Angiogenesis
Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.
Subcategories of "Angiogenesis"
- BTK(145 products)
- Bcr-Abl(102 products)
- EGFR(572 products)
- FAK(72 products)
- FLT(92 products)
- Fibroblast Growth Factor Receptor (FGFR)(170 products)
- JAK(245 products)
- PDGFR(126 products)
- RAAS(86 products)
- Src(78 products)
- Syk(38 products)
- Thrombin(47 products)
- VDA(2 products)
- VEGFR(268 products)
Show 6 more subcategories
Found 1414 products of "Angiogenesis"
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Disitamab
CAS:<p>Disitamab (RC48-0) is a humanized anti-HER2 monoclonal antibody used in ADC synthesis.</p>Purity:95.00%Color and Shape:LiquidImatinib D4
CAS:<p>Imatinib D4 is a deuterium-labeled Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, PDGFR, v-Abl, and c-kit kinase activity.</p>Formula:C29H31N7OPurity:98%Color and Shape:SolidMolecular weight:497.63Poseltinib
CAS:<p>Poseltinib is an oral, irreversible BTK inhibitor (IC50 1.95 nM) with higher selectivity over BMX, TEC, and TXK, blocking BCR, FcR, and TLR signaling.</p>Formula:C26H26N6O3Color and Shape:SolidMolecular weight:470.52KG-548
CAS:<p>KG-548 is a dual inhibitor of ARNT/TACC3 and HIF-1α, inhibiting lactate production, and can be used in cancer research.</p>Formula:C9H4F6N4Purity:99.62%Color and Shape:SolidMolecular weight:282.15SM1-71
CAS:<p>SM1-71 is a TAK1 inhibitor that inhibits MKNK2 and RSK2.SM1-71 acts as a kinase probe with anticancer activity.</p>Formula:C24H26ClN7OPurity:96%Color and Shape:SolidMolecular weight:463.96Itacitinib adipate
CAS:<p>Itacitinib adipate: oral JAK1 inhibitor, tested in phase II myelofibrosis trial.</p>Formula:C32H33F4N9O5Color and Shape:SolidMolecular weight:699.66Aflibercept
CAS:<p>Aflibercept has a wide range of applications in life science related research.</p>Color and Shape:LiquidBI-3663
CAS:<p>BI-3663 is a selective PTK2/FAK PROTAC with cereblon ligands, degrading PTK2 (IC50: 18 nM), and shows anti-cancer properties.</p>Formula:C44H42F3N7O12Purity:98%Color and Shape:SolidMolecular weight:917.84Lestaurtinib
CAS:<p>Lestaurtinib (CEP 701) is a FLT3 inhibitor that inhibits the phosphorylation of RPTKs and can be used to study leukemia.</p>Formula:C26H21N3O4Purity:99.17%Color and Shape:Off-White SolidMolecular weight:439.46GMB-475
CAS:<p>GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.</p>Formula:C43H46F3N7O7SPurity:98.78% - >99.99%Color and Shape:SolidMolecular weight:861.93Gefitinib-based PROTAC 3
CAS:<p>Gefitinib-PROTAC 3 degrades EGFR in cancer cells; DC50s: 11.7 nM (HCC827) and 22.3 nM (H3255).</p>Formula:C47H57ClFN7O8SPurity:97.29% - 98.25%Color and Shape:SolidMolecular weight:934.51N-piperidine Ibrutinib
CAS:<p>N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively.</p>Formula:C22H22N6OPurity:96.65%Color and Shape:SolidMolecular weight:386.45DGY-06-116
CAS:<p>DGY-06-116 is an selective and irreversible covalent inhibitor of Src and FGFR1 with IC50 value of 3nM and 8340 nM, respectively.</p>Formula:C32H33ClN8O2Purity:97.65%Color and Shape:SolidMolecular weight:597.11Dasatinib N-oxide
CAS:<p>Dasatinib N-oxide is a key metabolite and potential impurity of the kinase inhibitor dasatinib.</p>Formula:C22H26ClN7O3SPurity:98.54% - 99.94%Color and Shape:SolidMolecular weight:504UF010
CAS:<p>UF010 is a potent and selective HADC inhibitor with IC50 ~0.06 μM, 0.1 μM, 0.5 μM and 1.5 μM for HDACs 3, 2, 1 and 8, respectively.</p>Formula:C11H15BrN2OPurity:98.03% - 99.68%Color and Shape:SolidMolecular weight:271.15AMG-47a
CAS:<p>AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.</p>Formula:C29H28F3N5O2Purity:98%Color and Shape:SolidMolecular weight:535.56Merestinib dihydrochloride
CAS:<p>Merestinib dihydrochloride (LY2801653 dihydrochloride) is a kinase inhibitor with antitumor activity that inhibits MET and MKNK1/2.</p>Formula:C30H24Cl2F2N6O3Color and Shape:SolidMolecular weight:625.45NVP-BAW2881
CAS:<p>NVP-BAW2881 (BAW2881) is a potent and selective VEGFR inhibitor with activity to inhibit chronic and acute skin inflammation.</p>Formula:C22H15F3N4O2Purity:98.19% - 99.97%Color and Shape:SolidMolecular weight:424.38SKLB4771
CAS:<p>SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.</p>Formula:C25H27N7O3S2Purity:98% - >99.99%Color and Shape:SolidMolecular weight:537.66OICR-9429
CAS:<p>OICR-9429 blocks WDR5 binding to MLL/Histone 3, hindering acute myeloid leukemia cell growth in vitro.</p>Formula:C29H32F3N5O3Purity:97.07% - 99.93%Color and Shape:SolidMolecular weight:555.59Arnebin 1
CAS:<p>(Rac)-Arnebin 1 (beta, beta-dimethylacrylshikonin) has anti-tumor, anti-inflammatory, anti-immune deficiency and protecting liver.</p>Formula:C21H22O6Purity:98.76% - 99.81%Color and Shape:SolidMolecular weight:370.396A 83-01
CAS:<p>A 83-01 (ALK5 Inhibitor IV) is a selective inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7.</p>Formula:C25H19N5SPurity:97% - 98.2%Color and Shape:SolidMolecular weight:421.52PX-478
CAS:<p>PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.</p>Formula:C13H20Cl4N2O3Purity:97% - 99.79%Color and Shape:SolidMolecular weight:394.12Pantoprazole sodium
CAS:<p>Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.</p>Formula:C16H14F2N3NaO4SPurity:96.92% - 99.81%Color and Shape:White To Off-White SolidMolecular weight:405.35GluR6 antagonist-1
CAS:<p>GluR6 antagonist-1 inhibits the pY binding site of tyrosine kinase p56lck SH2 domain.</p>Formula:C15H11ClN2OSPurity:99.89%Color and Shape:SolidMolecular weight:302.78Avitinib
CAS:<p>Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,</p>Formula:C26H26FN7O2Purity:99.81% - >99.99%Color and Shape:SolidMolecular weight:487.53Radotinib
CAS:<p>Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notably</p>Formula:C27H21F3N8OPurity:99.13% - 99.97%Color and Shape:SolidMolecular weight:530.52,4-DPD
CAS:<p>2,4-DPD is competitive inhibitor of the oxygen-sensing enzyme HIF-α prolyl hydroxylase (HIF-PH)</p>Formula:C11H13NO4Purity:99.74%Color and Shape:Yellow Solid CrystallineMolecular weight:223.232-(1,8-naphthyridin-2-yl)phenol
CAS:<p>2-NP is a STAT1 enhancer.</p>Formula:C14H10N2OPurity:99.33% - 99.82%Color and Shape:SolidMolecular weight:222.24Syk Inhibitor II dihydrochloride
CAS:<p>Syk inhibitor II selectively blocks Syk (IC50 = 41 nM), impacting platelet function and inflammation, with lower potency against other kinases.</p>Formula:C14H17Cl2F3N6OPurity:98.53%Color and Shape:SolidMolecular weight:413.22Tropisetron
CAS:<p>Tropisetron (ICS 205-930) is an α7-nicotinic receptor agonist and 5-HT3 receptor antagonist with Kis of 6.9 nM and 5.3 nM, respectively.</p>Formula:C17H20N2O2Purity:99.68%Color and Shape:White SolidMolecular weight:284.35Bisindolylmaleimide I
CAS:<p>Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.</p>Formula:C25H24N4O2Purity:98.19% - 98.75%Color and Shape:Orange SolidMolecular weight:412.48A 83-01 sodium salt
CAS:<p>A 83-01 sodium salt inhibits ALK5, ALK4, and ALK7 kinases with IC50s: 12, 45, 7.5 nM.</p>Formula:C25H19N5NaSColor and Shape:SolidMolecular weight:444.51Protein kinase inhibitor 6
CAS:<p>Protein kinase inhibitor 6 is a protein kinase inhibitor.</p>Formula:C13H9FN2SPurity:98.01%Color and Shape:SolidMolecular weight:244.29NCGC00262650
CAS:<p>NCGC00262650 is an inhibitor of AMA1-RON2 interaction and c-Src tyrosine kinase activity.</p>Formula:C18H20N4OPurity:98%Color and Shape:SolidMolecular weight:308.38Midostaurin
CAS:<p>PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.</p>Formula:C35H30N4O4Purity:97.61% - >99.99%Color and Shape:SolidMolecular weight:570.64MCB-613
CAS:<p>MCB-613 is an effective steroid receptor coactivator (SRC) stimulator.</p>Formula:C20H20N2OPurity:98.17% - 99.754%Color and Shape:SolidMolecular weight:304.39Takeda-6d
CAS:<p>Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.</p>Formula:C27H19ClFN5O3SPurity:98.27%Color and Shape:SolidMolecular weight:547.99Vorolanib
CAS:<p>Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.</p>Formula:C23H26FN5O3Purity:97.35%Color and Shape:SolidMolecular weight:439.48Regorafenib mesylate
CAS:<p>Regorafenib mesylate is an oral multi-kinase inhibitor targeting VEGFR, PDGFRβ, Kit, RET, Raf-1 with strong anti-tumor and anti-angiogenic effects.</p>Formula:C22H19ClF4N4O6SColor and Shape:SolidMolecular weight:578.92BMS817378
CAS:<p>BMS817378 is a potent and selective inhibitor of MET(IC50 : 1.7 nM).</p>Formula:C24H18ClF2N4O7PPurity:>99.99%Color and Shape:SolidMolecular weight:578.85Nastorazepide
CAS:<p>Nastorazepide is a selective, orally available antagonist of gastrin/cholecystokinin 2 (CCK-2) receptor with potential antineoplastic activity.</p>Formula:C29H36N4O5Purity:99.83%Color and Shape:SolidMolecular weight:520.62SPHINX31
CAS:<p>SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).</p>Formula:C27H24F3N5O2Purity:98.81% - 99.3%Color and Shape:SolidMolecular weight:507.51Ibuprofen Lysine
CAS:<p>Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.</p>Formula:C19H32N2O4Purity:99.26%Color and Shape:CoaMolecular weight:352.47Benidipine hydrochloride
CAS:<p>Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.</p>Formula:C28H32ClN3O6Purity:99.80%Color and Shape:SolidMolecular weight:542.031-Naphthyl PP1
CAS:<p>1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)</p>Formula:C19H19N5Purity:99.85%Color and Shape:White Cyrstalline SolidMolecular weight:317.39Regorafenib monohydrate
CAS:<p>Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine</p>Formula:C21H17ClF4N4O4Purity:99.69%Color and Shape:SolidMolecular weight:500.83AZD3759 hydrochloride
CAS:<p>AZD3759 hydrochloride is an oral, CNS-penetrant EGFR inhibitor with IC50s of 0.2/0.3/0.2 nM.</p>Formula:C22H24Cl2FN5O3Purity:99.62%Color and Shape:SolidMolecular weight:496.36SU 4313
CAS:<p>SU 4313 is a bioactive chemical.</p>Formula:C18H17NOPurity:99.51% - 99.89%Color and Shape:SolidMolecular weight:263.33Gefitinib dihydrochloride
CAS:<p>Gefitinib dihydrochloride: orally active, selective EGFR inhibitor (IC50: 33-54 nM), hinders tumor growth, induces autophagy and apoptosis in cancer research.</p>Formula:C22H26Cl3FN4O3Color and Shape:SolidMolecular weight:519.82
