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BTK

BTK

BTK (Bruton's tyrosine kinase) inhibitors are compounds that specifically target and inhibit BTK, a crucial enzyme involved in B-cell receptor signaling and the regulation of angiogenesis. BTK plays a significant role in the proliferation and survival of cancer cells, particularly in hematological malignancies. By inhibiting BTK, these compounds can disrupt angiogenesis and tumor growth, making them valuable in cancer therapy. At CymitQuimica, we offer a range of high-quality BTK inhibitors to support your research in oncology, immunology, and angiogenesis.

Found 145 products of "BTK"

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  • BMS-986142

    CAS:
    <p>BMS-986142 is a potent and highly selective reversible BTK inhibitor (IC50: 0.5 nM).</p>
    Formula:C32H30F2N4O4
    Purity:98.7% - 99.76%
    Color and Shape:Solid
    Molecular weight:572.6
  • Acalabrutinib

    CAS:
    <p>Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity.</p>
    Formula:C26H23N7O2
    Purity:98.94% - 99.64%
    Color and Shape:Solid
    Molecular weight:465.51
  • (Rac)-IBT6A

    CAS:
    <p>(Rac)-IBT6A is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.</p>
    Formula:C22H22N6O
    Purity:99.24%
    Color and Shape:Solid
    Molecular weight:386.45
  • TL-895

    CAS:
    <p>TL-895 is a potent, selective ATP-competitive BTK inhibitor (IC50 = 1.5 nM, Ki = 11.9 nM).</p>
    Formula:C25H26FN5O2
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:447.5
  • Spebrutinib

    CAS:
    <p>Spebrutinib (LMK-435) is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic</p>
    Formula:C22H22FN5O3
    Purity:97.02% - >99.99%
    Color and Shape:Solid
    Molecular weight:423.44
  • ONO-4059 analog

    CAS:
    <p>ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.</p>
    Formula:C25H24N6O3
    Purity:99.25%
    Color and Shape:Solid
    Molecular weight:456.5
  • RN486

    CAS:
    <p>RN486 is an effective and specific BTK inhibitor (IC50: 4 nM).</p>
    Formula:C35H35FN6O3
    Purity:99.38%
    Color and Shape:Solid
    Molecular weight:606.69
  • Branebrutinib

    CAS:
    <p>Branebrutinib (BMS986195) is a potent, covalent inhibitor of Bruton's tyrosine kinase (BTK), &gt;5,000-fold selective over all kinases outside of the Tec family.</p>
    Formula:C20H23FN4O2
    Purity:95.86% - 99.31%
    Color and Shape:Solid
    Molecular weight:370.42
  • Larotinib mesylate hydrate

    CAS:
    <p>Larotinib mesylate hydrate is a potent, broad-spectrum, and orally active tyrosine kinase inhibitor (TKI), primarily targeting EGFR with an IC50 value of 0.6 nM</p>
    Formula:C26H36ClFN4O11S2
    Color and Shape:Solid
    Molecular weight:699.17
  • CNX-774

    CAS:
    <p>CNX-774 is a highly specific, irreversible, and orally active BTK inhibitor (IC50&lt;1 nM).</p>
    Formula:C26H22FN7O3
    Purity:97.35% - 99.11%
    Color and Shape:Solid
    Molecular weight:499.5
  • CGI-1746

    CAS:
    <p>CGI1746 is a potent and highly selective small-molecule Btk inhibitor with IC50 of 1.9 nM.</p>
    Formula:C34H37N5O4
    Purity:97.69% - 97.88%
    Color and Shape:Solid
    Molecular weight:579.69
  • Avitinib

    CAS:
    <p>Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,</p>
    Formula:C26H26FN7O2
    Purity:99.81% - >99.99%
    Color and Shape:Solid
    Molecular weight:487.53
  • BTK IN-1

    CAS:
    <p>BTK IN-1 (SNS062 analog) (SNS062 analog) is an effective BTK inhibitor (IC50: &lt;100 nM).</p>
    Formula:C19H21ClN6O
    Purity:97.38%
    Color and Shape:Solid
    Molecular weight:384.86
  • BTK Protein, Human, Recombinant (His)


    <p>Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling.</p>
    Purity:90%
    Color and Shape:Lyophilized Powder
    Molecular weight:78.3 kDa (predicted)
  • Ibrutinib-d5

    CAS:
    <p>Ibrutinib D5 is a deuterium-labeled Ibrutinib. Ibrutinib is an irreversible Btk inhibitor.</p>
    Formula:C25H24N6O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:445.53
  • JAK3/BTK-IN-5

    CAS:
    <p>JAK3/BTK-IN-5 is a potent dual inhibitor targeting JAK3 and BTK with synergistic effects, valuable for related autoimmune disease research.</p>
    Formula:C19H22ClN7O2
    Color and Shape:Solid
    Molecular weight:415.88
  • BLK-IN-2

    CAS:
    <p>BLK-IN-2为一种高效、选择性且不可逆的B-淋巴酪氨酸激酶(BLK)抑制剂,具有5.9 nM的IC50值。该化合物亦能抑制BTK,其IC50值为202.0 nM。BLK-IN-2在多种淋巴瘤细胞中展现出显著的抗增殖作用。</p>
    Formula:C39H41N9O3
    Color and Shape:Solid
    Molecular weight:683.8
  • EGFR-IN-40

    CAS:
    <p>EGFR-IN-40 (compound 3z) is a potent inhibitor of BTK (IC50: 1.2 nM), EGFR (IC50: 5.3 nM) and ITK (IC50: 46.1 nM).</p>
    Formula:C23H20N6O3
    Color and Shape:Solid
    Molecular weight:428.44
  • GDC-0834 Racemate

    CAS:
    <p>GDC-0834 Racemate is the racemate form of GDC-0834, which is an effective and selective BTK inhibitor</p>
    Formula:C33H36N6O3S
    Color and Shape:Solid
    Molecular weight:596.74
  • BTK inhibitor 10

    CAS:
    <p>BTK inhibitor 10, an oral drug from patent WO2018145525, may treat rheumatoid arthritis.</p>
    Formula:C25H23N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:441.48