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Angiogenesis

Angiogenesis

Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.

Subcategories of "Angiogenesis"

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Found 2121 products of "Angiogenesis"

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  • HER2-IN-8
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    HER2-IN-8

    CAS:
    HER2-IN-8 is an inhibitor of HER-2 that can be used in the study of cancer and inflammation-related diseases.
    Formula:C26H25F2N9O3
    Color and Shape:Solid
    Molecular weight:549.53

    Ref: TM-T63881

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    EGFR/HER2-IN-8

    EGFR/HER2-IN-8 inhibits EGFR, HER2, DHFR (IC50: 0.45, 0.244, 5.669 μM); useful in cancer research, safe and selective.
    Formula:C16H16N4O2S
    Color and Shape:Solid
    Molecular weight:328.39

    Ref: TM-T60938

  • OXA-11
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    OXA-11

    CAS:
    OXA-11 (FAK-IN-16) is a FAK inhibitor with anti-tumor activity, useful for cancer research.
    Formula:C37H49F3N7O5P
    Purity:98.70% - 99.20%
    Color and Shape:Solid
    Molecular weight:759.8

    Ref: TM-T28277

  • CGP062464
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    CGP062464

    CAS:
    CGP062464 is an inhibitor of the tyrosine kinase c-Src, with an IC50 of less than 50 nM. It is utilized in research related to osteoporosis and tumor-induced hypercalcemia.
    Formula:C18H14N4
    Color and Shape:Solid
    Molecular weight:286.331

    Ref: TM-T205732

  • DDO-02267
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    DDO-02267

    CAS:
    <p>DDO-02267 is a selective lysine-targeted covalent inhibitor of ALKBH5, with an IC50 value of 0.49 μM. It increases levels of N6-methyladenosine (m6A) and targets the ALKBH5-AXL signaling axis. DDO-02267 serves as a probe for studying the biological function of mRNA demethylases.</p>
    Formula:C18H12N2O7S
    Color and Shape:Solid
    Molecular weight:400.362

    Ref: TM-T204967

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    FLT3/TrKA-IN-1

    FLT3/TrKA-IN-1: Potent dual kinase inhibitor for FLT3 & TrKA, promising for AML research.
    Formula:C28H30N4O2
    Color and Shape:Solid
    Molecular weight:454.56

    Ref: TM-T62801

  • Multi-kinase-IN-1
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    Multi-kinase-IN-1

    CAS:
    Multi-kinase-IN-1, a powerful kinase inhibitor, exhibits antitumor properties by inducing cell apoptosis.
    Formula:C35H36F2N6O6S
    Color and Shape:Solid
    Molecular weight:706.76

    Ref: TM-T72604

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    BTK-IN-32

    CAS:
    BTK-IN-32 (compound C2) acts as a potent BTK inhibitor. Unlike isolated kinase domains, this compound activates full-length BTK as well as its smaller multidomain fragments [1].
    Formula:C35H35ClN4O3S
    Molecular weight:627.2

    Ref: TM-T85925

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    EGFR-IN-45

    EGFR-IN-45: Strong EGFR/CDK2 inhibitor (IC50s: 0.4 & 1.6 μM), halts cancer cell cycle pre-G1, prompts apoptosis, also targets Topo I/II.
    Formula:C28H23N7O
    Color and Shape:Solid
    Molecular weight:473.53

    Ref: TM-T63070

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    VEGFR-2-IN-12

    VEGFR-2-IN-12 (compound 6g), a 2-oxoquinoxalinyl-1,2,4-triazole, is a potent inhibitor of VEGFR-2 (IC50: 0.037 μM). VEGFR-2-IN-12 has anti-tumour effects.
    Formula:C22H24N6O3S
    Color and Shape:Solid
    Molecular weight:452.53

    Ref: TM-T62763

  • Neptinib
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    Neptinib

    CAS:
    Neptinib (NEP010), a derivative of Afatinib, exhibits enhanced antitumor properties and improved pharmacokinetics when administered orally. It demonstrates a notable suppression of tumor expansion in mouse models of non-small cell lung cancer harboring various EGFR mutations. Furthermore, Neptinib effectively inhibits the EGFR kinase family, exhibiting IC 50 values of 0.24 nM for EGFR wt, 7.25 nM for EGFR L858R/T790M, 0.46 nM for EGFR L858R, and 1.79 nM for EGFR T790M.
    Formula:C22H23ClFN5O2
    Color and Shape:Solid
    Molecular weight:443.90

    Ref: TM-T89923

  • Protein kinase inhibitor 13
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    Protein kinase inhibitor 13

    CAS:
    Protein kinase inhibitor 13 (Compound I-90) functions as a kinase inhibitor, specifically targeting kinases such as PIM-1, CDK-2, GSK-3, and SRC.
    Formula:C19H20FN5OS
    Color and Shape:Solid
    Molecular weight:385.458

    Ref: TM-T205679

  • Tyk2-IN-14
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    Tyk2-IN-14

    CAS:
    Tyk2-IN-14, a small molecule inhibitor of TYK2, is significant in treating inflammatory diseases and conditions linked to hypersecretion of IFNa and interferons [1].
    Formula:C22H21N9O2
    Color and Shape:Solid
    Molecular weight:443.46

    Ref: TM-T87583

  • EGFR-IN-35
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    EGFR-IN-35

    CAS:
    EGFR-IN-35, an acrylamide-based EGFR inhibitor, shows promise for EGFR mutation-related cancers like NSCLC.
    Formula:C25H24ClN7O2
    Color and Shape:Solid
    Molecular weight:489.96

    Ref: TM-T63282

  • JAK3/BTK-IN-3
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    JAK3/BTK-IN-3

    CAS:
    JAK3/BTK-IN-3: strong dual JAK3/BTK suppressor, promising for autoimmune disease research.
    Formula:C22H28N8O
    Color and Shape:Solid
    Molecular weight:420.51

    Ref: TM-T62234

  • Paeoniflorin-6′-O-benzene sulfonate
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    Paeoniflorin-6′-O-benzene sulfonate

    CAS:
    Paeoniflorin-6′-O-benzene sulfonate (CP-25) acts as an inhibitor of G protein-coupled receptor kinase 2 (GRK2), preventing its translocation to the cell membrane and inhibiting the JAK1/STAT3 signaling pathway. It suppresses HaCaT cell proliferation induced by IL-17A/CXCL2. In mouse models, CP-25 reduces the levels of inflammatory cytokines and chemokines such as IL-17A, IL-17F, IFN-γ, TNF-α, IL-22, IL-23, CXCL2, CXCL3, and CXCL9, thereby alleviating psoriasis induced by Imiquimod.
    Formula:C29H32O13S
    Color and Shape:Solid
    Molecular weight:620.622

    Ref: TM-T206189

  • Tyk2-IN-3
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    Tyk2-IN-3

    CAS:
    Tyk2-IN-3 is an inhibitor of Tyk2 pseudokinase (IC50: 485 nM).
    Formula:C25H24N6O3S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:520.63

    Ref: TM-T13233

  • EGFR-IN-133
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    EGFR-IN-133

    CAS:
    EGFR-IN-133 (Compound 24) serves as an inhibitor targeting various mutations of the EGFR, including the wild type, L858R/T790M, d19/T790M, L858R/T790M/C797S, and d19/T790M/C797S with respective IC50 values of 0.1, 0.044, 0.036, 0.04, and 0.054 nM. The compound exhibits favorable pharmacokinetic properties and high oral bioavailability.
    Formula:C27H29F2N7O3
    Color and Shape:Solid
    Molecular weight:537.56

    Ref: TM-T201790

  • (-)-Cevimeline hydrochloride hemihydrate
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    (-)-Cevimeline hydrochloride hemihydrate

    (-)-Cevimeline HCl hemihydrate, a muscarinic agonist, treats Sjogren's xerostomia. Quick absorption, species-dependent metabolism.
    Formula:C10H19ClNO1·5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:244.78

    Ref: TM-T13421

  • FGFR-IN-5
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    FGFR-IN-5

    CAS:
    FGFR-IN-5 is a potent inhibitor of FGFR. FGFR-IN-5 has potential for research in cancer diseases.
    Formula:C25H22N6O3
    Color and Shape:Solid
    Molecular weight:454.48

    Ref: TM-T62794