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EGFR

EGFR

EGFR (epidermal growth factor receptor) inhibitors are compounds that block the signaling of EGFR, a receptor that is often overexpressed in various cancers and plays a critical role in angiogenesis. EGFR inhibitors are used to prevent tumor growth and metastasis by disrupting the pathways that promote blood vessel formation in tumors. These inhibitors are widely used in cancer research and therapy. At CymitQuimica, we offer a diverse selection of high-quality EGFR inhibitors to support your research in oncology and angiogenesis.

Found 572 products of "EGFR"

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  • JNJ28871063 hydrochloride
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    JNJ28871063 hydrochloride

    CAS:
    <p>ErbB receptor family inhibitor</p>
    Formula:C24H28Cl2N6O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:519.42

    Ref: TM-T22881

  • Mutated EGFR-IN-3
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    Mutated EGFR-IN-3

    CAS:
    <p>Mutated EGFR-IN-3: ATP-competitive, selective dibenzodiazepinone inhibitor for EGFR mutations, IC50 12-13 nM.</p>
    Formula:C31H29FN4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:508.59

    Ref: TM-T12131

  • EMI48
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    EMI48

    CAS:
    <p>EMI48, a derivative of EMI1, exhibits increased efficacy against mutant EGFR compared to EMI1. It specifically inhibits EGFR triple mutants [1].</p>
    Formula:C21H20N2O3
    Color and Shape:Solid
    Molecular weight:348.4

    Ref: TM-T61179

  • EGFR-IN-39
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    EGFR-IN-39

    CAS:
    <p>EGFR-IN-39, an acrylamide, is a potent EGFR inhibitor and antitumor agent targeting NSCLC with low toxicity. See WO2021185348A1 for details.</p>
    Formula:C24H25ClN6O3
    Color and Shape:Solid
    Molecular weight:480.95

    Ref: TM-T63178

  • Selatinib
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    Selatinib

    CAS:
    <p>Selatinib is an orally active and potent dual inhibitor of EGFR and ErbB2 with anticancer activity that inhibits the growth of NCI-N87 tumor cells.</p>
    Formula:C29H26ClFN4O3S
    Purity:98.00%
    Color and Shape:Solid
    Molecular weight:565.06

    Ref: TM-T34602

  • EMI56
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    EMI56

    CAS:
    <p>EMI56, a derivative of EMI1, exhibits enhanced potency against mutant EGFR compared to EMI1. Additionally, EMI56 effectively inhibits EGFR triple mutants[1].</p>
    Formula:C21H20N2O3
    Color and Shape:Solid
    Molecular weight:348.4

    Ref: TM-T35913

  • EGFR-IN-55
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    EGFR-IN-55

    CAS:
    <p>"EGFR-IN-55 targets EGFRWT (70 nM IC50) &amp; EGFRL858R/T790M (3.9 nM IC50), halts NCI-H1975 cell cycle in G0/G1, showing anticancer properties."</p>
    Formula:C25H25Cl2N7O2
    Color and Shape:Solid
    Molecular weight:526.42

    Ref: TM-T63693

  • EGFR-IN-49
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    EGFR-IN-49

    CAS:
    <p>EGFR-IN-49 selectively inhibits EGFR mutations T790M (IC50: 65 nM) &amp; T790M/L858R (IC50: 13.6 nM), triggering apoptosis dose-dependently.</p>
    Formula:C22H15N5O2S
    Color and Shape:Solid
    Molecular weight:413.45

    Ref: TM-T62113

  • EGFR-IN-31
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    EGFR-IN-31

    CAS:
    <p>EGFR-IN-31: Potent EGFR inhibitor, targets mutations &amp; overexpression in NSCLC; potential cancer research compound. (WO2021185298A1, 2)</p>
    Formula:C32H36FN7O2
    Color and Shape:Solid
    Molecular weight:569.67

    Ref: TM-T64030

  • EGFR/HER2-IN-3
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    EGFR/HER2-IN-3

    CAS:
    <p>EGFR/HER2-IN-3 (Compound ZINC21942954) is a dual EGFR and HER2 inhibitor.</p>
    Formula:C26H23N5O3
    Color and Shape:Solid
    Molecular weight:453.49

    Ref: TM-T62777

  • Tyrphostin 51
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    Tyrphostin 51

    CAS:
    <p>Tyrphostin 51 is an effective inhibitor of EGFR kinase.</p>
    Formula:C13H8N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:268.23

    Ref: TM-T24909

  • EGFR-IN-25
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    EGFR-IN-25

    CAS:
    <p>EGFR-IN-25, an efficacious EGFR inhibitor, demonstrates IC50 values of 9 nM for BaF3 cells (EGFR DEL19/T790M/C797S) and 60 nM for A431 cells (WT), respectively.</p>
    Formula:C34H43N9O2
    Color and Shape:Solid
    Molecular weight:609.76

    Ref: TM-T73101

  • MS 154N
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    MS 154N

    CAS:
    <p>MS 154N is a negative control for MS 154, binds WT/L858R EGFR tightly (Kd 3-4.3nM), doesn't trigger mutant EGFR degradation.</p>
    Formula:C47H56ClFN8O8
    Color and Shape:Solid
    Molecular weight:915.45

    Ref: TM-T41157

  • JBJ-09-063 hydrochloride
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    JBJ-09-063 hydrochloride

    <p>JBJ-09-063 hydrochloride: targeted EGFR inhibitor, effective for various mutations and TKI-resistant lung cancer models.</p>
    Formula:C31H30ClFN4O3S
    Color and Shape:Solid
    Molecular weight:593.11

    Ref: TM-T72237

  • PD 173955-Analog1
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    PD 173955-Analog1

    CAS:
    <p>PD 173955-Analog1 is a potent c-Src inhibitor known to have activity against a variety of cancers including colon, lung, head and neck carcinoma.</p>
    Formula:C21H14Cl2N4O3
    Color and Shape:Solid
    Molecular weight:441.27

    Ref: TM-T71912

  • EGA
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    EGA

    CAS:
    <p>EGA blocks the entry of a variety of other acid-dependent bacterial toxins and viruses into mammalian cells and can be used to treat infectious diseases.</p>
    Formula:C16H16BrN3O
    Purity:98% - 99.6%
    Color and Shape:Solid
    Molecular weight:346.22

    Ref: TM-T25365

  • DS21360717
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    DS21360717

    CAS:
    <p>DS21360717 is an effective oral tyrosine kinase inhibitor with anticancer activity and IC50 of 0.49 nM.</p>
    Formula:C21H23N7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:389.45

    Ref: TM-T11104

  • EGFR/HER2-IN-2
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    EGFR/HER2-IN-2

    CAS:
    <p>EGFR/HER2-IN-2 (Compound ZINC35560729) is a dual EGFR and HER2 inhibitor that acts on both EGFR (IC50: 5.02 μM) and HER2 (IC50: 0.83 μM).</p>
    Formula:C26H23N5O3
    Color and Shape:Solid
    Molecular weight:453.49

    Ref: TM-T62776

  • UNC-CA359
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    UNC-CA359

    CAS:
    <p>UNC-CA359: potent EGFR inhibitor, IC50=18 nM, strong anti-tumor effect, promising for chordoma.</p>
    Formula:C18H14ClN3O2
    Color and Shape:Solid
    Molecular weight:339.78

    Ref: TM-T61077

  • CAY10717
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    CAY10717

    CAS:
    <p>CAY10717 inhibits 34/104 kinases at 100 nM, targets EGFR/ABL/B-Raf mutations, kills various cancer cells, and blocks HUVEC growth.</p>
    Formula:C29H25F3N6O3
    Color and Shape:Solid
    Molecular weight:562.54

    Ref: TM-T36193