Angiogenesis
Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.
Subcategories of "Angiogenesis"
- BTK(166 products)
- Bcr-Abl(118 products)
- EGFR(582 products)
- FAK(72 products)
- FLT(86 products)
- Fibroblast Growth Factor Receptor (FGFR)(180 products)
- JAK(243 products)
- PDGFR(129 products)
- RAAS(89 products)
- Src(82 products)
- Syk(37 products)
- Thrombin(57 products)
- VDA(2 products)
- VEGFR(242 products)
Show 6 more subcategories
Found 2382 products of "Angiogenesis"
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FGFR-IN-13
CAS:FGFR-IN-13 (compound III-30), an irreversible covalent inhibitor of the fibroblast growth factor receptor (FGFR), effectively modulates signaling through FGFR1 (IC 50 = 0.20 ± 0.02 nM) and FGFR4 (IC 50 = 0.40 ± 0.03 nM). It suppresses the expression of crucial proteins such as total-PARP and Bcl-2, while enhancing the expression of Cleaved-PARP and Bax in a dose-dependent manner. Notably, FGFR-IN-13 demonstrates considerable antitumor and oral activity [1].Formula:C23H21N5O3Molecular weight:415.44Zotiraciclib HCl
CAS:Zotiraciclib (TG02/SB1317) is a CDK/JAK2/FLT3 inhibitor potentially treating Myc-overexpressing cancers, including glioblastoma.Formula:C23H26Cl2N4OColor and Shape:SolidMolecular weight:445.388AMG-Tie2-1
CAS:AMG-Tie2-1 is a Tie2 and VEGFR2 inhibitor with anticancer and antitumor activity for the study of cardiovascular disease and cancer.Formula:C25H20F3N5O2Purity:98.9%Color and Shape:SolidMolecular weight:479.45Infigratinib phosphate
CAS:Infigratinib phosphate (BGJ-398 phosphate) is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, andFormula:C26H34Cl2N7O7PPurity:99.24% - 99.6%Color and Shape:SolidMolecular weight:658.47AC430
CAS:AC430, a specific JAK2 inhibitor for cancer and autoimmune therapy, excels in preclinical trials with low doses. Developed by Ambit.Formula:C19H16FN5OColor and Shape:SolidMolecular weight:349.36Aminoquinuride
CAS:Surfen, or Aminoquinuride, reduces inflammation but blocks remyelination in MS mouse models and regulates murine T cell activation.Formula:C21H20N6OColor and Shape:SolidMolecular weight:372.42HKI-357 dimaleate
CAS:HKI-357 dimaleate is an irreversible dual inhibitor of EGFR and ERBB2. HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation.Formula:C39H37ClFN5O11Color and Shape:SolidMolecular weight:806.2Spebrutinib besylate
CAS:Spebrutinib besylate (AVL-292 benzenesulfonate; CC-292 besylate) is a Btk kinase activity inhibitor (IC50<0.5 nM, Kinact/Ki=7.69×104 M-1s-1s).Formula:C28H28FN5O6SPurity:98%Color and Shape:SolidMolecular weight:581.62EGFR T790M/L858R-IN-5
CAS:EGFR T790M/L858R-IN-5 (example 52) functions as a potent EGFR T790M/L858R inhibitor, demonstrating a 92.9% inhibition rate at a concentration of 0.05 μM [1].Formula:C28H31N9OMolecular weight:509.61AG-13958 monohydrochloride
CAS:AG-13958 monohydrochloride, a VEGFA inhibitor, may treat neovascular AMD to prevent rapid vision loss.Formula:C26H23ClFN7OColor and Shape:SolidMolecular weight:503.96c-ABL-IN-4
CAS:c-ABL-IN-4 is a potent inhibitor of c-Abl.Formula:C18H11ClF3N3O3Color and Shape:SolidMolecular weight:409.75c-ABL-IN-3
CAS:c-ABL-IN-3, from patent WO2021048567A1, is a potent c-Abl inhibitor for researching ALS, PD, and cancer.Formula:C17H11F3N4O3Color and Shape:SolidMolecular weight:376.29CGP52411
CAS:CGP52411 is an orally active, and ATP-competitive inhibitor of EGFR (IC50: 0.3 μM).Formula:C20H15N3O2Purity:99.78%Color and Shape:SolidMolecular weight:329.35JAK3/BTK-IN-1
CAS:JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two importantFormula:C25H28N8OPurity:97.89%Color and Shape:SolidMolecular weight:456.54SD-1029
CAS:SD-1029 is a JAK2 inhibitor and a novel Stat3 activation inhibitor that inhibits Stat3 phosphorylation and JAK-STAT signaling.Formula:C25H32Br2Cl2N2O3Color and Shape:SolidMolecular weight:639.25CHMFL-BTK-01
CAS:CHMFL-BTK-01 is an irreversible inhibitor of BTK (IC50: 7 nM) and also potently inhibits BTK Y223 auto-phosphorylation.Formula:C38H41N5O5Purity:98%Color and Shape:SolidMolecular weight:647.76JAK1-IN-4
CAS:JAK1-IN-4 selectively blocks JAK1 (IC50 = 85 nM) over JAK2/JAK3 and halts STAT3 phosphorylation in NCI-H 1975 cells (IC50 = 227 nM).Formula:C26H32FN9O2Purity:98%Color and Shape:SolidMolecular weight:521.59JAK3-IN-1
CAS:JAK3-IN-1 is an orally active, selective and potent JAK3 inhibitor for the study of immune system disorders.Formula:C26H30ClN7O2Color and Shape:SolidMolecular weight:508.02Ansornitinib
CAS:Ansornitinib (ANG-3070) is a KDR and PDGF receptor inhibitor with antifibrotic activity for the study of diseases caused by abnormal or excessive fibrosis.Formula:C30H32N6O4Purity:99.24%Color and Shape:SolidMolecular weight:540.61AC710
CAS:AC710 is a potent PDGFR inhibitor (Kds: 0.6, 1, 1.57, 1.3, 1 nM for FLT3, KIT, CSF1R, PDGFRα and PDGFRβ).Formula:C31H42N6O4Purity:99.67%Color and Shape:SolidMolecular weight:562.7JAK-IN-30
CAS:JAK-IN-30 (compound 31) is a water-soluble inhibitor of Janus kinases (JAKs), demonstrating inhibitory potency with half-maximal inhibitory concentration (IC50Formula:C19H26N8SPurity:98%Color and Shape:SolidMolecular weight:398.53KBP-7018
CAS:KBP-7018 is a selective TKI targeting c-KIT, RET, and PDGFR for mechanistic studies of fibrotic signaling and kinase-driven diseases.Formula:C31H30N4O5Purity:99.73%Color and Shape:SolidMolecular weight:538.59AN-019
CAS:AN-019 (NRC-019) is a Bcr-Abl kinase inhibitor with antitumor activity for the study of chronic myelogenous leukemia (CML) and breast cancer.Formula:C25H17F6N5OPurity:98.99%Color and Shape:SolidMolecular weight:517.43ALK-IN-5
CAS:ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK, IC50: 2.9 nM).Formula:C24H25FN6O3Purity:98%Color and Shape:SolidMolecular weight:464.49ALK2-IN-2
CAS:ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) (IC50: 9 nM), inhibiting ALK2 700-fold more than ALK3.Formula:C28H27N5O2SPurity:99.86%Color and Shape:SolidMolecular weight:497.61Ref: TM-T10287
1mg44.00€5mg89.00€10mg142.00€25mg216.00€50mg298.00€100mg411.00€200mg560.00€1mL*10mM (DMSO)99.00€Epertinib
CAS:Epertinib is a reversible and selective tyrosine kinase inhibitor of EGFR, HER2, and HER4 (IC50s: 1.48 nM, 7.15 nM, and 2.49 nM).Formula:C30H27ClFN5O3Purity:98%Color and Shape:SolidMolecular weight:560.02SSR128129E free acid
CAS:SSR128129E free acid is an orally available and allosteric inhibitor of FGFR(IC50 of 1.9 μM for FGFR1).Formula:C18H16N2O4Purity:98%Color and Shape:SolidMolecular weight:324.33JAK-IN-21
CAS:JAK-IN-21 is a selective and potent JAK inhibitor that inhibits JAK1, JAK2, J2V617F and TYK2 with IC50 values of 1.73, 2.04, 109 and 62.9 nM, respectively.Formula:C19H16N8OPurity:99.87%Color and Shape:SolidMolecular weight:372.38PF-06658607
CAS:PF-06658607 is an alkynylated irreversible Brutons tyrosine kinase (BTK) inhibitor.Formula:C27H24N6O2Color and Shape:SolidMolecular weight:464.52GW 583340 dihydrochloride
CAS:GW 583340 dihydrochloride is a potent and orally available dual EGFR/ErbB2 inhibitor and inhibits 80% of tumor growth in a mouse xenograft mode.Formula:C28H27Cl3FN5O3S2Purity:98.80%Color and Shape:SolidMolecular weight:671.03JAK3i
CAS:JAK3i selectively inhibits JAK3 kinase, targeting the second, vital wave of STAT5 phosphorylation for T cell growth.Formula:C18H15FN4O3Purity:98.61% - 99.81%Color and Shape:SolidMolecular weight:354.34JAK-IN-11
CAS:JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment.Formula:C23H22FN5O4SPurity:99.75%Color and Shape:SolidMolecular weight:483.52Depatuxizumab mafodotin
CAS:Depatuxizumab mafodotin, an antibody-drug conjugate (ADC) targeting the epidermal growth factor receptor (EGFR), is utilized in cancer research [1].Color and Shape:LiquidFN-1501
CAS:FN-1501 is a potent FLT3 and CDK inhibitor (IC50s: 2.47, 0.85, 1.96, and 0.28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3, respectively).Formula:C22H25N9OPurity:97.4%Color and Shape:SolidMolecular weight:431.49Ref: TM-T15335
1mg87.00€5mg177.00€10mg295.00€25mg537.00€50mg807.00€100mg1,099.00€1mL*10mM (DMSO)203.00€JAK-IN-28
CAS:JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of cancer and inflammatory diseases [1].Formula:C20H18ClN7OPurity:98%Color and Shape:SolidMolecular weight:407.86Limertinib
CAS:Limertinib (ASK120067) is a EGFR tyrosine kinase inhibitor targeting EGFR T790M, applicable for the study of non-small cell lung cancer.Formula:C29H32ClN7O2Purity:97.44%Color and Shape:SolidMolecular weight:546.06Ref: TM-T35897
1mg60.00€5mg130.00€10mg187.00€25mg341.00€50mg512.00€100mg770.00€200mg1,035.00€1mL*10mM (DMSO)156.00€EML4-ALK kinase inhibitor 1
CAS:Potent oral EML4-ALK inhibitor with a 1 nM IC50.Formula:C31H48N8O3Purity:99.62%Color and Shape:SolidMolecular weight:580.76Ref: TM-T11184
1mg92.00€5mg200.00€10mg299.00€25mg484.00€50mg658.00€100mg892.00€500mg1,773.00€1mL*10mM (DMSO)256.00€BCR-ABL-IN-1
CAS:BCR-ABL-IN-1 is a BCR-ABL tyrosine kinase inhibitor (pIC50: 6.46) and may be used in the research of chronic myelogenous leukemia.Formula:C23H21F4N5OPurity:98%Color and Shape:SolidMolecular weight:459.44Rogaratinib
CAS:Rogaratinib (BAY1163877) is an aberrant inhibitor of fibroblast growth factor receptor (FGFR).Formula:C23H26N6O3SPurity:99.54%Color and Shape:SolidMolecular weight:466.56FGFR2-IN-2
CAS:FGFR2-IN-2 is a specific FGFR2 inhibitor that inhibits FGFR1, FGFR2, and FGFR3, and can be used in the study of cancer and cardiovascular disease.Formula:C23H22N4OPurity:98.09%Color and Shape:SolidMolecular weight:370.45Tarlox-TKI
CAS:Tarlox-TKI (Kinase inhibitor-1) is a pan-ErbB inhibitor, the active ingredient of Tarloxotinib, which has antitumor activity.Formula:C19H18BrClN6OPurity:97.03%Color and Shape:SolidMolecular weight:461.74VEGFR-2-IN-6
CAS:VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].Formula:C20H21N7O2SPurity:99.01%Color and Shape:SolidMolecular weight:423.49JH-VIII-157-02
CAS:JH-VIII-157-02 inhibits ALK, specifically EML4-ALK variants, with IC50s of 2 nM.Formula:C28H27N5O2Purity:99.58%Color and Shape:SolidMolecular weight:465.55Ref: TM-T15612
1mg110.00€5mg227.00€10mg339.00€25mg530.00€50mg713.00€100mg982.00€1mL*10mM (DMSO)234.00€Fenlean
CAS:"Fenlean (FLZ) in phase I trial at Chinese Academy's Institute of Pharmacy for Parkinson's treatment."Formula:C26H27NO6Purity:98.99%Color and Shape:SolidMolecular weight:449.5Ref: TM-T31773
1mg73.00€2mg98.00€5mg165.00€10mg295.00€25mg532.00€50mg800.00€100mg954.00€200mg1,288.00€TP0427736 hydrochloride
CAS:TP0427736 hydrochloride is a novel and selective ALK5 inhibitor, capable of inhibiting Smad2/3 phosphorylation in A549 cells.Formula:C14H11ClN4S2Purity:98.99%Color and Shape:SolidMolecular weight:334.85PD 174265
CAS:PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.Formula:C17H15BrN4OPurity:99.51%Color and Shape:SolidMolecular weight:371.23AMPK-IN-3
CAS:AMPK-IN-3: potent, selective AMPK (α2/α1) & KDR inhibitor; IC50: 60.7/107/3820 nM; anticancer in K562 cells.Formula:C25H33N5O3Purity:97.25%Color and Shape:SolidMolecular weight:451.56A-935142
CAS:A-935142 enhances hERG (Kv 11.1) channels, slows inactivation, promotes activation, and shortens repolarization.Formula:C18H19F3N2O2Purity:98.97% - 99.91%Color and Shape:SolidMolecular weight:352.35EGFR-IN-11
CAS:EGFR-IN-11 selectively blocks EGFR-tyrosine kinase and promotes apoptosis; targets EGFRL858R/T790M/C797S, IC50=18 nM; halts cell cycle at G0/G1.Formula:C29H35N9O2SPurity:99.93%Color and Shape:SolidMolecular weight:573.71SKLB 1028
CAS:SKLB 1028, an oral EGFR/FLT3/Abl inhibitor, excels in AML and CML with Abl mutations.Formula:C24H29N9Purity:99.99% - >99.99%Color and Shape:SolidMolecular weight:443.55Ref: TM-T34656
1mg52.00€5mg113.00€10mg177.00€25mg358.00€50mg530.00€100mg758.00€500mg1,558.00€1mL*10mM (DMSO)126.00€Epitinib succinate
CAS:Epitinib succinate (HMPL-813 succinate) is an orally active and brain penetration EGFR tyrosine kinase inhibitor and can be used in studies about cancer.Formula:C28H32N6O6Purity:98.02% - 99.79%Color and Shape:SolidMolecular weight:548.59Ref: TM-T35914
1mg72.00€2mg92.00€5mg161.00€10mg258.00€25mg425.00€50mg583.00€100mg800.00€500mg1,603.00€EGFR-IN-99
CAS:EGFR-IN-99 (JBJ-03-142-02) is an EGFR and HER2 Exon 20 insertion mutation inhibitor for the study of non-small cell lung cancer (NSCLC).Formula:C25H22FN7O3Purity:97.75%Color and Shape:SolidMolecular weight:487.49CHMFL-EGFR-202
CAS:CHMFL-EGFR-202 is a potent, irreversible inhibitor of EGFR mutant kinase (IC50s: 5.3 nM and 8.3 nM for drug-resistant mutant EGFR T790M and WT EGFR kinases).Formula:C25H24ClN7O2Purity:99.66%Color and Shape:SolidMolecular weight:489.96Ref: TM-T10802
1mg109.00€2mg163.00€5mg241.00€10mg355.00€25mg532.00€50mg745.00€100mg1,018.00€1mL*10mM (DMSO)289.00€Tilfrinib
CAS:Tilfrinib is an effective and selective inhibitor of breast tumor kinase(Brk, IC50 = 3.15 nM) which displays anti-proliferative and anti-tumor activities.Formula:C17H13N3OPurity:99.54%Color and Shape:SolidMolecular weight:275.3Ref: TM-T17098
1mg43.00€2mg56.00€5mg93.00€10mg130.00€25mg243.00€50mg439.00€100mg645.00€500mg1,333.00€1mL*10mM (DMSO)93.00€VEGFR-3-IN-1
CAS:VEGFR-3-IN-1, a potent VEGFR3 inhibitor (IC50=110.4 nM), hinders tumor growth and VEGFR3 signaling, affecting HDLEC and MDA-MB cell proliferation/migration.Formula:C29H29ClF3N7OSPurity:99.95%Color and Shape:SolidMolecular weight:616.1EMI1
CAS:EMI1 targets mutated EGFR in drug-resistant NSCLC research.Formula:C20H18N2O3Purity:99.96%Color and Shape:SolidMolecular weight:334.37Vamotinib
CAS:Vamotinib (PF-114) is a tyrosine kinase inhibitor with antiproliferative and antitumor activity.Vamotinib is used in the study of Alzheimer's disease.Formula:C29H27F3N6OPurity:99.64%Color and Shape:SolidMolecular weight:532.56Ref: TM-T63746
1mg101.00€5mg245.00€10mg401.00€25mg717.00€50mg982.00€100mg1,341.00€200mg1,783.00€1mL*10mM (DMSO)288.00€Tafetinib
CAS:Tafetinib (SIM-010603) is a novel potent and orally available tyrosine kinase inhibitor with anti-angiogenic and anti-tumour activity.Formula:C24H29FN4O2Purity:96.23%Color and Shape:SolidMolecular weight:424.51BMS-605541
CAS:BMS-605541 is a potent and selective inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2) kinase activity(Ki=49 nM).
Formula:C19H17F2N5OSPurity:98.07%Color and Shape:SolidMolecular weight:401.43Cloperastine fendizoate
CAS:Cloperastine fendizoate (Hustazol) inhibits the hERG K+ currents in a concentration-dependent manner (IC50: 27 nM).Formula:C40H38ClNO5Purity:99.97%Color and Shape:SolidMolecular weight:648.19A 419259 trihydrochloride
CAS:A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).Formula:C29H37Cl3N6OPurity:99.75% - 99.96%Color and Shape:SolidMolecular weight:592STS-E412
CAS:STS-E412 is a tissue-protective and selective EPOR/CD131 receptor activator for the study of neurological disorders.Formula:C15H15ClN4O2Purity:99.01%Color and Shape:SolidMolecular weight:318.76BRD7389
CAS:BRD7389 is an inhibitor of RSK family kinase with IC50s of 1.5 μM, 2.4 μM, and 1.2 μM for RSK1, RSK2, and RSK3, respectively.Formula:C24H18N2O2Purity:99.51%Color and Shape:SolidMolecular weight:366.41Pimicotinib
CAS:Pimicotinib (ABSK021) is a potent CSF1R inhibitor with antitumor activity and can be used to study advanced solid tumors.Formula:C22H24N6O3Purity:99.8%Color and Shape:SolidMolecular weight:420.46Ref: TM-T79157
1mg52.00€5mg111.00€10mg170.00€25mg329.00€50mg528.00€100mg843.00€1mL*10mM (DMSO)156.00€JAK-STAT-IN-1
CAS:JAK-STAT-IN-1 is a specific JAK-STAT inhibitor indicated for the study of autoimmune diseases.Formula:C21H21N5O2Purity:99.59%Color and Shape:SolidMolecular weight:375.42PPY A
CAS:PPY A is a potent inhibitor of T315l mutant and wild-type Abl kinase and inhibits the growth of Bcr-Abl T315l mutant or wild-type Bcr-Abl gene-transformed cellsFormula:C22H20N4O2Purity:98.77%Color and Shape:SolidMolecular weight:372.42SU16f
CAS:SU16f, a 3-substituted indolin-2-one, is a selective PDGFRβ inhibitor; IC50: 10 nM (PDGFRβ), 140 nM (PDGFR1), 2.29 μM (PDGFR2), halts GC cell growth.Formula:C24H22N2O3Purity:97.69%Color and Shape:SolidMolecular weight:386.44Rezivertinib
CAS:Rezivertinib (BPI-7711) is an EGFR inhibitor with antitumor activity and can be used to study central nervous system diseases.Formula:C27H30N6O3Purity:99.26% - 99.98%Color and Shape:SolidMolecular weight:486.57Ref: TM-T36644
1mg60.00€5mg130.00€10mg177.00€25mg326.00€50mg467.00€100mg670.00€200mg888.00€1mL*10mM (DMSO)42.00€GTP-14564
CAS:GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3.Formula:C15H10N2OPurity:99.81%Color and Shape:SolidMolecular weight:234.25CTA 056
CAS:CTA 056 is an ITK inhibitor that inhibits the growth of MOLT-4 xenograft tumors in mice and can be used to study autoimmune disorders.Formula:C35H34N6OPurity:97.22% - 97.76%Color and Shape:SolidMolecular weight:554.68(R)-Zanubrutinib
CAS:(R)-Zanubrutinib ((R)-BGB-3111) is a selective inhibitor of Bruton tyrosine kinase (BTK).Formula:C27H29N5O3Purity:99.55%Color and Shape:SolidMolecular weight:471.55Ref: TM-T13447
1mg37.00€5mg80.00€10mg133.00€25mg215.00€50mg323.00€100mg442.00€200mg615.00€1mL*10mM (DMSO)85.00€LY 456236 hydrochloride
CAS:LY 456236 hydrochloride (MPMQ hydrochloride) is an mGlu1 receptor antagonist with an ic50 value of 143 nM.Formula:C16H16ClN3O2Purity:99.95%Color and Shape:SolidMolecular weight:317.77TG-89
CAS:TG-89 is an inhibitor of JAK2, JAK3, RET and FLT3, and has an IC50 value of 11.2 μM against JAK2, showing anticancer activity in the treatment of ovarian andFormula:C26H34N6O3SPurity:98.68%Color and Shape:SolidMolecular weight:510.65ARN25068
CAS:ARN25068 inhibits GSK-3β, FYN, DYRK1A kinases; acts in sub-micromolar range; combats tau hyperphosphorylation.Formula:C19H18N6SPurity:99.75%Color and Shape:SolidMolecular weight:362.45Conteltinib
CAS:Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK and Pyk2. It can be used to study lymphoma.Formula:C32H45N9O3SPurity:98.12% - 99.54%Color and Shape:SolidMolecular weight:635.82Ref: TM-T14997
1mg70.00€5mg150.00€10mg216.00€25mg369.00€50mg517.00€100mg722.00€1mL*10mM (DMSO)205.00€JNJ-49095397
CAS:JNJ-49095397 (RV568) is a p38 MAPK-α and p38 MAPK-γ kinase inhibitor for the study of respiratory syncytial virus infection.Formula:C34H36N6O4Purity:98.33% - 99.04%Color and Shape:SolidMolecular weight:592.69Dasatinib hydrochloride
CAS:Dasatinib hydrochloride is an oral Src/Bcr-Abl inhibitor with potent antitumor effects, Ki values of 16 pM (Src) and 30 pM (Bcr-Abl).Formula:C22H27Cl2N7O2SPurity:99.88% - 99.98%Color and Shape:SolidMolecular weight:524.47NX-2127
CAS:NX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S in cells.NX-2127 has potent antiproliferativeFormula:C39H45N9O5Purity:99.07%Color and Shape:SolidMolecular weight:719.83PP58
CAS:PP58 is an inhibitor of PDGFR, FGFR and Src family.Formula:C22H19Cl2N5O2Purity:99.21%Color and Shape:SolidMolecular weight:456.32SI-2 hydrochloride
CAS:SI-2 hydrochloride, an SRC-3 inhibitor, induces breast cancer cell death (IC50: 3-20 nM) with good oral bioavailability.Formula:C15H16ClN5Purity:98.6%Color and Shape:SolidMolecular weight:301.77Butyzamide
CAS:Butyzamide: oral Mpl activator, non-peptide, antagonizes TPO receptors, boosts hMpl, Ba/F3 cells, and enhances platelets in mice.Formula:C29H32Cl2N2O5SPurity:99.39% - 99.83%Color and Shape:SoildMolecular weight:591.55Ref: TM-T67894
1mg149.00€5mg253.00€10mg371.00€25mg573.00€50mg862.00€100mg1,305.00€200mg1,755.00€1mL*10mM (DMSO)329.00€SRX3207
CAS:SRX3207 is an inhibitor of Syk and PI3K and relieves tumor immunosuppression.Formula:C29H29N7O3SPurity:99.85%Color and Shape:SolidMolecular weight:555.65Sunvozertinib
CAS:Sunvozertinib (DZD9008) is a potent ErbBs and BTK inhibitor, with inhibitory effects on EGFR, Her2.Cost-effective and quality-assured.Formula:C29H35ClFN7O3Purity:98.11% - 99.63%Color and Shape:SolidMolecular weight:584.08Ref: TM-T64124
1mg34.00€5mg60.00€10mg85.00€25mg124.00€50mg200.00€100mg353.00€500mg1,314.00€1mL*10mM (DMSO)150.00€Izencitinib
CAS:Izencitinib (JNJ-8398) is a JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.Formula:C22H26N8Purity:99.82%Color and Shape:SolidMolecular weight:402.50Ref: TM-T35898
1mg84.00€5mg177.00€10mg281.00€25mg567.00€50mg888.00€100mg1,431.00€200mg1,963.00€1mL*10mM (DMSO)195.00€WDR5-0102
CAS:WDR5-0102 inhibits WDR5-MLL1 (Kd=4 μM), blocks MLL1 HMT activity, but doesn't affect SETD7 and 6 other HMTs.
Formula:C18H19ClN4O3Purity:98.03%Color and Shape:SolidMolecular weight:374.82H-9 dihydrochloride
CAS:H-9 dihydrochloride: Strong PKA inhibitor, curbs 5-HT response and EGF signaling, affects pharyngeal function.Formula:C11H15Cl2N3O2SPurity:97.3%Color and Shape:SolidMolecular weight:324.23Larotinib
CAS:Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 of 0.6 nM for EGFR.Formula:C24H26ClFN4O4Purity:99.73%Color and Shape:SolidMolecular weight:488.94MBM-55
CAS:MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM.Formula:C28H27FN6O2Purity:99.83%Color and Shape:SolidMolecular weight:498.55Ref: TM-T11960
1mg168.00€5mg281.00€10mg409.00€25mg627.00€50mg822.00€100mg1,108.00€500mg2,242.00€1mL*10mM (DMSO)309.00€HIF-2α-IN-3
CAS:HIF-2α-IN-3 is an allosteric inhibitor of HIF-2α (IC50: 0.4 μM; KD: 1.1 μM) with anticancer activity.Formula:C12H6ClN5O5Purity:98.11%Color and Shape:SolidMolecular weight:335.66Ref: TM-T11562
1mg73.00€2mg92.00€5mg161.00€10mg245.00€25mg480.00€50mg735.00€100mg999.00€200mg1,333.00€1mL*10mM (DMSO)172.00€c-Fms-IN-3
CAS:c-Fms-IN-3 is a novel inhibitor of the c-FMS and can be used in studies about antirheumatic and anti-inflammatory diseases.Formula:C23H30N6OPurity:99.87%Color and Shape:SolidMolecular weight:406.52Ref: TM-T10649
1mg52.00€5mg105.00€10mg161.00€25mg264.00€50mg358.00€100mg522.00€1mL*10mM (DMSO)110.00€Defactinib hydrochloride
CAS:Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK.Formula:C20H22ClF3N8O3SPurity:98.06% - 98.78%Color and Shape:SolidMolecular weight:546.95(Z)-FeCP-oxindole
CAS:(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.Formula:C19H15FeNOPurity:99.63% - 99.84%Color and Shape:SolidMolecular weight:329.17TC-S 7009
CAS:TC-S 7009: Strong HIF-2α inhibitor (Kd 81 nM), weak for HIF-1α; disrupts dimerization & gene expression.Formula:C12H6ClFN4O3Purity:99.46% - 99.71%Color and Shape:SolidMolecular weight:308.65(E)-FeCP-oxindole
CAS:(E)-FeCP-oxindole 是一种 VEGFR2 抑制剂，IC50 为 214 nM。Formula:C19H15FeNOPurity:99.85%Color and Shape:SolidMolecular weight:329.17Pz-1
CAS:Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks the blood supply required for RET-stimulated growth.Formula:C26H26N6O2Purity:99.89%Color and Shape:SolidMolecular weight:454.52(±)-Zanubrutinib
CAS:(±)-Zanubrutinib ((±)-BGB-3111) is a potent and orally available Bruton's tyrosine kinase (Btk) inhibitor that demonstrates superior oral bioavailability,Formula:C27H29N5O3Purity:99.09%Color and Shape:SolidMolecular weight:471.55Ref: TM-TQ0039
1mg47.00€5mg92.00€10mg145.00€25mg256.00€50mg409.00€100mg587.00€500mg1,215.00€1mL*10mM (DMSO)101.00€P505-15 Acetate
CAS:P505-15 Acetate inhibits spleen tyrosine kinase, reduces immune response and inflammation, and lowers arthritis severity.
Formula:C21H27N9O3Purity:99.99%Color and Shape:SolidMolecular weight:453.5Falnidamol
CAS:Falnidamol (BIBX 1382), an oral selective EGFR inhibitor, IC50 3 nM, weak on ErbB2 and others, anti-cancer pyrimido-pyrimidine.Formula:C18H19ClFN7Purity:98.816%Color and Shape:SolidMolecular weight:387.84Ref: TM-TQ0271
2mg39.00€5mg60.00€10mg96.00€25mg182.00€50mg318.00€100mg439.00€200mg612.00€1mL*10mM (DMSO)60.00€EGFR-IN-9
CAS:EGFR-IN-9 is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M).Formula:C29H24N4O3Purity:99.8%Color and Shape:SolidMolecular weight:476.53MY10
CAS:MY10, a potent and orally active inhibitor of the receptor protein tyrosine phosphatase (RPTPβ/ζ), effectively reduces binge-like ethanol consumption andFormula:C15H10F6OS2Purity:98.64%Color and Shape:SolidMolecular weight:384.36Ref: TM-T61678
1mg58.00€5mg126.00€10mg197.00€25mg394.00€50mg628.00€100mg982.00€200mg1,314.00€1mL*10mM (DMSO)167.00€
