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EGFR

EGFR

EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.

Found 572 products of "EGFR"

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  • Lavendustin C6
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    Lavendustin C6

    CAS:
    <p>Lavendustin C6 is a effective tyrosine kinase inhibitor.</p>
    Formula:C20H25NO5
    Color and Shape:Solid
    Molecular weight:359.42

    Ref: TM-T25644

  • PDZ1i
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    PDZ1i

    CAS:
    <p>PDZ1i: potent MDA-9/Syntenin inhibitor; crosses blood-brain barrier; targets GBM, FAK, EGFRvIII; lowers MMP secretion.</p>
    Formula:C28H26N8O4
    Color and Shape:Solid
    Molecular weight:538.56

    Ref: TM-T63797

  • Nazartinib mesylate
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    Nazartinib mesylate

    CAS:
    <p>Nazartinib mesylate is a novel, covalent mutant-selective inhibitor of EGFR (Ki and Kinact: 31 nM and 0.222/min on EGFR(L858R/790M) mutant).</p>
    Formula:C27H35ClN6O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:591.12

    Ref: TM-T11156L

  • Tyrphostin AG 112
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    Tyrphostin AG 112

    CAS:
    <p>Tyrphostin AG 112 is an inhibitor of EGFR phosphorylation.</p>
    Formula:C13H8N4O
    Purity:97.01%
    Color and Shape:Solid
    Molecular weight:236.23

    Ref: TM-T8534

  • DBPR112
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    DBPR112

    CAS:
    <p>DBPR112: oral furanopyrimidine EGFR inhibitor; IC50: 15 nM (EGFRWT), 48 nM (L858R/T790M); blocks ATP site, strong antitumor effects.</p>
    Formula:C32H31N5O3
    Purity:99.25%
    Color and Shape:Solid
    Molecular weight:533.62

    Ref: TM-T10965

  • Epertinib
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    Epertinib

    CAS:
    <p>Epertinib is a reversible and selective tyrosine kinase inhibitor of EGFR, HER2, and HER4 (IC50s: 1.48 nM, 7.15 nM, and 2.49 nM).</p>
    Formula:C30H27ClFN5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:560.02

    Ref: TM-T11213L

  • MS 39
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    MS 39

    CAS:
    <p>MS 39, a selective EGFR depressant, degrades mutant receptors in lung cancer lines without affecting wild-type. Effective in vitro and in mice.</p>
    Formula:C55H71ClFN9O7S
    Color and Shape:Solid
    Molecular weight:1056.72

    Ref: TM-T41156

  • RTC-5
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    RTC-5

    CAS:
    <p>RTC-5 (TRC-382) is a phenothiazine compound that has been specifically enhanced for its potent anti-cancer properties.</p>
    Formula:C24H22ClF3N2O3S
    Purity:98.14%
    Color and Shape:Solid
    Molecular weight:510.96

    Ref: TM-T12777

  • SDZ281-977
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    SDZ281-977

    CAS:
    <p>SDZ 281-977 is a derivative of Lavendustin A which is the EGF receptor tyrosine kinase inhibitor.</p>
    Formula:C18H20O5
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:316.35

    Ref: TM-T16866

  • EGFR-IN-2
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    EGFR-IN-2

    CAS:
    <p>EGFR-IN-2 is a oral and mutation-selective EGFR inhibito,NSCLC, with high selectivity for resistant single and double mutant T790M.</p>
    Formula:C26H33N9O3S
    Purity:98.52% - 99.79%
    Color and Shape:Solid
    Molecular weight:551.66

    Ref: TM-T11159

  • Gefitinib N-oxide
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    Gefitinib N-oxide

    CAS:
    <p>Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib N-oxide is the N-oxide derivative of Gefitinib.</p>
    Formula:C22H24ClFN4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:462.9

    Ref: TM-T11385

  • Nimotuzumab
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    Nimotuzumab

    CAS:
    <p>Nimotuzumab is a humanized therapeutic monoclonal antibody against epidermal growth factor receptor EGFR).</p>
    Purity:95.00% - 98.5% (SDS-PAGE); 96.4% (SEC-HPLC)
    Color and Shape:Liquid

    Ref: TM-T9923

  • EGFR-IN-5
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    EGFR-IN-5

    CAS:
    <p>EGFR-IN-5 inhibits EGFR &amp; mutants; IC50: EGFR 10.4nM, L858R 1.1nM, L858R/T790M 34nM, L858R/T790M/C797S 7.2nM.</p>
    Formula:C31H38FN9O
    Purity:98.17%
    Color and Shape:Solid
    Molecular weight:571.69

    Ref: TM-T11160

  • BKI-1369
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    BKI-1369

    CAS:
    <p>BKI-1369 is a bumped kinase inhibitor. BKI-1369 increases hERG-inhibitory activity (IC50:1.52 μM).</p>
    Formula:C23H27N7O
    Color and Shape:Solid
    Molecular weight:417.51

    Ref: TM-T10556

  • EGFR-IN-68
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    EGFR-IN-68

    CAS:
    <p>EGFR-IN-68, an EGFR inhibitor, has an IC50 of 0.33 μM and shows significant anticancer effects.</p>
    Formula:C24H22N2O
    Color and Shape:Solid
    Molecular weight:354.44

    Ref: TM-T61267

  • JBJ-04-125-02
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    JBJ-04-125-02

    CAS:
    <p>JBJ-04-125-02: Oral EGFR inhibitor, targets EGFRL858R/T790M with 0.26 nM IC50, halts cancer growth, anti-tumor.</p>
    Formula:C29H26FN5O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:543.61

    Ref: TM-T11714

  • EGFR mutant-IN-2
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    EGFR mutant-IN-2

    CAS:
    <p>EGFR mutant-IN-2 (Compound D51) is an inhibitor of EGFR mutants, specifically targeting EGFR L858R/T790M/C797S and EGFR del19/T790M/C797S mutants with IC50 values of 14 nM and 62 nM, respectively. This compound exhibits favorable pharmacokinetic (PK) parameters, safety properties, in vivo stability, and demonstrates antitumor activity [1].</p>
    Formula:C27H27F3N6O2S
    Color and Shape:Solid
    Molecular weight:556.6

    Ref: TM-T86344

  • Mutated EGFR-IN-2
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    Mutated EGFR-IN-2

    CAS:
    <p>Mutated EGFR-IN-2 is an inhibitor of mutant-selective EGFR.</p>
    Formula:C29H35FN8O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:562.64

    Ref: TM-T12130

  • GW 583340 dihydrochloride
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    GW 583340 dihydrochloride

    CAS:
    <p>GW 583340 dihydrochloride is a potent and orally available dual EGFR/ErbB2 inhibitor and inhibits 80% of tumor growth in a mouse xenograft mode.</p>
    Formula:C28H27Cl3FN5O3S2
    Purity:98.80%
    Color and Shape:Solid
    Molecular weight:671.03

    Ref: TM-T22827

  • EGFR-IN-64
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    EGFR-IN-64

    CAS:
    <p>EGFR-IN-64 inhibits EGFR with 0.33 μM IC50, showing promising anticancer properties.</p>
    Formula:C20H21N3O3
    Color and Shape:Solid
    Molecular weight:351.4

    Ref: TM-T61225