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Angiogenesis

Angiogenesis

Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.

Subcategories of "Angiogenesis"

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Found 2141 products of "Angiogenesis"

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  • EGFR-IN-32

    CAS:
    EGFR-IN-32, a potent EGFR blocker, shows promise for EGFR-mutated illnesses. (Patent WO2021185297A1, compound 2)
    Formula:C31H34N6O3
    Color and Shape:Solid
    Molecular weight:538.64
  • TCJL37

    CAS:
    TCJL37: potent, selective TYK2 inhibitor (K i 1.6 nM), oral, for IBD research.
    Formula:C17H11ClF2N4O2
    Color and Shape:Solid
    Molecular weight:376.74
  • CT-721

    CAS:
    CT-721: potent, time-bound Bcr-Abl inhibitor, IC50 21.3 nM, effective against CML.
    Formula:C30H29ClN6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:525.04
  • VEGFR-2-IN-37

    CAS:
    VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM.
    Formula:C18H16N2O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.4
  • Upadacitinib tartrate

    CAS:
    Upadacitinib: potent, selective JAK1 inhibitor, 74x preferential to JAK2, effective in rat arthritis.
    Formula:C21H33F3N6O11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:602.521
  • TL02-59

    CAS:
    TL02-59: Fgr inhibitor (IC50=0.03nM), also targets Lyn (0.1nM), Hck (160nM), halts acute myelogenous leukemia growth.
    Formula:C32H34F3N5O4
    Purity:98.77%
    Color and Shape:Solid
    Molecular weight:609.64
  • NMS-P953

    CAS:
    NMS-P953: JAK2 inhibitor, reduces tumor growth in SET-2 model, confirmed in vivo action, good pharmacokinetics and safety.
    Formula:C16H11ClF3N5O
    Color and Shape:Solid
    Molecular weight:381.74
  • Rocbrutinib

    CAS:
    Rocbrutinib is a Bruton's tyrosine kinase (BTK) inhibitor that exhibits antineoplastic properties [1].
    Formula:C42H51N9O5
    Color and Shape:Solid
    Molecular weight:761.91
  • BEBT-109

    CAS:
    BEBT-109 is a selective epidermal growth factor receptor (EGFR) inhibitor that shows anti-tumor activity in EGFR-mutant non-small cell lung cancer.
    Formula:C27H32N8O3
    Purity:97.26%
    Color and Shape:Solid
    Molecular weight:516.6
  • EGFR-IN-30

    CAS:
    EGFR-IN-30 is an EGFR inhibitor (IC50: 1-10 nM, <1 nM WT/mutants) with potential in cancer research.
    Formula:C28H33BrN7O2P
    Color and Shape:Solid
    Molecular weight:610.49
  • UNC4203

    CAS:
    UNC4203 inhibits MERTK (1.2 nM), AXL (140 nM), TYRO3 (42 nM), FLT3 (90 nM); potent, selective, oral.
    Formula:C30H44N6O
    Color and Shape:Solid
    Molecular weight:504.71
  • PonatiLink-1-24

    CAS:
    Ponatinib, also known as PonatiLink-1-24, is a selective inhibitor of the Abelson murine leukemia (ABL) enzyme [1].
    Formula:C101H144ClF5N12O29
    Color and Shape:Solid
    Molecular weight:2120.73
  • BMS-599626 Hydrochloride

    CAS:
    BMS-599626 HCl (AC480 HCl) is an oral inhibitor of HER1, HER2, HER4 kinases, potentially blocking tumor growth. IC50: 22/32/190 nM.
    Formula:C27H28ClFN8O3
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:567.01
  • FGFR-IN-8

    CAS:
    FGFR-IN-8, potent oral FGFR inhibitor for wild-type/mutant types, induces apoptosis with anti-cancer properties.
    Formula:C27H31Cl2N9O2
    Color and Shape:Solid
    Molecular weight:584.5
  • ALK/EGFR-IN-2

    CAS:
    ALK/EGFR-IN-2 is a potent dual inhibitor targeting ALK and EGFR, promoting apoptosis and G0/G1 cell cycle arrest in cancer cells.
    Formula:C27H34ClN7O3S
    Color and Shape:Solid
    Molecular weight:572.12
  • VEGFR-2-IN-9

    CAS:
    VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer.
    Formula:C23H25N3O3
    Purity:97.19%
    Color and Shape:Solid
    Molecular weight:391.46
  • PF-06459988

    CAS:
    PF-06459988 is a novel, effective, orally active, irreversible, and selective epidermal growth factor receptor (EGFR) mutant inhibitor.
    Formula:C19H22ClN7O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:431.88
  • Lepzacitinib

    CAS:
    Lepzacitinib is a selective, inflammatory, small molecule JAK1/3(Janus kinase) inhibitor primarily used for the treatment of atopic dermatitis.
    Formula:C18H21N5O3
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:355.39
  • EGFR/CSC-IN-1

    CAS:
    EGFR/CSC-IN-1 is a dual inhibitor targeting both the epidermal growth factor receptor (EGFR [IC50 10.52 nM]) and cancer stem cells (CSC), with potential
    Formula:C54H54Cl2FN7O7S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1067.08
  • EGFR-IN-87

    CAS:
    EGFR-IN-87 is an EGFR tyrosine kinase inhibitor with potent inhibitory activity, exhibiting IC50 values of 3.1 nM, 1.3 nM, and 7.1 nM against EGFR_d746-750,
    Formula:C28H33N7O2
    Purity:98.64%
    Color and Shape:Solid
    Molecular weight:499.61