Angiogenesis
Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.
Subcategories of "Angiogenesis"
- BTK(162 products)
- Bcr-Abl(117 products)
- EGFR(593 products)
- FAK(72 products)
- FLT(90 products)
- Fibroblast Growth Factor Receptor (FGFR)(183 products)
- JAK(247 products)
- PDGFR(127 products)
- RAAS(90 products)
- Src(81 products)
- Syk(37 products)
- Thrombin(53 products)
- VDA(2 products)
- VEGFR(245 products)
Show 6 more subcategories
Found 2156 products of "Angiogenesis"
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DMH4
CAS:DMH4 is a potent and selective inhibitor of VEGFR2 with an IC50 of 0.16 µM.Formula:C24H24N4O2Purity:99.58%Color and Shape:SolidMolecular weight:400.47FLT3/ITD-IN-2
CAS:FLT3/ITD-IN-2: Powerful FLT3/ITD, FLT3D835Y, and FLT3 inhibitor; hinders AML cell growth. IC50s: 0.3-1.0 nM.Formula:C23H26F3N7O2Color and Shape:SolidMolecular weight:489.49RG 14921
CAS:RG 14921 is a pyridone analog of erbstatin, epidermal growth factor (EGF) receptor tyrosine kinase, and cAMP-dependent kinase.Formula:C11H9NO3Color and Shape:SolidMolecular weight:203.19OXSI-2
CAS:OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.Formula:C18H15N3O3SPurity:98%Color and Shape:Dark Orange SolidMolecular weight:353.39TK4b
CAS:TK4b, a JAK inhibitor, targets leukemia/lymphoid diseases, with IC50s: 18.42 nM (JAK3) & 19.40 nM (JAK2).Formula:C21H22N2O2Color and Shape:SolidMolecular weight:334.41TOP1210
CAS:TOP1210, a narrow spectrum kinase inhibitor, potently inhibits P38α, Src, and Syk kinase activities.Formula:C45H48N8O6Color and Shape:SolidMolecular weight:796.91TX-1918
CAS:TX-1918, a tyrphostin, blocks eEF-2K to hinder HepG2, HCT116 cell growth.Formula:C14H12O3Color and Shape:SolidMolecular weight:228.24JAK-IN-20
CAS:JAK-IN-20: potent oral JAK1,2,3 inhibitor with IC50s 7, 5, 14 nM respectively, good pharmacokinetics, anti-inflammatory in vivo.Formula:C28H30FN7O2Color and Shape:SolidMolecular weight:515.58Peficitinib hydrochloride
CAS:Peficitinib HCl (ASP015K) is an oral JAK inhibitor with IC50s: JAK1 (3.9 nM), JAK2 (5.0 nM), JAK3 (0.7 nM), Tyk2 (4.8 nM).Formula:C18H23ClN4O2Color and Shape:SolidMolecular weight:362.86BTK inhibitor 10
CAS:BTK inhibitor 10, an oral drug from patent WO2018145525, may treat rheumatoid arthritis.Formula:C25H23N5O3Purity:98%Color and Shape:SolidMolecular weight:441.48J-1048
CAS:J-1048, an activin receptor-like kinase 5 (ALK5) inhibitor, effectively suppresses TAA-induced liver fibrosis in mice through specific inhibition of the TGF-β/Formula:C23H17FN6S2Color and Shape:SolidMolecular weight:460.55DBPR112
CAS:DBPR112: oral furanopyrimidine EGFR inhibitor; IC50: 15 nM (EGFRWT), 48 nM (L858R/T790M); blocks ATP site, strong antitumor effects.Formula:C32H31N5O3Purity:99.25%Color and Shape:SolidMolecular weight:533.62Antiproliferative agent-34
CAS:Antiproliferative Agent-34 (Compound A14), a multitarget kinase inhibitor, demonstrates IC50 values of 177 nM for EGFR L858R/T790M and 1567 nM for EGFR WT.Formula:C27H27N7O5Purity:98%Color and Shape:SolidMolecular weight:529.55Flonoltinib
CAS:<p>Flonoltinib (JAK2/FLT3-IN-1) is an orally active and efficient JAK2/FLT3 inhibitor with anti-cancer properties.</p>Formula:C25H34FN7OPurity:99.52%Color and Shape:SolidMolecular weight:467.58SJF620
CAS:SJF620 is a potent degrader of PROTAC BTK(DC50 : 7.9 nM).Formula:C41H44N8O7Purity:98%Color and Shape:SolidMolecular weight:760.84FGFR-IN-13
CAS:FGFR-IN-13 (compound III-30), an irreversible covalent inhibitor of the fibroblast growth factor receptor (FGFR), effectively modulates signaling through FGFR1 (IC 50 = 0.20 ± 0.02 nM) and FGFR4 (IC 50 = 0.40 ± 0.03 nM). It suppresses the expression of crucial proteins such as total-PARP and Bcl-2, while enhancing the expression of Cleaved-PARP and Bax in a dose-dependent manner. Notably, FGFR-IN-13 demonstrates considerable antitumor and oral activity [1].Formula:C23H21N5O3Molecular weight:415.44Zotiraciclib HCl
CAS:Zotiraciclib (TG02/SB1317) is a CDK/JAK2/FLT3 inhibitor potentially treating Myc-overexpressing cancers, including glioblastoma.Formula:C23H26Cl2N4OColor and Shape:SolidMolecular weight:445.388CJ-2360
CAS:CJ-2360 is a potent ALK inhibitor, effective on wild-type and various mutants, with IC50 values ranging from 2.2 to 8.9 nM, also targeting 468 kinases.Formula:C27H30FN5O2Color and Shape:SolidMolecular weight:475.56AMG-Tie2-1
CAS:AMG-Tie2-1 is a Tie2 and VEGFR2 inhibitor with anticancer and antitumor activity for the study of cardiovascular disease and cancer.Formula:C25H20F3N5O2Purity:98.9%Color and Shape:SolidMolecular weight:479.45Infigratinib phosphate
CAS:Infigratinib phosphate (BGJ-398 phosphate) is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, andFormula:C26H34Cl2N7O7PPurity:99.24% - 99.6%Color and Shape:SolidMolecular weight:658.47
