EGFR
EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.
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PF-6274484
CAS:1035638-91-5
PF-6274484 is an EGFR inhibitor with Ki values of 0.14 and 0.18 nM for EGFR-L858R/T790M …
Formula:
C18H14ClFN4O2
Purity:
97.71%
Color and Shape:
Solid
Molecular weight:
372.78
Ref: TM-T22396
| 2mg | 40.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 510.00 € | ||
| 500mg | 1,112.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
WS3
CAS:1421227-52-2
WS3, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase …
Formula:
C28H30F3N7O3
Purity:
97.93% - 98.81%
Color and Shape:
Solid
Molecular weight:
569.58
Ref: TM-T2055
| 5mg | 52.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 122.00 € | ||
| 50mg | 209.00 € | ||
| 100mg | 386.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
CL-387785
CAS:194423-06-8
CL-387785 is an irreversible EGFR inhibitor with IC50 of 370 pM; overcomes T790M mutation resistance.
Formula:
C18H13BrN4O
Purity:
96.68% - 98.09%
Color and Shape:
Solid
Molecular weight:
381.23
Ref: TM-T2245
| 5mg | 38.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 102.00 € | ||
| 50mg | 163.00 € | ||
| 100mg | 255.00 € | ||
| 200mg | 359.00 € | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Tyrphostin B44, (+) enantiomer
CAS:133550-37-5
Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with …
Formula:
C18H16N2O3
Purity:
97.18%
Color and Shape:
Solid
Molecular weight:
308.33
Ref: TM-T22450
| 1mg | 50.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 102.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 266.00 € | ||
| 50mg | 364.00 € | ||
| 100mg | 524.00 € | ||
| 200mg | 712.00 € | ||
| 1mL*10mM (DMSO) | 113.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
lavendustin C
CAS:125697-93-0
lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine …
Formula:
C14H13NO5
Purity:
97.77%
Color and Shape:
Yellow To Tan Powder
Molecular weight:
275.26
Ref: TM-T4185
| 1mg | 43.00 € | ||
| 2mg | 57.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 158.00 € | ||
| 25mg | 341.00 € | ||
| 50mg | 507.00 € | ||
| 100mg | 730.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Canertinib
CAS:267243-28-7
Canertinib (CI-1033), a pan-erbB inhibitor, effectively targets esophageal cancer in vitro/vivo, altering metabolism and reducing …
Formula:
C24H25ClFN5O3
Purity:
100% - 99.18%
Color and Shape:
White Or Similar To White Crystalline Powder
Molecular weight:
485.94
Ref: TM-T6136
| 5mg | 37.00 € | ||
| 10mg | 54.00 € | ||
| 25mg | 69.00 € | ||
| 50mg | 86.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
AG-1557 hydrochloride (189290-58-2(free base))
AG-1557 hydrochloride is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: …
Formula:
C16H15ClIN3O2
Purity:
98.95%
Color and Shape:
Solid
Molecular weight:
443.66
Ref: TM-T4694
| 5mg | 35.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 90.00 € | ||
| 50mg | 149.00 € | ||
| 100mg | 260.00 € | ||
| 200mg | 381.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Tyrphostin AG 879
CAS:148741-30-4
Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher …
Formula:
C18H24N2OS
Purity:
99.05%
Color and Shape:
Solid
Molecular weight:
316.46
Ref: TM-T6712
| 5mg | 50.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 152.00 € | ||
| 50mg | 245.00 € | ||
| 100mg | 418.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Daphnetin
CAS:486-35-1
Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR …
Formula:
C9H6O4
Purity:
98.33% - 99.82%
Color and Shape:
Solid
Molecular weight:
178.14
Ref: TM-T2851
| 10mg | 50.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 164.00 € | ||
| 100mg | 239.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
NS309
CAS:18711-16-5
NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect …
Formula:
C8H4Cl2N2O2
Purity:
95.87%
Color and Shape:
Solid
Molecular weight:
231.04
Ref: TM-T4612
| 5mg | 57.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 119.00 € | ||
| 50mg | 214.00 € | ||
| 100mg | 318.00 € | ||
| 200mg | 465.00 € | ||
| 500mg | 734.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Cetuximab
CAS:205923-56-4
Cetuximab (C225) is a monoclonal antibody that is an inhibitor of human epidermal growth factor …
Formula:
C107H179N35O36S7
Purity:
100.00% - SDS-PAGE:98.4%；SEC-HPLC: 99.7%
Color and Shape:
Liquid
Molecular weight:
152 kDa
Ref: TM-T9905
| 1mg | 185.00 € | ||
| 2mg | 269.00 € | ||
| 5mg | 448.00 € | ||
| 10mg | 648.00 € | ||
| 25mg | 1,013.00 € | ||
| 50mg | 1,365.00 € | ||
| 100mg | 1,839.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Mubritinib
CAS:366017-09-6
Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.
Formula:
C25H23F3N4O2
Purity:
99.85% - 99.87%
Color and Shape:
Solid
Molecular weight:
468.47
Ref: TM-T6124
| 5mg | 189.00 € | ||
| 10mg | 287.00 € | ||
| 25mg | 544.00 € | ||
| 50mg | 772.00 € | ||
| 100mg | 1,270.00 € | ||
| 1mL*10mM (DMSO) | 270.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
AG1557
CAS:189290-58-2
AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: …
Formula:
C16H14IN3O2
Purity:
98.62% - 99.23%
Color and Shape:
Solid
Molecular weight:
407.21
Ref: TM-T2034
| 10mg | 48.00 € | ||
| 25mg | 81.00 € | ||
| 50mg | 118.00 € | ||
| 100mg | 182.00 € | ||
| 200mg | 273.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
(S)-Afatinib
CAS:439081-18-2
(S)-Afatinib (BIBW2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, …
Formula:
C24H25ClFN5O3
Purity:
100% - 99.96%
Color and Shape:
Off-White Solid
Molecular weight:
485.94
Ref: TM-T2303
| 1g | 64.00 € | ||
| 200mg | 36.00 € | ||
| 500mg | 50.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
E-4031
CAS:113559-13-0
E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by …
Formula:
C21H29Cl2N3O3S
Purity:
97.71% - 99.31%
Color and Shape:
Solid
Molecular weight:
474.44
Ref: TM-T7198
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 213.00 € | ||
| 50mg | 383.00 € | ||
| 100mg | 570.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Tyrphostin AG 528
CAS:133550-49-9
Tyrphostin AG 528 (Tyrphostin B66) is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 …
Formula:
C18H14N2O3
Purity:
99.74%
Color and Shape:
Solid
Molecular weight:
306.32
Ref: TM-T4528
| 5mg | 51.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 128.00 € | ||
| 50mg | 227.00 € | ||
| 100mg | 408.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
TAS0728
CAS:2088323-16-2
TAS0728 is a HER2 inhibitor, with antitumor activity
Formula:
C26H32N8O3
Purity:
97.78%
Color and Shape:
Solid
Molecular weight:
504.58
Ref: TM-T7819
| 1mg | 50.00 € | ||
| 5mg | 107.00 € | ||
| 10mg | 169.00 € | ||
| 25mg | 310.00 € | ||
| 50mg | 493.00 € | ||
| 100mg | 670.00 € | ||
| 200mg | 902.00 € | ||
| 1mL*10mM (DMSO) | 113.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
NRC-2694
CAS:936446-61-6
NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and …
Formula:
C24H26N4O3
Purity:
99.38%
Color and Shape:
Solid
Molecular weight:
418.49
Ref: TM-T16343
| 1mg | 82.00 € | ||
| 5mg | 155.00 € | ||
| 10mg | 241.00 € | ||
| 25mg | 409.00 € | ||
| 50mg | 542.00 € | ||
| 100mg | 780.00 € | ||
| 200mg | 1,034.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Theliatinib
CAS:1353644-70-8
Theliatinib: potent, selective EGFR inhibitor, anti-tumor; Ki=0.05 nM (EGFR), IC50=3 nM (EGFR), 22 nM (T790M/L858R).
Formula:
C25H26N6O2
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
442.51
Ref: TM-T7322
| 1mg | 52.00 € | ||
| 5mg | 142.00 € | ||
| 10mg | 222.00 € | ||
| 25mg | 368.00 € | ||
| 50mg | 553.00 € | ||
| 100mg | 757.00 € | ||
| 1mL*10mM (DMSO) | 156.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
20(S)-Ginsenoside Rg3
CAS:14197-60-5
20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via …
Formula:
C42H72O13
Purity:
100% - 99.53%
Color and Shape:
Solid
Molecular weight:
785.01
Ref: TM-T3402
| 5mg | 38.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 84.00 € | ||
| 50mg | 95.00 € | ||
| 100mg | 167.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
