Bcr-Abl
Bcr-Abl inhibitors are targeted therapies that inhibit the Bcr-Abl fusion protein, which is formed due to the Philadelphia chromosome translocation and is a driver of chronic myeloid leukemia (CML). This protein also influences angiogenesis, contributing to tumor progression. Bcr-Abl inhibitors are crucial in the treatment of CML and are being explored for their potential in inhibiting angiogenesis in various cancers. At CymitQuimica, we provide high-quality Bcr-Abl inhibitors to support your research in cancer biology, angiogenesis, and targeted therapy.
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Nilotinib monohydrochloride monohydrate
CAS:923288-90-8
Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) is significantly potent BCR-ABL against, is a second generation …
Formula:
C28H22F3N7O·HCl·H2O
Purity:
99.93%
Color and Shape:
Solid
Molecular weight:
583.99
Ref: TM-T2147
| 50mg | 39.00 € | ||
| 100mg | 51.00 € | ||
| 200mg | 64.00 € | ||
| 500mg | 114.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
AST 487
CAS:630124-46-8
AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of …
Formula:
C26H30F3N7O2
Purity:
98.17% - 99.56%
Color and Shape:
Solid
Molecular weight:
529.56
Ref: TM-T4053
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 522.00 € | ||
| 500mg | 1,133.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
PD173955
CAS:260415-63-2
PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes …
Formula:
C21H16Cl2N4OS
Purity:
98.52% - 99.28%
Color and Shape:
Solid
Molecular weight:
443.35
Ref: TM-T3063
| 1mg | 47.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 142.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 426.00 € | ||
| 100mg | 640.00 € | ||
| 1mL*10mM (DMSO) | 163.00 € |
Estimated delivery in United States, on Wednesday 18 Dec 2024
PF-06651481-00
CAS:1391063-17-4
PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.
Formula:
C26H29Cl2N5O3
Purity:
95%
Color and Shape:
Solid
Molecular weight:
530.45
Ref: TM-T28374
| 1mg | 40.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 122.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
AN-019
CAS:879507-25-2
AN-019 (NRC-019) is a Bcr-Abl kinase inhibitor with antitumor activity for the study of chronic …
Formula:
C25H17F6N5O
Purity:
98.01%
Color and Shape:
Solid
Molecular weight:
517.43
Ref: TM-T26625
| 1mg | 274.00 € | ||
| 5mg | 675.00 € | ||
| 10mg | 923.00 € | ||
| 25mg | 1,421.00 € | ||
| 50mg | 1,850.00 € | ||
| 100mg | 2,336.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
PPY A
CAS:875634-01-8
PPY A is a potent inhibitor of T315l mutant and wild-type Abl kinase and inhibits …
Formula:
C22H20N4O2
Purity:
98.77%
Color and Shape:
Solid
Molecular weight:
372.42
Ref: TM-T23182
| 1mg | 153.00 € | ||
| 5mg | 369.00 € | ||
| 10mg | 605.00 € | ||
| 25mg | 916.00 € | ||
| 50mg | 1,243.00 € | ||
| 100mg | 1,673.00 € | ||
| 500mg | 3,391.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
PD180970
CAS:287204-45-9
PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 …
Formula:
C21H15Cl2FN4O
Purity:
98.47%
Color and Shape:
Solid
Molecular weight:
429.27
Ref: TM-T23128
| 5mg | 57.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 142.00 € | ||
| 50mg | 206.00 € | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
CpCDPK1/TgCDPK1-IN-1
CAS:1092788-23-2
CpCDPK1/TgCDPK1-IN-1 is a inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic …
Formula:
C18H17N5
Purity:
98.71%
Color and Shape:
Liquid
Molecular weight:
303.36
Ref: TM-T78605
| 1mg | 330.00 € | ||
| 5mg | 906.00 € | ||
| 25mg | 1,373.00 € | ||
| 50mg | 1,848.00 € | ||
| 100mg | 2,334.00 € | ||
| 500mg | 4,617.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
Dasatinib hydrochloride
CAS:854001-07-3
Dasatinib hydrochloride is an oral Src/Bcr-Abl inhibitor with potent antitumor effects, Ki values of 16 …
Formula:
C22H27Cl2N7O2S
Purity:
99.98%
Color and Shape:
Solid
Molecular weight:
524.47
Ref: TM-T22303
| 50mg | 45.00 € | ||
| 100mg | 58.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
Nilotinib hydrochloride
CAS:923288-95-3
Nilotinib HCl (AMN-107 HCl), an oral Bcr-Abl inhibitor, targets neuroinflammation, cognitive issues, and chronic myelogenous …
Formula:
C28H23ClF3N7O
Purity:
100%
Color and Shape:
Solid
Molecular weight:
565.98
Ref: TM-T22378
| 5mg | 47.00 € | ||
| 10mg | 62.00 € | ||
| 25mg | 91.00 € | ||
| 50mg | 133.00 € | ||
| 100mg | 195.00 € | ||
| 500mg | 551.00 € | ||
| 1mL*10mM (DMSO) | 94.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
BCR-ABL-IN-7
CAS:688050-42-2
BCR-ABL-IN-7 is an inhibitor of ABL kinase activity in WT and T315I mutants.BCR-ABL-IN-7 can be …
Formula:
C19H16FN3O3S
Purity:
98.28%
Color and Shape:
Liquid
Molecular weight:
385.41
Ref: TM-T72958
| 5mg | 35.00 € | ||
| 10mg | 48.00 € | ||
| 25mg | 67.00 € | ||
| 50mg | 88.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
BCR-ABL-IN-1
CAS:188260-50-6
BCR-ABL-IN-1 is a BCR-ABL tyrosine kinase inhibitor (pIC50: 6.46) and may be used in the …
Formula:
C23H21F4N5O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
459.44
Ref: TM-T10488
| 25mg | 1,410.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,329.00 € |
Estimated delivery in United States, on Wednesday 29 Jan 2025
Pivanex
CAS:122110-53-6
Pivanex, an oral HDAC inhibitor, targets metastasis, angiogenesis, reduces Bcr-Abl protein, and promotes apoptosis.
Formula:
C10H18O4
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
202.25
Ref: TM-T16545
| 1g | 224.00 € | ||
| 50mg | 40.00 € | ||
| 100mg | 72.00 € | ||
| 200mg | 95.00 € | ||
| 500mg | 157.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Wednesday 12 Feb 2025
BCR-ABL-IN-8
CAS:1808288-49-4
BCR-ABL-IN-8 (compound 26f) is a BCR-ABL inhibitor featuring a trimethoxy group [1].
Formula:
C30H33N7O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
571.63
Ref: TM-T82909
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Wednesday 12 Feb 2025
CHMFL-ABL-039
CAS:2304344-56-5
CHMFL-ABL-039 is a type II native ABL kinase and drug-resistant V299L mutant BCR-ABL inhibitor (IC50s: …
Formula:
C31H33F3N6O3
Purity:
98.63%
Color and Shape:
Solid
Molecular weight:
594.63
Ref: TM-T10799
| 1mg | Discontinued | Request information | |
| 2mg | Discontinued | Request information | |
| 5mg | Discontinued | Request information | |
| 10mg | Discontinued | Request information | |
| 25mg | Discontinued | Request information | |
| 50mg | Discontinued | Request information | |
| 100mg | Discontinued | Request information | |
| 1ml*10 (DMSO) | Discontinued | Request information |
CHMFL-ABL-121
CAS:2270879-07-5
CHMFL-ABL-121 is a highly potent inhibitor of type II ABL kinase (IC50s: 2 nM and …
Formula:
C30H31F3N6OS
Purity:
99.86%
Color and Shape:
Solid
Molecular weight:
580.67
Ref: TM-T10800
| 1mg | Discontinued | Request information | |
| 2mg | Discontinued | Request information | |
| 5mg | Discontinued | Request information | |
| 10mg | Discontinued | Request information | |
| 25mg | Discontinued | Request information | |
| 50mg | Discontinued | Request information | |
| 100mg | Discontinued | Request information | |
| 500mg | Discontinued | Request information | |
| 1ml*10 (DMSO) | Discontinued | Request information |
Bosutinib D8
Bosutinib D8 is a deuterium-labeled Bosutinib. Bosutinib (SKI-606) is a dual Src/Abl inhibitor (IC50s: 1.2 …
Formula:
C26H21D8Cl2N5O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
538.5
Ref: TM-T10583
| 100mg | Discontinued | Request information | |
| 500mg | Discontinued | Request information |
