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Angiogenesis

Angiogenesis

Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.

Subcategories of "Angiogenesis"

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Found 1522 products of "Angiogenesis"

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  • pan-HER-IN-1

    CAS:
    <p>Compound C5: Irreversible, oral pan-HER inhibitor with low IC50s for EGFR/HERs; induces apoptosis and has antitumor effects.</p>
    Formula:C19H14BrN5O
    Color and Shape:Solid
    Molecular weight:408.25
  • EGFR/HER2/TS-IN-2

    CAS:
    <p>EGFR/HER2/TS-IN-2: Strong EGFR, HER2 &amp; TS inhibitor; EGFR IC50=0.173μM, HER2 IC50=0.125μM, TS IC50=1.12μM; kills MDA-MB-231 cells (IC50=1.69μM).</p>
    Formula:C26H21N7OS2
    Color and Shape:Solid
    Molecular weight:511.62
  • BSc5371

    CAS:
    <p>BSc5371: Irreversible FLT3 inhibitor; Kds 0.83-5.8 nM for various FLT3 mutants including wild type.</p>
    Formula:C24H31N5O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:485.6
  • Nimotuzumab

    CAS:
    <p>Nimotuzumab is a humanized therapeutic monoclonal antibody against epidermal growth factor receptor EGFR).</p>
    Purity:95.00% - 98.5% (SDS-PAGE); 96.4% (SEC-HPLC)
    Color and Shape:Liquid
  • Esuberaprost Sodium

    CAS:
    <p>Famitinib (SHR1020), an oral drug, inhibits c-kit, VEGFR-2, and PDGFRβ (IC50: 2.3/4.7/6.6 nM) and triggers apoptosis in gastric cancer.</p>
    Formula:C23H27FN4O2
    Color and Shape:Solid
    Molecular weight:410.48
  • MS 154N

    CAS:
    <p>MS 154N is a negative control for MS 154, binds WT/L858R EGFR tightly (Kd 3-4.3nM), doesn't trigger mutant EGFR degradation.</p>
    Formula:C47H56ClFN8O8
    Color and Shape:Solid
    Molecular weight:915.45
  • c-ABL-IN-2

    CAS:
    <p>C-ABL-IN-2 is a potent c-Abl protein inhibitor, promising for research in cancer and neurodegenerative diseases like ALS and PD.</p>
    Formula:C21H20N4O
    Color and Shape:Solid
    Molecular weight:344.41
  • BPTQ

    CAS:
    <p>BPTQ: DNA intercalator, halts cancer cell growth by blocking S/G2/M phases.</p>
    Formula:C17H16N4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:308.4
  • JNJ-47117096 hydrochloride

    CAS:
    JNJ-47117096 hydrochloride is potent and selective MELK inhibitor, with an IC50 of 23 nM, also effectively inhibits Flt3, with an IC50 of 18 nM.
    Formula:C21H23ClN4O2
    Color and Shape:Solid
    Molecular weight:398.89
  • JAK-2/3-IN-2

    CAS:
    <p>JAK-2/3-IN-2 (Compound 3h) is a potent JAK2 &amp; JAK3 inhibitor with IC50s of 23.85 nM (JAK2) &amp; 18.9 nM (JAK3).</p>
    Formula:C19H19ClN2OS
    Color and Shape:Solid
    Molecular weight:358.89
  • MAX-40279 hemiadipate

    CAS:
    <p>MAX-40279 hemiadipate: Potent FLT3/FGFR inhibitor; potential in AML treatment. (Patent WO2021180032A1)</p>
    Formula:C50H56F2N12O6S2
    Color and Shape:Solid
    Molecular weight:1023.19
  • Squarunkin A hydrochloride

    CAS:
    <p>Squarunkin A HCl inhibits UNC119-cargo binding, specifically blocks Src kinase activation, IC50=10 nm.</p>
    Formula:C25H33ClF3N5O4
    Color and Shape:Soild
    Molecular weight:560.02
  • EGFR-IN-67

    CAS:
    <p>EGFR-IN-67 (Compound 7d) is a potent inhibitor of EGFR with anticancer activity (IC 50 = 0.34 μM) [1].</p>
    Formula:C18H17N3S
    Color and Shape:Solid
    Molecular weight:307.41
  • TK4g

    CAS:
    <p>TK4g, a potent JAK inhibitor, has IC50s of 12.61 nM (JAK2) &amp; 15.80 nM (JAK3); promising for lymphoid diseases &amp; leukemia research.</p>
    Formula:C19H19N3O4S
    Color and Shape:Solid
    Molecular weight:385.44
  • VEGFR-2/BRAF-IN-2


    <p>VEGFR-2/BRAF-IN-2 inhibits VEGFR-2, BRAF V600E, BRAF WT (IC50: 0.111/0.089/0.071 µM); induces G1 arrest and apoptosis.</p>
    Formula:C26H21ClF3N5O3S2
    Color and Shape:Solid
    Molecular weight:608.05
  • TC-S 7003

    CAS:
    TC-S 7003 (Lck Inhibitor) is a Lck inhibitor with anti-inflammatory activity that inhibits T-cell proliferation and can be used to study arthritis.
    Formula:C31H30N8O
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:530.62
  • EGFR-IN-68

    CAS:
    <p>EGFR-IN-68, an EGFR inhibitor, has an IC50 of 0.33 μM and shows significant anticancer effects.</p>
    Formula:C24H22N2O
    Color and Shape:Solid
    Molecular weight:354.44
  • (E/Z)-AG490

    CAS:
    <p>(E/Z)-AG490 is a racemic mix of (E)- and (Z)-isomers; it inhibits tyrosine kinase, EGFR, Stat-3, and JAK2/3.</p>
    Formula:C17H14N2O3
    Color and Shape:Solid
    Molecular weight:294.3
  • ULK1-IN-2

    CAS:
    <p>ULK1-IN-2, a potent anticancer agent, inhibits ULK1, induces apoptosis, blocks autophagy, and shows high cytotoxicity with an IC50 of 1.94 μM in A549 cells.</p>
    Formula:C19H16BrFN4O6
    Purity:99.25% - 99.25%
    Color and Shape:Solid
    Molecular weight:495.26
  • T338C Src-IN-2

    CAS:
    <p>T338C Src-IN-2: Potent c-Src T338C kinase inhibitor; IC50: 317 nM, T338C/V323A: 57 nM, T338C/V323S: 19 nM.</p>
    Formula:C17H18FN5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:327.36