TNF
TNF (Tumor Necrosis Factor) inhibitors are compounds that block the activity of TNF, a cytokine involved in inflammation and the regulation of apoptosis. TNF can induce apoptosis in some cell types while promoting survival and inflammation in others. Inhibiting TNF is crucial in the treatment of autoimmune diseases, chronic inflammatory conditions, and certain cancers. TNF inhibitors help to modulate the immune response and reduce tissue damage caused by excessive inflammation. At CymitQuimica, we provide a diverse range of high-quality TNF inhibitors to support your research in immunology, inflammation, and apoptosis.
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Golimumab
CAS:476181-74-5
Golimumab (CNTO-148), an anti-TNFα IgG1κ monoclonal antibody with anti-inflammatory and anti-cancer activity, can be used …
Color and Shape:
Liquid
Molecular weight:
146.93 kDa
Ref: TM-T76711
| 1mg | 226.00 € | ||
| 5mg | 522.00 € | ||
| 10mg | 727.00 € | ||
| 25mg | 1,105.00 € | ||
| 50mg | 1,476.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Kdo2-Lipid A ammonium
CAS:1246298-62-3
Kdo2-Lipid A ammonium (KLA) is a selective and potent TLR4 agonist, a lipopolysaccharide.Kdo2-Lipid A ammonium …
Formula:
C110H214N6O39P2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
2306.84
Ref: TM-T38635
| 1mg | 1,169.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea
CAS:2379727-88-3
1-(4-Chloro-3-(trifluoromethyl)phenyl)urea derivative induces TNF-α secretion.
Formula:
C24H21ClF3N5O
Purity:
97.90% - 98.61%
Color and Shape:
Soild
Molecular weight:
487.9
Ref: TM-T60124
| 1mg | 113.00 € | ||
| 2mg | 169.00 € | ||
| 5mg | 249.00 € | ||
| 10mg | 366.00 € | ||
| 25mg | 618.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Belimumab
CAS:356547-88-1
Belimumab, a human IgG1λ monoclonal antibody, blocks BAFF, treating lupus and related fatigue.
Purity:
SDS-PAGE:98.4%;SEC-HPLC:98.4%
Color and Shape:
Liquid
Molecular weight:
144.07 kDa
Ref: TM-T76957
| 1mg | 48.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 17 Dec 2024
HS-243
CAS:848249-10-5
HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. …
Formula:
C17H16N4O3
Purity:
97.34%
Color and Shape:
Liquid
Molecular weight:
324.33
Ref: TM-T60012
| 1mg | 53.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 377.00 € | ||
| 50mg | 559.00 € | ||
| 100mg | 800.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Ozoralizumab
CAS:1167985-17-2
Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.
Purity:
SDS-PAGE:> 95%;SEC-HPLC:95.6%
Color and Shape:
Liquid
Molecular weight:
38.44 kDa
Ref: TM-T77126
| 1mg | 306.00 € | ||
| 5mg | 782.00 € | ||
| 10mg | 1,184.00 € | ||
| 25mg | 1,762.00 € | ||
| 50mg | 2,378.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Siegeskaurolic acid
CAS:52645-97-3
Siegeskaurolic acid reduces inflammation and pain by blocking iNOS and COX-2 in macrophages via NF-kappaB …
Formula:
C20H32O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
320.47
Ref: TM-TN5019
| 1mg | 614.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
EJMC-1
CAS:397281-20-8
EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can …
Formula:
C17H11ClN2O4S
Purity:
97.69%
Color and Shape:
Liquid
Molecular weight:
374.8
Ref: TM-T60054
| 1mg | 142.00 € | ||
| 2mg | 204.00 € | ||
| 5mg | 344.00 € | ||
| 10mg | 490.00 € | ||
| 25mg | 713.00 € | ||
| 50mg | 975.00 € | ||
| 100mg | 1,319.00 € | ||
| 500mg | 2,646.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Conatumumab
CAS:896731-82-1
Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM …
Purity:
> 95% - > 95%
Color and Shape:
Liquid
Molecular weight:
145 kDa (average)
Ref: TM-T76787
| 1mg | 353.00 € | ||
| 5mg | 891.00 € | ||
| 10mg | 1,427.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Varlilumab
CAS:1393344-72-3
Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and …
Purity:
SDS-PAGE:95% SEC-HPLC:98.65%
Color and Shape:
Liquid
Molecular weight:
146 kDa
Ref: TM-T76706
| 1mg | 581.00 € | ||
| 5mg | 1,981.00 € | ||
| 10mg | 2,666.00 € | ||
| 25mg | 3,943.00 € | ||
| 50mg | 5,317.00 € | ||
| 100mg | 7,200.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
Teneliximab
CAS:299423-37-3
Teneliximab (BMS 224819) is a chimeric monoclonal antibody that blocks CD40-CD40L interactions.Cost-effective and quality-assured.
Purity:
95.00% - 99.19% (SEC-HPLC)
Color and Shape:
Liquid
Molecular weight:
146.06 kDa
Ref: TM-T76830
| 1mg | 158.00 € | ||
| 5mg | 401.00 € | ||
| 10mg | 621.00 € | ||
| 25mg | 925.00 € | ||
| 50mg | 1,284.00 € | ||
| 100mg | 1,733.00 € | ||
| 200mg | 2,333.00 € |
Estimated delivery in United States, on Tuesday 17 Dec 2024
TNF α Protein, Ferret, Recombinant (His)
TNF alpha Protein, Ferret, Recombinant (His) is expressed in E.
Color and Shape:
Liquid
Molecular weight:
18.88 kDa (predicted) same as Tris-Bis PAGE result.
Ref: TM-TMPK-00583
| 1mg | 3,085.00 € | ||
| 100µg | 488.00 € | ||
| 500µg | 1,851.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
TNF α Protein, Human, Recombinant (His & Avi), Biotinylated
TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells …
Color and Shape:
Liquid
Molecular weight:
20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-24 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-00121
| 1mg | 5,169.00 € | ||
| 100µg | 799.00 € | ||
| 500µg | 3,089.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
TNF α Protein, Rabbit, Recombinant
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily.
Purity:
98% - > 99.9%
Color and Shape:
Liquid
Molecular weight:
18 KDa (reducing condition)
Ref: TM-TMPJ-00779
| 10µg | 96.00 € | ||
| 20µg | 154.00 € | ||
| 50µg | 280.00 € | ||
| 100µg | 439.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
TNF α Protein, Human, Recombinant (aa 77-233, His)
TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E.
Purity:
SDS-PAGE: 100%; SEC-HPLC: 99% - SDS-PAGE: 99.66%; SEC-HPLC: 96.3%
Color and Shape:
Liquid
Molecular weight:
16 KDa (reducing condition)
Ref: TM-TMPJ-00124
| 1mg | 1,039.00 € | ||
| 10µg | 62.00 € | ||
| 50µg | 134.00 € | ||
| 500µg | 725.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
TNF α Protein, Human, Recombinant (His & Avi)
TNF alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with …
Color and Shape:
Liquid
Molecular weight:
20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-25 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-00120
| 1mg | 2,212.00 € | ||
| 100µg | 348.00 € | ||
| 500µg | 1,372.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
TNF α Protein, Cynomolgus, Recombinant (His)
TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag.
Color and Shape:
Liquid
Molecular weight:
18.35 kDa (predicted). Due to glycosylation, the protein migrates to 19-25 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-00119
| 1mg | 3,089.00 € | ||
| 100µg | 488.00 € | ||
| 500µg | 1,853.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
Tulisokibart
CAS:2648504-55-4
Tulisokibart (PRA023) is a humanized anti-TNFSF15 monoclonal antibody used to study colon cancer.
Color and Shape:
Liquid
Ref: TM-T80560
| 1mg | 234.00 € | ||
| 5mg | 688.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
TNF α Protein, Human, Recombinant (aa 57-233, His)
TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E.
Color and Shape:
Liquid
Molecular weight:
18 KDa (reducing condition)
Ref: TM-TMPJ-00125
| 1mg | 2,822.00 € | ||
| 10µg | 185.00 € | ||
| 50µg | 535.00 € | ||
| 500µg | 1,967.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
Fisetin
CAS:528-48-3
Fisetin belongs to a group of natural flavonols with anti-inflammatory, antioxidant, anti-tumor, anti-aging and neuroprotective …
Formula:
C15H10O6
Purity:
94.14% - 98.31%
Color and Shape:
Yellow To Brown Crystalline Powder
Molecular weight:
286.24
Ref: TM-T2879
| 100mg | 53.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
