression of genes that play a role in this process. This amino acid can also inhibit molecules that are involved in protein oxidation and provide biochemical properties for use as research tools.

Boc-Phe-Pro-OH is an opioid receptor agonist. It binds to the δ opioid receptors and activates them, which leads to analgesic effects. Boc-Phe-Pro-OH also has antibacterial properties and can be used for the treatment of bacterial infections. This compound may also have antiinflammatory properties that are mediated by its ability to inhibit prostaglandin synthesis. Boc-Phe-Pro-OH has been shown to possess a high affinity for the μ opioid receptor, but does not activate this receptor subtype.

L-Alaninol is a natural amino acid that can be synthesized in an asymmetric way. It has been used as a palladium complex catalyst to produce the inorganic acid, l-alaninol. L-Alaninol is biologically active and has shown antiviral and antimicrobial activities against mycobacterium avium and human lymphocytes. It also has been shown to have anticancer properties in animal models. In addition, it has been used as a model system for the study of organic chemistry reactions. L-Alaninol has also been shown to exhibit magnetic resonance spectroscopy properties that are similar to those of l-phenylalaninol.

L-Homoglutamine is a non-essential amino acid that is an important part of the urea cycle. It also plays a role in protein synthesis, as well as in transfer reactions, such as the conversion of ammonia to urea. L-Homoglutamine has been shown to be an inhibitor of binding to collagenase, which may have therapeutic applications for diseases such as rheumatoid arthritis. This amino acid has been used in enzyme preparations and has been found to have biological properties that are similar to those of other carbonyl amino acids (e.g., L-glutamic acid).

D-Alanine methyl ester HCl is a diamide with antimycobacterial activity. It was synthesized by the reaction of D-alanine and methyl acrylate in the presence of methanesulfonic acid. The chiral compound was obtained as a racemic mixture. Optical properties are not reported.

Boc-L-histidine is a histidine derivative with a boronic acid group that can be used to synthesize imines. It is an organic solvent and can be used in magnetic resonance spectroscopy. Boc-L-histidine has been shown to inhibit the tyrosine activity of tyrosinase, which is involved in melanin synthesis. This compound also inhibits cancer cells by inhibiting the cellular process of protein synthesis and, as such, may be useful for the treatment of cancers.

Boc-Lys-OMe HCl is an ester hydrochloride of N-Boc-Lysine. It is a macrocyclic compound that has been used in the laboratory as an acidifying agent to convert sodium borohydride to methyl ester hydrochloride. Boc-Lys-OMe HCl is also used in the synthesis of macrocyclic compounds, such as n-boc-l-lysine and other polyamino compounds.

Fmoc-Thr(tBu)-Ser(Psi(Me,Me)pro)-OBzl is a high quality, research chemical that is used as an intermediate in the synthesis of complex compounds. It is a useful building block and can be used to make speciality chemicals. This reagent has many uses including being a useful scaffold for organic synthesis and a reaction component in the production of other fine chemicals. Fmoc-Thr(tBu)-Ser(Psi(Me,Me)pro)-OBzl has CAS No. 7791-02-8 and may be found in the following chemical structure:

Beta-cyano-l-alanine is a naturally occurring amino acid that is found in plants. It is synthesized by the enzyme beta-cyanoalanine synthase and is involved in plant metabolism. Beta-cyano-l-alanine is a precursor of the neurotransmitter gamma aminobutyric acid, or GABA, which has been shown to regulate the opening and closing of calcium channels in brain cells. In addition, it has been shown to inhibit enzymes such as phosphofructokinase and pyruvate kinase that are involved in the breakdown of glucose and other nutrients. Beta-cyano-l-alanine has also been shown to inhibit ryanodine receptors and other enzymes involved in muscle contraction. This amino acid can be used as an indicator for tissue culture experiments because it can be detected by sephadex G-100 chromatography.

(R)-(-)-2-Phenylglycinol is an enantiopure chiral compound that has been used in the synthesis of polymers. This polymerase chain reaction (PCR) inhibitor binds to the α subunit of DNA polymerase, preventing replication and transcription. The binding site for this inhibitor is located at the active site of the enzyme and is a hydroxyl group. The (S)-enantiomer of 2-phenylglycinol does not bind to the α subunit, so it can be used as a control in experiments. 2-Phenylglycinol is also known to have antiviral properties against HIV infection.

Building block

Pro-Gly-OH is a cyclic peptide that has been shown to have antimicrobial activity. Pro-Gly-OH has been shown to be an intramolecular hydrogen acceptor, which leads to the formation of a carbonyl group. This compound also has site specific interactions with the cell membrane and is taken up by cells. It is active at acidic pHs and can be activated by growth factors.
The conformational properties of Pro-Gly-OH are due to hydrogen bonding interactions and amide bond formation.

Z-O-tert-Butyl-L-tyrosine is a fine chemical that is soluble in water and has a wide range of uses. It is a versatile scaffold for the synthesis of complex compounds, and can be used as a building block or reaction component in research chemicals. Z-O-tert-Butyl-L-tyrosine is an important reagent for organic synthesis, especially when combined with other chemicals. This chemical can also be used as a speciality chemical to produce high quality products.

DL-Leucine is an amino acid that is needed for the formation of proteins. It is also able to inhibit the activity of enzymes by hydrolyzing them. DL-Leucine has been shown to be a potent inhibitor of lysine hydrolases and can be used as an additive in the manufacture of animal feed. DL-Leucine has been shown to be stable in many environments, including those containing chlorine, hydrochloric acid, n-dimethyl formamide, and x-ray crystallography. The enantiomers of DL-leucine have different chemical stability; one form is more stable than the other in acidic environments.

D-Phenylalanine is an amino acid that is found in the human body and is used as a pharmacological agent. It has been shown to be an antimicrobial peptide with a broad spectrum of activity against bacteria, yeast, and fungi. D-Phenylalanine also has the ability to inhibit the production of peptide hormones, such as gastrin and vasopressin, and can be used as an inhibitor for enzymes such as acetylcholine esterase. Studies have shown that D-phenylalanine can increase mitochondrial membrane potential in cells by binding to ester hydrochloride. This leads to increased enzyme activities, which may result in a decrease in hydrogen bonding interactions.

Boc-4-(aminomethyl)-L-phenylalanine is a useful building block in research and development of pharmaceuticals, agricultural chemicals, and other chemical products. It is a versatile intermediate that can be used in the production of many types of organic compounds. Boc-4-(aminomethyl)-L-phenylalanine has been used as a reagent for the preparation of various complex compounds and a reaction component in organic synthesis. It is also used to produce fluoroquinolones and other antibiotics. CAS No.: 137452-49-4

Applications H-Lys-Arg-OH acetate salt (CAS# 29586-66-1) is a useful research chemical compound.

Applications A cyclic peptide, one of the secondary metabolite of a mangrove endophytic fungus (No. 1947) from the South China Sea.
References Carmichael, J., et al.: Cancer Res., 47, 936 (1987), Blunt, J., et al.: Nat. Prod. Rep., 20, 1 (2003), Mitova, M., et al.: J. Nat. Prod., 67, 1178 (2004),

Applications Fmoc-L-Leu-OH-d10 is the labeled analogue of Fmoc-L-Leu-OH (F625015), an amino acid derivative, used in peptide chemistry. It is also one of the novel PPARγ ligands that can activate PPARγ in different ways, that reduces osteoclasts differentiation, and thus are better therapeutic targets in diabetes than traditional antidiabetic drugs.
References Haochen, W., et al.: J. Cell. Biochem., 114, 1969 (2013)