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Angiogenesis

Angiogenesis

Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.

Subcategories of "Angiogenesis"

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Found 1430 products of "Angiogenesis"

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  • FLT3/ITD-IN-4

    CAS:
    <p>FLT3/ITD-IN-4 inhibits FLT3-ITD mutations in acute myeloid leukemia (IC50: 2.3 nM).</p>
    Formula:C25H22N4O5
    Color and Shape:Solid
    Molecular weight:458.47
  • EGFR-IN-30

    CAS:
    <p>EGFR-IN-30 is an EGFR inhibitor (IC50: 1-10 nM, &lt;1 nM WT/mutants) with potential in cancer research.</p>
    Formula:C28H33BrN7O2P
    Color and Shape:Solid
    Molecular weight:610.49
  • FGFR-IN-2

    CAS:
    <p>FGFR-IN-2 (compound 1) is a potent inhibitor of FGFR, acting on FGFR1 (IC50: 7.3 nM), FGFR2 (IC50: 4.3 nM), FGFR3 (IC50: 7.6 nM) and FGFR4 (IC50: 11 nM).</p>
    Formula:C25H30N6O2
    Color and Shape:Solid
    Molecular weight:446.54
  • EGFR kinase inhibitor 1

    CAS:
    <p>Potent EGFR blocker; acts on WT, L858R/T790M (IC50: 1.7 nM), less on T790M/C797S; stalls cell cycle, induces apoptosis, deters metastasis.</p>
    Formula:C30H31N7O2
    Color and Shape:Solid
    Molecular weight:521.61
  • Risvodetinib

    CAS:
    <p>Risvodetinib: potent inhibitor of protein tyrosine kinases c-Abl1, c-Abl2, and c-kit.</p>
    Formula:C33H34N8O2
    Color and Shape:Solid
    Molecular weight:574.68
  • Henatinib

    CAS:
    <p>Henatinib: orally active multi-kinase inhibitor targeting VEGFR-2, c-kit, PDGFR with antitumor effects.</p>
    Formula:C25H29FN4O4
    Color and Shape:Solid
    Molecular weight:468.52
  • 10Z-Hymenialdisine

    CAS:
    <p>Pan kinase inhibitor</p>
    Formula:C11H10BrN5O2
    Purity:98%
    Color and Shape:Light Yellow Solid
    Molecular weight:324.13
  • BPR1J-340

    CAS:
    <p>BPR1J-340, a novel potent FLT3 inhibitor, shows anticancer promise, with IC50 ~25 nM and GC50 ~5 nM, causing apoptosis in AML cells.</p>
    Formula:C29H34N8O3
    Color and Shape:Solid
    Molecular weight:542.63
  • TCJL37

    CAS:
    <p>TCJL37: potent, selective TYK2 inhibitor (K i 1.6 nM), oral, for IBD research.</p>
    Formula:C17H11ClF2N4O2
    Color and Shape:Solid
    Molecular weight:376.74
  • TAK-659

    CAS:
    <p>TAK-659 is a spleen tyrosine kinase (SYK) inhibitor.</p>
    Formula:C17H21FN6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:344.39
  • MTP

    CAS:
    <p>MTP, a PKM2 inhibitor, promotes apoptosis in cancer cells via caspase-3 activation while also inducing autophagy and enhancing ROS generation.</p>
    Formula:C29H23F3N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:516.51
  • BTK-IN-11

    CAS:
    <p>BTK-IN-11: potent BTK inhibitor; may research autoimmune, inflammatory diseases, cancer. (Patent WO2022063101A1, Z2)</p>
    Formula:C26H22ClN5O3
    Color and Shape:Solid
    Molecular weight:487.94
  • SD 1008

    CAS:
    <p>SD 1008 is a JAK2/STAT3 signaling pathway inhibitor. SD 1008 inhibits activation of STAT3, JAK2, and Src.</p>
    Formula:C18H19NO5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:329.35
  • SNIPER(TACC3)-11

    CAS:
    <p>SNIPER(TACC3)-11 is a powerful FGFR3-TACC3 protein degrader, reducing its amount and hindering FGFR3-TACC3+ cancer cell growth.</p>
    Formula:C51H66N10O7S2
    Color and Shape:Solid
    Molecular weight:995.26
  • JAK-IN-24

    CAS:
    <p>JAK-IN-24: JAK inhibitor, IC50: 0.534 nM (4 μM ATP), 24 nM (1mM ATP), STAT5 phosphorylation IC50: 86.171 nM.</p>
    Formula:C20H25N5O2
    Color and Shape:Solid
    Molecular weight:367.44
  • JAK-IN-17


    <p>"JAK-IN-17: Potent JAK inhibitor for studying ocular, skin, and respiratory diseases."</p>
    Formula:C33H38F2N6O8
    Color and Shape:Solid
    Molecular weight:684.69
  • BTK-IN-17


    <p>BTK-IN-17: selective, oral BTK inhibitor, IC50=13.7 nM, reduces p-BTK Y223/p-PLCγ2 Y1217, anti-inflammatory.</p>
    Formula:C26H23N7O2
    Color and Shape:Solid
    Molecular weight:465.51
  • FLT3-IN-14

    CAS:
    <p>FLT3-IN-14: FLT3 inhibitor; FLT3-WT IC50=5.6nM, FLT3-ITD IC50=1.4nM; blocks Y591 phosphorylation; G1 arrest; pro-apoptotic.</p>
    Formula:C25H24N6O2S
    Color and Shape:Solid
    Molecular weight:472.56
  • ALK/EGFR-IN-1

    CAS:
    <p>ALK/EGFR-IN-1 (Compound 8l) is a dual inhibitor targeting both ALK and EGFR, effectively blocking their phosphorylation.</p>
    Formula:C27H34ClN7O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:572.12
  • BTK-IN-18

    CAS:
    <p>BTK-IN-18 is a potent, reversible inhibitor of Bruton's tyrosine kinase (BTK) with an inhibitory concentration (IC50) of 0.002 µM.</p>
    Formula:C20H22Cl2N6O
    Color and Shape:Solid
    Molecular weight:433.33