Angiogenesis
Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.
Subcategories of "Angiogenesis"
- BTK(145 products)
- Bcr-Abl(102 products)
- EGFR(572 products)
- FAK(72 products)
- FLT(92 products)
- Fibroblast Growth Factor Receptor (FGFR)(170 products)
- JAK(245 products)
- PDGFR(126 products)
- RAAS(86 products)
- Src(78 products)
- Syk(38 products)
- Thrombin(47 products)
- VDA(2 products)
- VEGFR(268 products)
Show 6 more subcategories
Found 1414 products of "Angiogenesis"
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JAK1/TYK2-IN-1
CAS:<p>JAK1/TYK2-IN-1 is a dual inhibitor of TYK2 and JAK1 ( IC 50 = 29 and 41 nM respectively).</p>Formula:C18H20F3N7OColor and Shape:SolidMolecular weight:407.401M4K2234
CAS:<p>M4K2234 (26b) inhibits ALK2/ALK5 (IC50: 5/2144 nM), used as a probe for ALK1/2 kinases in cancer research.</p>Formula:C27H31FN4O2Color and Shape:SolidMolecular weight:462.56FLT3-IN-20
<p>FLT3-IN-20 (compound 34f) is a potent FLT3 inhibitor, demonstrating IC50 values of 1 nM for FLT3-D835Y and 4 nM for FLT3-ITD.</p>Formula:C28H33N7O2SColor and Shape:SolidMolecular weight:531.67HER2/neu (654-662) GP2
CAS:<p>Phage display selected Affibody ligands for HER2/neu from a protein library based on a 58-residue Staphylococcal protein A Z domain.</p>Formula:C42H77N9O11Purity:98%Color and Shape:SolidMolecular weight:884.11(R)-3-Hydroxy Midostaurin
CAS:<p>(R)-3-Hydroxy Midostaurin: potent kinase inhibitor, major midostaurin metabolite via CYP3A4, potential AML treatment.</p>Formula:C35H30N4O5Purity:98%Color and Shape:SolidMolecular weight:586.648VEGFR-2-IN-36
<p>VEGFR-2-IN-36 (compound 15) serves as a potent VEGFR-2 inhibitor, exhibiting an IC50 value of 0.067 μM, and acts as an apoptosis inducer with demonstrated</p>Formula:C24H23N7O5Purity:98%Color and Shape:SolidMolecular weight:489.48PROTAC FLT-3 degrader 1
CAS:<p>PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD)(IC50 0.6 nM),with anti-proliferative activity.</p>Formula:C52H61N9O9S2Purity:98%Color and Shape:SolidMolecular weight:1020.23Efimosfermin alfa
<p>Efimosfermin alfa is a humanized antibody targeting FGFR1.</p>Color and Shape:Odour LiquidAST5902 (trimesylate)
CAS:<p>AST5902 trimesylate is the primary metabolite of Alflutinib (AST2818) both in vivo and in vitro. It exhibits antitumor activity. Alflutinib functions as an EGFR inhibitor.</p>Formula:C30H41F3N8O11S3Color and Shape:SolidMolecular weight:842.884Anticancer agent 133
<p>Compound Rh2 (Anticancer agent 133) is a cytotoxic and antimetastatic agent that induces cell cycle arrest, apoptosis, and autophagy.</p>Formula:C24H19Cl3N5ORhPurity:98%Color and Shape:SolidMolecular weight:602.71EGFR-IN-22
CAS:<p>EGFR-IN-22: potent for EGFR (IC50: 4.91 nM) & L858R/T790M/C797S mutation (IC50: 0.54 nM).</p>Formula:C38H47BrFN10O2PColor and Shape:SolidMolecular weight:805.72AT-533
CAS:<p>AT-533 inhibits Hsp90, HSV, hinders HIF-1α/VEGF/VEGFR-2, Erk1/2, FAK, Akt/mTOR/p70S6K, and blocks tumor growth, angiogenesis, and HUVEC activities.</p>Formula:C23H30N4O3Purity:99.67%Color and Shape:SoildMolecular weight:410.51Angiogenesis related Compound Library
<p>A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high</p>Color and Shape:Odour SolidDisitamab vedotin
CAS:<p>Disitamab vedotin (RC-48) is a HER2-targeting ADC with MMAE, effective in HER2-expressing gastric cancer.</p>Purity:95.00% - 98%Color and Shape:LiquidMolecular weight:Approximately 144.15 kDaNRX-0492
CAS:<p>NRX-0492: orally active BTK degrader, induces ubiquitylation/proteasomal breakdown, potent with DC50 ≤0.2 nM, DC90 ≤0.5 nM, disrupts BCR signaling.</p>Formula:C43H51N11O6Color and Shape:SolidMolecular weight:817.94SIAIS100
<p>SIAIS100, a potent BCR-ABL PROTAC degrader, demonstrates a DC50 value of 2.7 nM, highlighting its efficacy.</p>Formula:C44H50ClF2N9O5SColor and Shape:SolidMolecular weight:890.44SNIPER(ABL)-050
<p>SNIPER(ABL)-050 is a chemical compound that combines Imatinib, an ABL inhibitor, with MV-1, an IAP ligand, using a linker.</p>Formula:C68H84N12O9Purity:98%Color and Shape:SolidMolecular weight:1213.47Sozinibercept
CAS:<p>Sozinibercept (OPT 302; VGX-300), a VEGFR-3 inhibitor, blocks VEGF-C/D to curb angiogenesis and vascular leakage, and treats rat diabetic retinal edema.</p>Color and Shape:LiquidMulti-target kinase inhibitor 2
<p>Compound 5K (Multi-target kinase inhibitor 2) is a multi-targeted kinase inhibitor demonstrating activity against EGFR, Her2, VEGFR2, and CDK2 with IC50 values</p>Purity:98%Color and Shape:Odour SolidCS-VIP 8
<p>CS-VIP 8 is a selective allosteric inhibitor of the WDR5 protein (Ki= 0.008 μM). It induces conformational changes in the MLL1 complex, causing the dissociation of MLL1 from the complex and inhibiting MLL1 histone methyltransferase activity, thereby regulating HOX gene expression. CS-VIP 8 shows potential for research in hematological diseases such as leukemia.</p>Formula:C43H52F4N12O7Color and Shape:SolidMolecular weight:924.4018
