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BTK

BTK

BTK (Bruton's tyrosine kinase) inhibitors are compounds that specifically target and inhibit BTK, a crucial enzyme involved in B-cell receptor signaling and the regulation of angiogenesis. BTK plays a significant role in the proliferation and survival of cancer cells, particularly in hematological malignancies. By inhibiting BTK, these compounds can disrupt angiogenesis and tumor growth, making them valuable in cancer therapy. At CymitQuimica, we offer a range of high-quality BTK inhibitors to support your research in oncology, immunology, and angiogenesis.

Found 145 products of "BTK"

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  • BIIB091
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    BIIB091

    CAS:
    <p>BIIB091 is a highly selective, reversible BTK inhibitor for treating autoimmune diseases.</p>
    Formula:C28H34N10O2
    Color and Shape:Solid
    Molecular weight:542.648

    Ref: TM-T39761

  • CymitQuimica logo
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    Anti-BTK Antibody (3G585)

    <p>Anti-BTK Antibody (3G585) is an antibody targeting BTK. Anti-BTK Antibody (3G585) can be used in ELISA, IHC.</p>
    Color and Shape:Odour Liquid

    Ref: TM-TMAH-00122

  • IBT6A hydrochloride
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    IBT6A hydrochloride

    CAS:
    <p>IBT6A hydrochloride: Ibrutinib impurity, Btk inhibitor IC50: 0.5 nM, used in dimer/adduct synthesis.</p>
    Formula:C22H23ClN6O
    Color and Shape:Solid
    Molecular weight:422.91

    Ref: TM-T10625L2

  • Elsubrutinib
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    Elsubrutinib

    CAS:
    <p>Elsubrutinib (ABBV-105) is a highly active, potent, and selective orally-administered inhibitor of Bruton's tyrosine kinase (BTK). It irreversibly inhibits the catalytic domain of BTK with an IC50 value of 0.18 μM. Elsubrutinib holds potential for the advancement of research on inflammatory diseases.</p>
    Formula:C17H19N3O2
    Color and Shape:Solid
    Molecular weight:297.358

    Ref: TM-T39130

  • Poseltinib
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    Poseltinib

    CAS:
    <p>Poseltinib is an oral, irreversible BTK inhibitor (IC50 1.95 nM) with higher selectivity over BMX, TEC, and TXK, blocking BCR, FcR, and TLR signaling.</p>
    Formula:C26H26N6O3
    Color and Shape:Solid
    Molecular weight:470.52

    Ref: TM-T4413

  • GDC-0834
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    GDC-0834

    CAS:
    <p>GDC-0834 inhibits BTK with an in vitro IC50 of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivo IC50 of 1.1 and 5.6 μM in mouse and</p>
    Formula:C33H36N6O3S
    Color and Shape:Solid
    Molecular weight:596.74

    Ref: TM-T11379

  • NX-5948
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    NX-5948

    CAS:
    <p>NX-5948 (BTK-IN-24) is a PROTAC-type BTK degrader with anti-inflammatory and anticancer activities, inhibiting B cell activation.</p>
    Formula:C42H54N12O5
    Purity:98.29%
    Color and Shape:Solid
    Molecular weight:806.96

    Ref: TM-T75124

  • N-piperidine Ibrutinib hydrochloride
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    N-piperidine Ibrutinib hydrochloride

    CAS:
    <p>N-piperidine Ibrutinib hydrochloride is a BTK inhibitor that inhibits WT BTK and C481S BTK , which inhibits the growth and proliferation of cancer cells.</p>
    Formula:C22H23ClN6O
    Purity:98.83%
    Color and Shape:Solid
    Molecular weight:422.91

    Ref: TM-T12152

  • BMS-986142
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    BMS-986142

    CAS:
    <p>BMS-986142 is a potent and highly selective reversible BTK inhibitor (IC50: 0.5 nM).</p>
    Formula:C32H30F2N4O4
    Purity:98.7% - 99.76%
    Color and Shape:Solid
    Molecular weight:572.6

    Ref: TM-T5138

  • TL-895
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    TL-895

    CAS:
    <p>TL-895 is a potent, selective ATP-competitive BTK inhibitor (IC50 = 1.5 nM, Ki = 11.9 nM).</p>
    Formula:C25H26FN5O2
    Purity:99.96%
    Color and Shape:Solid
    Molecular weight:447.5

    Ref: TM-T9705

  • N-piperidine Ibrutinib
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    N-piperidine Ibrutinib

    CAS:
    <p>N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively.</p>
    Formula:C22H22N6O
    Purity:96.65%
    Color and Shape:Solid
    Molecular weight:386.45

    Ref: TM-T9408

  • CGI-1746
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    CGI-1746

    CAS:
    <p>CGI1746 is a potent and highly selective small-molecule Btk inhibitor with IC50 of 1.9 nM.</p>
    Formula:C34H37N5O4
    Purity:97.69% - 97.88%
    Color and Shape:Solid
    Molecular weight:579.69

    Ref: TM-T2472

  • Ibrutinib deacryloylpiperidine
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    Ibrutinib deacryloylpiperidine

    CAS:
    <p>Ibrutinib deacryloylpiperidine (IBT4A) is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.</p>
    Formula:C17H13N5O
    Purity:99.47%
    Color and Shape:Solid
    Molecular weight:303.32

    Ref: TM-T8636

  • CHMFL-BMX-078
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    CHMFL-BMX-078

    CAS:
    <p>CHMFL-BMX-078 is a highly potent and selective type II irreversible BMX kinase inhibitor with an IC50 of 11 nM.</p>
    Formula:C33H35N7O6
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:625.67

    Ref: TM-T4268

  • RN486
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    RN486

    CAS:
    <p>RN486 is an effective and specific BTK inhibitor (IC50: 4 nM).</p>
    Formula:C35H35FN6O3
    Purity:99.38%
    Color and Shape:Solid
    Molecular weight:606.69

    Ref: TM-T1976

  • CNX-774
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    CNX-774

    CAS:
    <p>CNX-774 is a highly specific, irreversible, and orally active BTK inhibitor (IC50&lt;1 nM).</p>
    Formula:C26H22FN7O3
    Purity:97.35% - 99.11%
    Color and Shape:Solid
    Molecular weight:499.5

    Ref: TM-T2302

  • Larotinib mesylate hydrate
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    Larotinib mesylate hydrate

    CAS:
    <p>Larotinib mesylate hydrate is a potent, broad-spectrum, and orally active tyrosine kinase inhibitor (TKI), primarily targeting EGFR with an IC50 value of 0.6 nM</p>
    Formula:C26H36ClFN4O11S2
    Color and Shape:Solid
    Molecular weight:699.17

    Ref: TM-T72207

  • Avitinib
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    Avitinib

    CAS:
    <p>Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,</p>
    Formula:C26H26FN7O2
    Purity:99.81% - >99.99%
    Color and Shape:Solid
    Molecular weight:487.53

    Ref: TM-T3024

  • Spebrutinib
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    Spebrutinib

    CAS:
    <p>Spebrutinib (LMK-435) is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic</p>
    Formula:C22H22FN5O3
    Purity:97.02% - >99.99%
    Color and Shape:Solid
    Molecular weight:423.44

    Ref: TM-T2603

  • (Z)-LFM-A13
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    (Z)-LFM-A13

    CAS:
    <p>(Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.</p>
    Formula:C11H8Br2N2O2
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:360

    Ref: TM-T6217