Bcr-Abl
Bcr-Abl inhibitors are targeted therapies that inhibit the Bcr-Abl fusion protein, which is formed due to the Philadelphia chromosome translocation and is a driver of chronic myeloid leukemia (CML). This protein also influences angiogenesis, contributing to tumor progression. Bcr-Abl inhibitors are crucial in the treatment of CML and are being explored for their potential in inhibiting angiogenesis in various cancers. At CymitQuimica, we provide high-quality Bcr-Abl inhibitors to support your research in cancer biology, angiogenesis, and targeted therapy.
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Vodobatinib
CAS:1388803-90-4
Vodobatinib (K-0706) is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 …
Formula:
C27H20ClN3O2
Purity:
99.55%
Color and Shape:
Solid
Molecular weight:
453.92
Ref: TM-T8882
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 213.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 517.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Flumatinib mesylate
CAS:895519-91-2
Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes …
Formula:
C30H33F3N8O4S
Purity:
99.82%
Color and Shape:
Solid
Molecular weight:
658.69
Ref: TM-T7861
| 1mg | 37.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 131.00 € | ||
| 25mg | 247.00 € | ||
| 50mg | 388.00 € | ||
| 100mg | 621.00 € | ||
| 500mg | 1,285.00 € | ||
| 1mL*10mM (DMSO) | 138.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Radotinib
CAS:926037-48-1
Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for …
Formula:
C27H21F3N8O
Purity:
99.39% - 99.97%
Color and Shape:
Solid
Molecular weight:
530.5
Ref: TM-T2328
| 5mg | 46.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 118.00 € | ||
| 50mg | 185.00 € | ||
| 100mg | 346.00 € | ||
| 500mg | 807.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
GNF-7
CAS:839706-07-9
GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 …
Formula:
C28H24F3N7O2
Purity:
97.05% - 99.47%
Color and Shape:
Solid
Molecular weight:
547.53
Ref: TM-T3196
| 1mg | 44.00 € | ||
| 5mg | 99.00 € | ||
| 10mg | 147.00 € | ||
| 25mg | 283.00 € | ||
| 50mg | 424.00 € | ||
| 100mg | 677.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Degrasyn
CAS:856243-80-6
Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S …
Formula:
C19H18BrN3O
Purity:
98.32% - 99.98%
Color and Shape:
Solid
Molecular weight:
384.27
Ref: TM-T6300
| 5mg | 63.00 € | ||
| 10mg | 100.00 € | ||
| 25mg | 195.00 € | ||
| 50mg | 352.00 € | ||
| 100mg | 522.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Nocodazole
CAS:31430-18-9
Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.
Formula:
C14H11N3O3S
Purity:
98% - 99.91%
Color and Shape:
Physical Description White Powder (Ntp 1992)
Molecular weight:
301.32
Ref: TM-T2802
| 5mg | 36.00 € | ||
| 10mg | 54.00 € | ||
| 25mg | 97.00 € | ||
| 50mg | 171.00 € | ||
| 100mg | 276.00 € | ||
| 200mg | 412.00 € | ||
| 500mg | 669.00 € | ||
| 1mL*10mM (DMSO) | 40.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Gypsogenin
CAS:639-14-5
Gypsogenin (639-14-5) is a naturally occurring biochemical that shows anti-ABL1 kinase and anti-chronic Myelogenous Leukemia …
Formula:
C30H46O4
Purity:
99.73%
Color and Shape:
Solid
Molecular weight:
470.68
Ref: TM-T25476
| 1mg | 132.00 € | ||
| 5mg | 309.00 € | ||
| 10mg | 458.00 € | ||
| 25mg | 737.00 € | ||
| 50mg | 1,047.00 € | ||
| 100mg | 1,384.00 € | ||
| 1mL*10mM (DMSO) | 348.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Rebastinib
CAS:1020172-07-9
DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and …
Formula:
C30H28FN7O3
Purity:
99.53% - 99.84%
Color and Shape:
Solid
Molecular weight:
553.59
Ref: TM-T2640
| 2mg | 47.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 169.00 € | ||
| 50mg | 247.00 € | ||
| 100mg | 370.00 € | ||
| 200mg | 557.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Ponatinib
CAS:943319-70-8
Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, …
Formula:
C29H27F3N6O
Purity:
98% - 99.74%
Color and Shape:
Solid
Molecular weight:
532.56
Ref: TM-T2372
| 10mg | 54.00 € | ||
| 50mg | 69.00 € | ||
| 100mg | 97.00 € | ||
| 200mg | 136.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
AT9283
CAS:896466-04-9
AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, …
Formula:
C19H23N7O2
Purity:
99.87% - 99.98%
Color and Shape:
Solid
Molecular weight:
381.43
Ref: TM-T3068
| 1mg | 46.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 167.00 € | ||
| 25mg | 294.00 € | ||
| 50mg | 488.00 € | ||
| 100mg | 711.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Multi-kinase inhibitor 1
CAS:778274-97-8
Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.
Formula:
C20H17F3N4O3
Purity:
99.34%
Color and Shape:
Solid
Molecular weight:
418.37
Ref: TM-T4191
| 1mg | 39.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 230.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 505.00 € | ||
| 1mL*10mM (DMSO) | 90.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Flumatinib
CAS:895519-90-1
Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.
Formula:
C29H29F3N8O
Purity:
99.52% - 99.95%
Color and Shape:
Solid
Molecular weight:
562.59
Ref: TM-T4320
| 1mg | 35.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 124.00 € | ||
| 50mg | 160.00 € | ||
| 100mg | 267.00 € | ||
| 200mg | 402.00 € | ||
| 500mg | 666.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
AG1024
CAS:65678-07-1
AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).
Formula:
C14H13BrN2O
Purity:
98% - 99.37%
Color and Shape:
Solid
Molecular weight:
305.17
Ref: TM-T2693
| 2mg | 41.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 157.00 € | ||
| 50mg | 233.00 € | ||
| 100mg | 351.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Olverembatinib dimesylate
CAS:1421783-64-3
Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).
Formula:
C29H27F3N6O·2CH4O3S
Purity:
100% - 99.81%
Color and Shape:
Solid
Molecular weight:
724.77
Ref: TM-T2429
| 1mg | 39.00 € | ||
| 2mg | 56.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 230.00 € | ||
| 50mg | 317.00 € | ||
| 100mg | 463.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Olverembatinib
CAS:1257628-77-5
Olverembatinib (GZD 824) is an orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT, IC50: 0.34 nM) and …
Formula:
C29H27F3N6O
Purity:
100% - 99.29%
Color and Shape:
Solid
Molecular weight:
532.56
Ref: TM-T3071
| 1mg | 35.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 332.00 € | ||
| 100mg | 525.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
XL228
CAS:898280-07-4
XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM …
Formula:
C22H31N9O
Purity:
99.07%
Color and Shape:
Solid
Molecular weight:
437.54
Ref: TM-T17267
| 1mg | 55.00 € | ||
| 2mg | 77.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 147.00 € | ||
| 25mg | 252.00 € | ||
| 50mg | 384.00 € | ||
| 100mg | 569.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Bafetinib
CAS:859212-16-1
Bafetinib (INNO-406): Dual Bcr-Abl/Lyn inhibitor; IC50: 5.8/19 nM; ineffective against T315I mutant, less on c-Kit/PDGFR.
Formula:
C30H31F3N8O
Purity:
94.16% - 99.68%
Color and Shape:
Solid
Molecular weight:
576.62
Ref: TM-T6311
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 101.00 € | ||
| 25mg | 156.00 € | ||
| 50mg | 185.00 € | ||
| 100mg | 343.00 € | ||
| 200mg | 445.00 € | ||
| 1mL*10mM (DMSO) | 90.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
GNF-5
CAS:778277-15-9
GNF-5, non-ATP Bcr-Abl inhibitor (IC50: 0.22±0.1 uM, wild-type), improves upon GNF-2 with better pharmacokinetics.
Formula:
C20H17F3N4O3
Purity:
98% - 99.98%
Color and Shape:
Solid
Molecular weight:
418.37
Ref: TM-T1803
| 10mg | 35.00 € | ||
| 25mg | 51.00 € | ||
| 50mg | 87.00 € | ||
| 100mg | 114.00 € | ||
| 200mg | 199.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
CZC-8004
CAS:916603-07-1
CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.
Formula:
C17H16FN5
Purity:
99.29%
Color and Shape:
Solid
Molecular weight:
309.34
Ref: TM-T7186
| 1mg | 47.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 294.00 € | ||
| 50mg | 439.00 € | ||
| 100mg | 632.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
Adaphostin
CAS:241127-58-2
Adaphostin (NSC-680410) is a p210Bcr/Abl tyrosine kinase inhibitor with IC50 of 14 μM.
Formula:
C24H27NO4
Purity:
97.31%
Color and Shape:
Solid
Molecular weight:
393.48
Ref: TM-T22553
| 5mg | 71.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 312.00 € | ||
| 100mg | 468.00 € | ||
| 500mg | 998.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
