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Angiogenesis

Angiogenesis

Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.

Subcategories of "Angiogenesis"

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Found 1522 products of "Angiogenesis"

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  • VEGFR2/HDAC1-IN-1


    <p>VEGFR2/HDAC1-IN-1 (compound 13) is a potent dual inhibitor of VEGFR-2 and HDAC, with IC50 values of 57.83 nM for VEGFR-2 and 9.82 nM for HDAC.</p>
    Purity:98%
    Color and Shape:Odour Solid
  • FLT3-IN-20


    <p>FLT3-IN-20 (compound 34f) is a potent FLT3 inhibitor, demonstrating IC50 values of 1 nM for FLT3-D835Y and 4 nM for FLT3-ITD.</p>
    Formula:C28H33N7O2S
    Color and Shape:Solid
    Molecular weight:531.67
  • AT-533

    CAS:
    <p>AT-533 inhibits Hsp90, HSV, hinders HIF-1α/VEGF/VEGFR-2, Erk1/2, FAK, Akt/mTOR/p70S6K, and blocks tumor growth, angiogenesis, and HUVEC activities.</p>
    Formula:C23H30N4O3
    Purity:99.67%
    Color and Shape:Soild
    Molecular weight:410.51
  • EGFR-IN-15

    CAS:
    <p>EGFR-IN-15 (compound I-005) is a potent EGFR inhibitor, exhibiting an IC50 value of 4 nM. This compound holds potential for oncological research applications.</p>
    Formula:C24H25BrN6O2
    Color and Shape:Solid
    Molecular weight:509.408
  • JAK-IN-15

    CAS:
    <p>JAK-IN-15 is a JAK inhibitor. WO2016119700A1 (Compound 15).</p>
    Formula:C22H23FN4O3S
    Color and Shape:Solid
    Molecular weight:442.51
  • DSPE-PEG2000-A7R


    <p>DSPE-PEG2000-A7R is a PEG compound consisting of DSPE and a tumor vasculature-targeting peptide (A7R). A7R exhibits high affinity and specificity for VEGFR-2, a receptor that is overexpressed in various tumors.</p>
    Color and Shape:Odour Solid
  • SJF 1521

    CAS:
    <p>SJF 1521 is an EGFR degrader belonging to the PROTAC class that selectively degrades EGFR while preserving HER2.</p>
    Formula:C57H61ClFN7O9S
    Purity:99.20%
    Color and Shape:Solid
    Molecular weight:1074.65
  • EGFR-IN-83


    <p>EGFR-IN-83 (Compound 9), an EGFR inhibitor with an IC50 of 2.53 nM, exhibits antiproliferative effects on MCF-7 and MDA-MB-231 cell lines, with respective IC50</p>
    Formula:C22H17F3N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:410.39
  • Multi-kinase-IN-4


    <p>Multi-kinase-IN-4 (compound 5d) is a multi-targeted kinase inhibitor active against VEGFR2, EGFR, HER2, and CDK2, with respective IC50 values of 0.33, 0.22, 0.</p>
    Formula:C21H20ClFN2OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:402.91
  • MET/PDGFRA-IN-2


    <p>MET/PDGFRA-IN-2 (compound 8h) serves as an inhibitor of MET and PDGFRA proteins, promoting apoptosis in cells and impeding the proliferation of MET-positive</p>
    Formula:C29H29N7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:491.59
  • AST5902

    CAS:
    <p>AST5902 is the active metabolite of Alflutinib.</p>
    Formula:C27H29F3N8O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:554.57
  • SNIPER(ABL)-039

    CAS:
    <p>SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of</p>
    Formula:C54H68ClN11O9S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1114.77
  • RR-src

    CAS:
    Tyrosine kinase substrate peptide
    Formula:C64H106N22O21
    Purity:98%
    Color and Shape:Lyophilized Powder
    Molecular weight:1519.66
  • Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine

    CAS:
    <p>Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine: an ISAC with anti-HER2, STING agonist ADU-S100, linker; for cancer research.</p>
    Formula:C51H65N17O19P2S2·xC6H15N
    Color and Shape:Solid
    Molecular weight:1447.44
  • hCA/VEGFR-2-IN-2


    <p>Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII and</p>
    Formula:C23H26N6O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:498.55
  • Varlitinib Tosylate

    CAS:
    <p>Varlitinib Tosylate is a selective and potent inhibitor of ErbB1(EGFR) and ErbB2(HER2).</p>
    Formula:C36H35ClN6O8S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:811.34
  • JAK 3 inhibitor IV

    CAS:
    <p>JAK 3 inhibitor IV (ZM 39923 hydrochloride) is a JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to</p>
    Formula:C16H19NO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:241.33
  • FDU73


    <p>FDU73 is a potent and selective BTK PROTAC degrader with a DC50 of 2.9 nM in JeKo-1 cells. It inhibits tumor cell proliferation and exhibits antitumor activity.</p>
    Color and Shape:Odour Solid
  • hCA/VEGFR-2-IN-4


    <p>hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/</p>
    Formula:C22H23FN6O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:502.52
  • VEGFR/PARP-IN-1


    <p>VEGFR/PARP-IN-1 (Compound 14b) is a dual inhibitor of VEGFR and PARP with IC50 values of 191 nM and 60.9 nM, respectively.</p>
    Formula:C29H27N9O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:517.58