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Syk

Syk

Syk (spleen tyrosine kinase) inhibitors are compounds that target Syk, a kinase involved in immune cell signaling and the regulation of angiogenesis. Syk plays a role in the inflammatory responses that can contribute to tumor angiogenesis. Inhibiting Syk can reduce inflammation-induced blood vessel formation in tumors, making these inhibitors valuable in cancer therapy and inflammation research. At CymitQuimica, we offer a diverse range of high-quality Syk inhibitors to support your research in immunology, oncology, and angiogenesis.

Found 38 products of "Syk"

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  • Piceatannol

    CAS:
    Formula:C14H12O4
    Purity:>98.0%(HPLC)
    Color and Shape:White to Light yellow to Light red powder to crystal
    Molecular weight:244.25

    Ref: 3B-P1928

    1g
    478.00€
    100mg
    77.00€
  • Gusacitinib

    CAS:
    <p>Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).</p>
    Formula:C24H28N8O2
    Purity:98.06% - 99.94%
    Color and Shape:Solid
    Molecular weight:460.53
  • Adrenalone hydrochloride

    CAS:
    <p>Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.</p>
    Formula:C9H11NO3·HCl
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:217.65
  • 1,3-Benzodioxole, 5-(2-nitroethenyl)-

    CAS:
    Formula:C9H7NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:193.1562

    Ref: IN-DA001KYU

    1g
    44.00€
    5g
    66.00€
    25g
    166.00€
    100g
    352.00€
    250mg
    28.00€
  • Piceatannol

    CAS:
    <p>Piceatannol (Astringenin) is a synthetic anti-inflammatory that blocks p56lck, syk kinases, and NF-κB, made from resveratrol.</p>
    Formula:C14H12O4
    Purity:98.66% - 99.73%
    Color and Shape:Light Tan To Yellow Powder
    Molecular weight:244.24
  • Lanraplenib

    CAS:
    <p>Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.</p>
    Formula:C23H25N9O
    Purity:98.35%
    Color and Shape:Solid
    Molecular weight:443.5
  • 1,2-Benzenediol, 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]-

    CAS:
    Formula:C14H12O4
    Purity:97%
    Color and Shape:Solid
    Molecular weight:244.2427

    Ref: IN-DA0002ZH

    1g
    26.00€
    5g
    68.00€
    10g
    105.00€
    25g
    198.00€
    100mg
    25.00€
    250mg
    29.00€
  • Tyrosine Kinase Inhibitor Library


    <p>A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related</p>
    Color and Shape:Odour Solid
  • Syk Kinase Peptide Substrate, Biotin labeled


    <p>The compound, Biotin-labeled Syk Kinase Peptide Substrate, is a peptide substrate of Syk kinase that is labeled with biotin.</p>
    Formula:C76H108N18O24S1
    Color and Shape:Solid
    Molecular weight:1689.9
  • Cevidoplenib dimesylate

    CAS:
    <p>Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.</p>
    Formula:C27H35N7O9S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:665.74
  • Syk-IN-7


    <p>Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1].</p>
    Formula:C26H31N9O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:533.58
  • Lanraplenib succinate

    CAS:
    <p>Lanraplenib succinate is an oral SYK inhibitor (IC50=9.5 nM) that doesn't extend BT, targeting GPVI in platelets for inflammation treatment.</p>
    Formula:C58H68N18O14
    Color and Shape:Solid
    Molecular weight:1241.294
  • MNS

    CAS:
    Formula:C9H7NO4
    Purity:>98.0%(GC)
    Color and Shape:Light yellow to Yellow to Green powder to crystal
    Molecular weight:193.16

    Ref: 3B-M3390

    100mg
    58.00€
    500mg
    174.00€
  • BAY 61-3606 dihydrochloride

    CAS:
    <p>BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).</p>
    Formula:C20H18N6O3·2HCl
    Purity:99.46%
    Color and Shape:Solid
    Molecular weight:463.32
  • Fostamatinib

    CAS:
    <p>Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.</p>
    Formula:C23H26FN6O9P
    Purity:93.08% - 99.38%
    Color and Shape:Solid
    Molecular weight:580.46
  • TAK-659 hydrochloride

    CAS:
    <p>TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.</p>
    Formula:C17H22ClFN6O
    Purity:99.28% - 99.82%
    Color and Shape:Solid
    Molecular weight:380.85
  • Flavanomarein

    CAS:
    <p>Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.</p>
    Formula:C21H22O11
    Purity:98.63% - 99.54%
    Color and Shape:Solid
    Molecular weight:450.39
  • PRT-060318

    CAS:
    <p>PRT-060318 (P142-76) is a novel selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment.</p>
    Formula:C18H24N6O
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:340.42
  • PRT062607 hydrochloride

    CAS:
    <p>PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk. PRT062607 displays at least 80-fold selectivity for Syk over other kinases.</p>
    Formula:C19H23N9O·HCl
    Purity:97.7% - 99.81%
    Color and Shape:Solid
    Molecular weight:429.91
  • BAY 61-3606

    CAS:
    <p>BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting</p>
    Formula:C20H18N6O3
    Purity:98.72%
    Color and Shape:Solid
    Molecular weight:390.4
  • Cerdulatinib

    CAS:
    <p>Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.</p>
    Formula:C20H27N7O3S
    Purity:98.74% - 99.49%
    Color and Shape:Solid
    Molecular weight:445.54
  • MNS

    CAS:
    <p>MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.</p>
    Formula:C9H7NO4
    Purity:98.53%
    Color and Shape:Yellow Powder
    Molecular weight:193.16
  • R112

    CAS:
    <p>R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.</p>
    Formula:C16H13FN4O2
    Purity:99.27% - 99.84%
    Color and Shape:Solid
    Molecular weight:312.3
  • Fostamatinib Disodium

    CAS:
    <p>Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.</p>
    Formula:C23H24FN6O9P·2Na
    Purity:96.13% - 99.09%
    Color and Shape:Solid
    Molecular weight:624.42
  • Entospletinib

    CAS:
    <p>Entospletinib (GS-9973) is a Syk inhibitor (IC50=7.7 nM) with selective, oral activity. High-Quality, Low-Cost!</p>
    Formula:C23H21N7O
    Purity:98.54% - 99.51%
    Color and Shape:Solid
    Molecular weight:411.46
  • R406

    CAS:
    <p>R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.</p>
    Formula:C22H23FN6O5·C6H6O3S
    Purity:97.67% - 98.82%
    Color and Shape:Solid
    Molecular weight:628.63
  • R406 free base

    CAS:
    <p>R406 free base (R406 (free base)) is a potent Syk inhibitor.</p>
    Formula:C22H23FN6O5
    Purity:97.64% - 99.11%
    Color and Shape:Solid
    Molecular weight:470.45
  • Cerdulatinib hydrochloride

    CAS:
    <p>Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 &lt; 200 nM.</p>
    Formula:C20H28ClN7O3S
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:482
  • Syk Inhibitor II

    CAS:
    <p>Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).</p>
    Formula:C14H15F3N6O
    Purity:97.63%
    Color and Shape:Solid
    Molecular weight:340.3
  • ER-27319

    CAS:
    <p>ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosine</p>
    Formula:C20H22N2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:370.4
  • Sovleplenib

    CAS:
    <p>Sovleplenib (HMPL-523), oral SYK inhibitor, IC50 25 nM, targets tumors &amp; ITP studies.</p>
    Formula:C24H30N6O3S
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:482.6
  • Syk-IN-3

    CAS:
    <p>Syk-IN-3 is a Syk inhibitor with potential anti-inflammatory and anticancer activity and can be used to study immune dysregulation.</p>
    Formula:C24H28N4O3S
    Purity:97.29% - >99.99%
    Color and Shape:Solid
    Molecular weight:452.57
  • RO9021

    CAS:
    <p>RO9021 is an orally bioavailable, novel ATP-competitive SYK inhibitor (average IC50: 5.6 nM).</p>
    Formula:C18H25N7O
    Purity:97.19%
    Color and Shape:Solid
    Molecular weight:355.44
  • TC-S 7003

    CAS:
    <p>TC-S 7003 (Lck Inhibitor) is a Lck inhibitor with anti-inflammatory activity that inhibits T-cell proliferation and can be used to study arthritis.</p>
    Formula:C31H30N8O
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:530.62
  • Lanraplenib monosuccinate

    CAS:
    <p>Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.</p>
    Formula:C27H31N9O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:561.59
  • OXSI-2

    CAS:
    <p>OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.</p>
    Formula:C18H15N3O3S
    Purity:98%
    Color and Shape:Dark Orange Solid
    Molecular weight:353.39
  • MK-8457

    CAS:
    <p>MK-8457 is a dual inhibitor of SYK and ZAP70, valuable for rheumatoid arthritis research [1].</p>
    Formula:C24H25F3N4O3S
    Color and Shape:Solid
    Molecular weight:506.54
  • Syk-IN-8

    CAS:
    <p>Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells.</p>
    Formula:C23H26N10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:442.52

    Ref: TM-T79443

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    50mg
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