Angiogenesis
Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.
Subcategories of "Angiogenesis"
- BTK(145 products)
- Bcr-Abl(102 products)
- EGFR(572 products)
- FAK(72 products)
- FLT(92 products)
- Fibroblast Growth Factor Receptor (FGFR)(170 products)
- JAK(245 products)
- PDGFR(126 products)
- RAAS(86 products)
- Src(78 products)
- Syk(38 products)
- Thrombin(47 products)
- VDA(2 products)
- VEGFR(268 products)
Show 6 more subcategories
Found 1414 products of "Angiogenesis"
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INCB-000928
CAS:<p>Zilurgisertib (INCB-000928) is a selective and potent ALK 2 inhibitor for the study of cancer and MF anemia.</p>Formula:C30H38N4O3Purity:98.93%Color and Shape:SolidMolecular weight:502.65Efruxifermin
CAS:<p>Efruxifermin, a modified FGF21 with IgG1 Fc, has increased stability and affinity. Used in non-alcoholic steatohepatitis research.</p>Color and Shape:LiquidMersalyl
CAS:<p>Mersalyl is an organic mercurial diuretic.</p>Formula:C13H16HgNNaO6Color and Shape:SolidMolecular weight:505.854Vulinacimab
CAS:<p>Vulinacimab (HLX-06) is a mAb targeting VEGFR-2, used in cancer research, vital for tumor angiogenesis and endothelial cell functions.</p>Color and Shape:LiquidALK-IN-9
CAS:<p>ALK-IN-9 effectively inhibits cell growth with IC50 <0.2 nM for Ba/F3-EML4-ALK, KM12, KG-1.</p>Formula:C20H21FN6O3Color and Shape:SolidMolecular weight:412.425Sunitinib-d10
CAS:<p>Sunitinib D10, a deuterium-enriched version, inhibits VEGFR2 and PDGFRβ tyrosine kinases (IC50: 80 nM/2 nM).</p>Formula:C22H27FN4O2Purity:98%Color and Shape:SolidMolecular weight:408.54Ilunocitinib
CAS:<p>Ilunocitinib is a non-selective and orally active Janus kinase (JAK) inhibitor for pruritus and atopic dermatitis caused by atopic dermatitis in dogs.</p>Formula:C17H17N7O2SPurity:99.88%Color and Shape:SolidMolecular weight:383.43Tirbanibulin dihydrochloride
CAS:<p>Tirbanibulin is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).</p>Formula:C26H31Cl2N3O3Purity:98%Color and Shape:SolidMolecular weight:504.45Tetrac
CAS:<p>Tetrac (Tetraiodothyroacetic acid) is a derivative of L-thyroxine (T4), a thyroxine integrin receptor antagonist.Tetrac induces antiproliferation by blocking</p>Formula:C14H8I4O4Purity:99.04%Color and Shape:SolidMolecular weight:747.83(3S,4S)-PF-06459988
CAS:<p>(3S, 4S)-PF-06459988, a less active S enantiomer, specifically inhibits T790M mutant EGFR with high selectivity.</p>Formula:C19H22ClN7O3Color and Shape:SolidMolecular weight:431.88PND-1186 hydrochloride
CAS:<p>PND-1186 hydrochloride (VS-4718 hydrochloride) is a highly specific, reversible and potent inhibitor of FAK (IC50: 1.5 nM), which can selectively induce</p>Formula:C25H27ClF3N5O3Color and Shape:SolidMolecular weight:537.97Naphazoline nitrate
CAS:<p>Naphazoline nitrate: α1-adrenergic agonist, induces autophagy, necrosis in cancer cells, inhibits differentiation, treats congestion and eye issues.</p>Formula:C14H15N3O3Purity:98%Color and Shape:White Crystalline Powder White SolidMolecular weight:273.29FLT3-IN-16
CAS:<p>FLT3-IN-16 is a potent FLT3 inhibitor (IC50 = 1.1 μM) for acute myeloid leukemia research.</p>Formula:C15H15N3O2SPurity:99.21%Color and Shape:SolidMolecular weight:301.36iHCK-37
CAS:<p>iHCK-37 (ASN05260065) is an Hck inhibitor with antitumor activity and blocks HIV-1 replication, used in chronic myelogenous leukemia (CML) research.</p>Formula:C30H32N4O2S2Purity:99.97%Color and Shape:SolidMolecular weight:544.73Asciminib hydrochloride
CAS:<p>Asciminib (ABL001) hydrochloride is a selective and potent mutant BCR-ABL1 inhibitor that inhibits Ba/F3 cell growth (IC50: 0.25 nM).</p>Formula:C20H19Cl2F2N5O3Color and Shape:SolidMolecular weight:486.3Nilotinib-d6
CAS:<p>Nilotinib D6 is a deuterium labeled Nilotinib which is an orally available inhibitor of Bcr-Abl tyrosine kinase ,and with antineoplastic activity.</p>Formula:C28H22F3N7OPurity:98%Color and Shape:SolidMolecular weight:535.55Telatinib mesylate
CAS:<p>Telatinib mesylate is a potent, orally active inhibitor of VEGFR2 (IC50: 6 nM), VEGFR3 (IC50: 4 nM), PDGFα (IC50: 15 nM) and c-Kit (IC50: 1 nM).</p>Formula:C21H20ClN5O6SColor and Shape:SolidMolecular weight:505.93BI-4142
CAS:<p>BI-4142 is a HER2 inhibitor that inhibits cancer cell proliferation, suppresses her2-dependent cell lines and inhibits downstream signalling.</p>Formula:C28H27N9O2Purity:97.21% - 98.09%Color and Shape:SolidMolecular weight:521.57IBT6A hydrochloride
CAS:<p>IBT6A hydrochloride: Ibrutinib impurity, Btk inhibitor IC50: 0.5 nM, used in dimer/adduct synthesis.</p>Formula:C22H23ClN6OColor and Shape:SolidMolecular weight:422.91Erlotinib-d6 hydrochloride
CAS:<p>Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib D6 hydrochloride a deuterium labeled Erlotinib Hydrochloride.</p>Formula:C22H24ClN3O4Purity:98%Color and Shape:SolidMolecular weight:435.93Rociletinib hydrobromide
CAS:<p>Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).</p>Formula:C27H29BrF3N7O3Purity:98%Color and Shape:SolidMolecular weight:636.46(Z)-Orantinib
CAS:<p>(Z)-Orantinib, oral ATP-competitive blocker for Flk-1/KDR, PDGFRβ, FGFR1 (IC50: 2.1, 0.008, 1.2 μM), is a strong antiangiogenic, antitumor drug.</p>Formula:C18H18N2O3Color and Shape:SolidMolecular weight:310.35Ponatinib-d8
CAS:<p>Ponatinib D8 is a deuterium-enriched, oral multi-kinase inhibitor (Abl, PDGFRα, VEGFR2, FGFR1, Src; IC50s: 0.37-5.4 nM).</p>Formula:C29H27F3N6OPurity:98%Color and Shape:SolidMolecular weight:540.61SU11652
CAS:<p>SU11652 is an effective and competitive receptor tyrosine kinase (RTK) inhibitor, including VEGFR, FGFR, PDGFR, and Kit.</p>Formula:C22H27ClN4O2Purity:99.14%Color and Shape:SolidMolecular weight:414.93Tucatinib hemiethanolate
CAS:<p>Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.</p>Formula:C54H54N16O5Purity:99.76%Color and Shape:SolidMolecular weight:1007.11Iruplinalkib
CAS:<p>Iruplinalkib (WX-0593) is an orally active, selective and potent ALK and ROS1 tyrosine kinase inhibitor with anticancer activity for use in the study of non-small cell lung cancer.</p>Formula:C29H38ClN6O2PPurity:97.38%Color and Shape:SolidMolecular weight:569.08(E/Z)-Zotiraciclib hydrochloride
CAS:<p>(E/Z)-Zotiraciclib ((E/Z)-TG02) hydrochloride is a potent inhibitor of CDK2, JAK2, and FLT3.</p>Formula:C23H25ClN4OColor and Shape:SolidMolecular weight:408.93Atinvicitinib
CAS:<p>Atinvicitinib, a selective JAK1 inhibitor, blocks cytokine signaling, modulating itch, allergy, and inflammatory responses, immune and therapeutic studies.</p>Formula:C16H17FN6O3Purity:99.36%Color and Shape:SolidMolecular weight:360.35NX-5948
CAS:<p>NX-5948 (BTK-IN-24) is a PROTAC-type BTK degrader with anti-inflammatory and anticancer activities, inhibiting B cell activation.</p>Formula:C42H54N12O5Purity:98.29%Color and Shape:SolidMolecular weight:806.96Erlotinib-d6
CAS:<p>Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .</p>Formula:C22H23N3O4Purity:98%Color and Shape:SolidMolecular weight:399.47LDN-193189 Tetrahydrochloride
CAS:<p>LDN193189 is a BMPI receptor inhibitor, blocking ALK2 and ALK3 effectively, while weak on ALK4, ALK5, ALK7.</p>Formula:C25H26Cl4N6Purity:98.21%Color and Shape:SolidMolecular weight:552.33Bleximenib oxalate
CAS:<p>Bleximenib oxalate (Menin-MLL inhibitor 24 oxalate) is a menin-MLL inhibitor that blocks the binding of the menin-KMT2A complex to chromatin at gene promoters.</p>Formula:C34H52FN7O7Purity:98%Color and Shape:SolidMolecular weight:689.82Pentagamavunon-1
CAS:<p>PGV-1, an oral Curcumin analog, induces apoptosis by inhibiting COX-2, VEGF, and NF-κB activation.</p>Formula:C23H24O3Color and Shape:SolidMolecular weight:348.43Cediranib maleate
CAS:<p>Cediranib maleate (AZD2171 maleate) is a VEGFR2 inhibitor that inhibits Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit.</p>Formula:C29H31FN4O7Color and Shape:SolidMolecular weight:566.58N-piperidine Ibrutinib hydrochloride
CAS:<p>N-piperidine Ibrutinib hydrochloride is a BTK inhibitor that inhibits WT BTK and C481S BTK , which inhibits the growth and proliferation of cancer cells.</p>Formula:C22H23ClN6OPurity:98.83%Color and Shape:SolidMolecular weight:422.91Poseltinib
CAS:<p>Poseltinib is an oral, irreversible BTK inhibitor (IC50 1.95 nM) with higher selectivity over BMX, TEC, and TXK, blocking BCR, FcR, and TLR signaling.</p>Formula:C26H26N6O3Color and Shape:SolidMolecular weight:470.52EW-7195
CAS:<p>EW-7195 inhibits ALK5/TGFβR1 (>300x selective over p38α) with 4.83 nM IC50, blocking TGF-β1 signaling, EMT, and breast cancer lung metastasis.</p>Formula:C23H18N8Purity:98.76%Color and Shape:SolidMolecular weight:406.44Imatinib D4
CAS:<p>Imatinib D4 is a deuterium-labeled Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, PDGFR, v-Abl, and c-kit kinase activity.</p>Formula:C29H31N7OPurity:98%Color and Shape:SolidMolecular weight:497.63Surfen dihydrochloride
CAS:<p>Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a heparin sulfate antagonist with antimicrobial properties and inhibits blockade of signaling.</p>Formula:C21H22Cl2N6OPurity:97.08%Color and Shape:SolidMolecular weight:445.35Gefitinib-d8
CAS:<p>Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib D8 is a deuterium labeled Gefitinib.</p>Formula:C22H24ClFN4O3Purity:98%Color and Shape:SolidMolecular weight:454.95Ribociclib-d6
CAS:<p>Ribociclib-d6 is a deuterated compound of Ribociclib (LEE011) for isotope tracing.Ribociclib is an orally available CDK4/6 inhibitor with antitumor activity.</p>Formula:C23H30N8OColor and Shape:SolidMolecular weight:440.57Disitamab
CAS:<p>Disitamab (RC48-0) is a humanized anti-HER2 monoclonal antibody used in ADC synthesis.</p>Purity:95.00%Color and Shape:LiquidAflibercept
CAS:<p>Aflibercept has a wide range of applications in life science related research.</p>Color and Shape:LiquidKG-548
CAS:<p>KG-548 is a dual inhibitor of ARNT/TACC3 and HIF-1α, inhibiting lactate production, and can be used in cancer research.</p>Formula:C9H4F6N4Purity:99.62%Color and Shape:SolidMolecular weight:282.15SM1-71
CAS:<p>SM1-71 is a TAK1 inhibitor that inhibits MKNK2 and RSK2.SM1-71 acts as a kinase probe with anticancer activity.</p>Formula:C24H26ClN7OPurity:96%Color and Shape:SolidMolecular weight:463.96Elsubrutinib
CAS:<p>Elsubrutinib (ABBV-105) is a highly active, potent, and selective orally-administered inhibitor of Bruton's tyrosine kinase (BTK). It irreversibly inhibits the catalytic domain of BTK with an IC50 value of 0.18 μM. Elsubrutinib holds potential for the advancement of research on inflammatory diseases.</p>Formula:C17H19N3O2Color and Shape:SolidMolecular weight:297.358Itacitinib adipate
CAS:<p>Itacitinib adipate: oral JAK1 inhibitor, tested in phase II myelofibrosis trial.</p>Formula:C32H33F4N9O5Color and Shape:SolidMolecular weight:699.66Conteltinib tetrahydrochloride
<p>Conteltinibtetrahydrochloride (CT-707 tetrahydrochloride) is the tetrahydrochloride form of Conteltinib. It acts as an inhibitor for FAK (IC50=1.6 nM), ALK, and Pyk2. When used in combination with Cabozantinib, Conteltinib tetrahydrochloride exhibits a synergistic antitumor effect.</p>Formula:C32H49Cl4N9O3SColor and Shape:SolidMolecular weight:781.667Afatinib D6
CAS:<p>Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor.</p>Formula:C24H25ClFN5O3Color and Shape:SolidMolecular weight:491.98Regorafenib-d3
CAS:<p>Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase.</p>Formula:C21H15ClF4N4O3Purity:98%Color and Shape:SolidMolecular weight:485.83
