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Angiogenesis

Angiogenesis

Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.

Subcategories of "Angiogenesis"

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Found 1414 products of "Angiogenesis"

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  • LDN-193189 Tetrahydrochloride

    CAS:
    <p>LDN193189 is a BMPI receptor inhibitor, blocking ALK2 and ALK3 effectively, while weak on ALK4, ALK5, ALK7.</p>
    Formula:C25H26Cl4N6
    Purity:98.21%
    Color and Shape:Solid
    Molecular weight:552.33
  • Bleximenib oxalate

    CAS:
    <p>Bleximenib oxalate (Menin-MLL inhibitor 24 oxalate) is a menin-MLL inhibitor that blocks the binding of the menin-KMT2A complex to chromatin at gene promoters.</p>
    Formula:C34H52FN7O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:689.82
  • Pentagamavunon-1

    CAS:
    <p>PGV-1, an oral Curcumin analog, induces apoptosis by inhibiting COX-2, VEGF, and NF-κB activation.</p>
    Formula:C23H24O3
    Color and Shape:Solid
    Molecular weight:348.43
  • Cediranib maleate

    CAS:
    <p>Cediranib maleate (AZD2171 maleate) is a VEGFR2 inhibitor that inhibits Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit.</p>
    Formula:C29H31FN4O7
    Color and Shape:Solid
    Molecular weight:566.58
  • N-piperidine Ibrutinib hydrochloride

    CAS:
    <p>N-piperidine Ibrutinib hydrochloride is a BTK inhibitor that inhibits WT BTK and C481S BTK , which inhibits the growth and proliferation of cancer cells.</p>
    Formula:C22H23ClN6O
    Purity:98.83%
    Color and Shape:Solid
    Molecular weight:422.91
  • Poseltinib

    CAS:
    <p>Poseltinib is an oral, irreversible BTK inhibitor (IC50 1.95 nM) with higher selectivity over BMX, TEC, and TXK, blocking BCR, FcR, and TLR signaling.</p>
    Formula:C26H26N6O3
    Color and Shape:Solid
    Molecular weight:470.52
  • EW-7195

    CAS:
    <p>EW-7195 inhibits ALK5/TGFβR1 (&gt;300x selective over p38α) with 4.83 nM IC50, blocking TGF-β1 signaling, EMT, and breast cancer lung metastasis.</p>
    Formula:C23H18N8
    Purity:98.76%
    Color and Shape:Solid
    Molecular weight:406.44
  • Imatinib D4

    CAS:
    <p>Imatinib D4 is a deuterium-labeled Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, PDGFR, v-Abl, and c-kit kinase activity.</p>
    Formula:C29H31N7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:497.63
  • Surfen dihydrochloride

    CAS:
    <p>Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a heparin sulfate antagonist with antimicrobial properties and inhibits blockade of signaling.</p>
    Formula:C21H22Cl2N6O
    Purity:97.08%
    Color and Shape:Solid
    Molecular weight:445.35
  • Gefitinib-d8

    CAS:
    <p>Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib D8 is a deuterium labeled Gefitinib.</p>
    Formula:C22H24ClFN4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:454.95
  • Ribociclib-d6

    CAS:
    <p>Ribociclib-d6 is a deuterated compound of Ribociclib (LEE011) for isotope tracing.Ribociclib is an orally available CDK4/6 inhibitor with antitumor activity.</p>
    Formula:C23H30N8O
    Color and Shape:Solid
    Molecular weight:440.57
  • Disitamab

    CAS:
    <p>Disitamab (RC48-0) is a humanized anti-HER2 monoclonal antibody used in ADC synthesis.</p>
    Purity:95.00%
    Color and Shape:Liquid
  • Aflibercept

    CAS:
    <p>Aflibercept has a wide range of applications in life science related research.</p>
    Color and Shape:Liquid
  • KG-548

    CAS:
    <p>KG-548 is a dual inhibitor of ARNT/TACC3 and HIF-1α, inhibiting lactate production, and can be used in cancer research.</p>
    Formula:C9H4F6N4
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:282.15
  • SM1-71

    CAS:
    <p>SM1-71 is a TAK1 inhibitor that inhibits MKNK2 and RSK2.SM1-71 acts as a kinase probe with anticancer activity.</p>
    Formula:C24H26ClN7O
    Purity:96%
    Color and Shape:Solid
    Molecular weight:463.96
  • Elsubrutinib

    CAS:
    <p>Elsubrutinib (ABBV-105) is a highly active, potent, and selective orally-administered inhibitor of Bruton's tyrosine kinase (BTK). It irreversibly inhibits the catalytic domain of BTK with an IC50 value of 0.18 μM. Elsubrutinib holds potential for the advancement of research on inflammatory diseases.</p>
    Formula:C17H19N3O2
    Color and Shape:Solid
    Molecular weight:297.358
  • Itacitinib adipate

    CAS:
    <p>Itacitinib adipate: oral JAK1 inhibitor, tested in phase II myelofibrosis trial.</p>
    Formula:C32H33F4N9O5
    Color and Shape:Solid
    Molecular weight:699.66
  • Conteltinib tetrahydrochloride


    <p>Conteltinibtetrahydrochloride (CT-707 tetrahydrochloride) is the tetrahydrochloride form of Conteltinib. It acts as an inhibitor for FAK (IC50=1.6 nM), ALK, and Pyk2. When used in combination with Cabozantinib, Conteltinib tetrahydrochloride exhibits a synergistic antitumor effect.</p>
    Formula:C32H49Cl4N9O3S
    Color and Shape:Solid
    Molecular weight:781.667
  • Afatinib D6

    CAS:
    <p>Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor.</p>
    Formula:C24H25ClFN5O3
    Color and Shape:Solid
    Molecular weight:491.98
  • Regorafenib-d3

    CAS:
    <p>Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase.</p>
    Formula:C21H15ClF4N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:485.83