TNF
TNF (Tumor Necrosis Factor) inhibitors are compounds that block the activity of TNF, a cytokine involved in inflammation and the regulation of apoptosis. TNF can induce apoptosis in some cell types while promoting survival and inflammation in others. Inhibiting TNF is crucial in the treatment of autoimmune diseases, chronic inflammatory conditions, and certain cancers. TNF inhibitors help to modulate the immune response and reduce tissue damage caused by excessive inflammation. At CymitQuimica, we provide a diverse range of high-quality TNF inhibitors to support your research in immunology, inflammation, and apoptosis.
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Cot inhibitor-2
CAS:915363-56-3
Cot inhibitor-2: Potent, selective Tpl2/MAP3K8 blocker. IC50: 1.6 nM; hampers LPS-induced TNF-α, IC50: 0.3 μM. …
Formula:
C26H25Cl2FN8
Purity:
98.87%
Color and Shape:
Solid
Molecular weight:
539.43
Ref: TM-T10866
| 1mg | 92.00 € | ||
| 2mg | 135.00 € | ||
| 5mg | 215.00 € | ||
| 10mg | 349.00 € | ||
| 25mg | 720.00 € | ||
| 50mg | 1,264.00 € | ||
| 100mg | 2,080.00 € | ||
| 500mg | 4,161.00 € | ||
| 1mL*10mM (DMSO) | 255.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
TNF-α-IN-1
CAS:444287-49-4
TNF-α-IN-1 is a TNF-α inhibitor.
Formula:
C16H14ClN3O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
363.75
Ref: TM-T13175
| 2mg | 84.00 € | ||
| 5mg | 127.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 370.00 € | ||
| 100mg | 775.00 € | ||
| 1mL*10mM (DMSO) | 215.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
Alethine
CAS:646-08-2
Alethine is a small antitumor compound used to treat cancers and infections, boosting T-cell cytotoxicity …
Formula:
C10H22N4O2S2
Purity:
98.82%
Color and Shape:
Solid
Molecular weight:
294.44
Ref: TM-T29857
| 1mg | 94.00 € | ||
| 5mg | 205.00 € | ||
| 10mg | 303.00 € | ||
| 25mg | 490.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
VU0285655-1
CAS:1158347-73-9
VU0285655-1, a PLD2 inhibitor, halts PLD2-deficient cell growth and protects against high glucose-induced cell death. …
Formula:
C25H27N5O2
Purity:
99.73%
Color and Shape:
Solid
Molecular weight:
429.51
Ref: TM-T26326
| 1mg | 86.00 € | ||
| 5mg | 180.00 € | ||
| 10mg | 298.00 € | ||
| 25mg | 620.00 € | ||
| 50mg | 870.00 € | ||
| 100mg | 1,169.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
Infliximab
CAS:170277-31-3
Infliximab is a chimeric monoclonal antibody that inhibits TNF-α. Infliximab can be used to treat …
Purity:
98% - 99.70%
Color and Shape:
Liquid
Molecular weight:
149 kDa
Ref: TM-T9921
| 1mg | 97.00 € | ||
| 2mg | 159.00 € | ||
| 5mg | 259.00 € | ||
| 25mg | 630.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
SPD304 dihydrochloride
CAS:1049741-03-8
SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 …
Formula:
C32H34Cl2F3N3O2
Purity:
99.25%
Color and Shape:
Solid
Molecular weight:
620.53
Ref: TM-T12985
| 1mg | 66.00 € | ||
| 5mg | 144.00 € | ||
| 10mg | 216.00 € | ||
| 25mg | 454.00 € | ||
| 50mg | 655.00 € | ||
| 100mg | 933.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
Selicrelumab
CAS:1622140-49-1
Selicrelumab (RG-7876) is an antibody targeting CD40 with potential anti-tumor activity for the study of …
Purity:
95% - 95%
Color and Shape:
Liquid
Ref: TM-T78250
| 1mg | 199.00 € | ||
| 5mg | 487.00 € | ||
| 10mg | 688.00 € | ||
| 25mg | 999.00 € | ||
| 50mg | 1,397.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
cRIPGBM
CAS:2361988-76-1
cRIPGBM induces apoptosis in GBM CSCs by targeting RIPK2, with an EC50 of 68 nM …
Formula:
C26H20FN2O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
411.45
Ref: TM-T19250
| 25mg | 2,033.00 € | ||
| 50mg | 2,645.00 € | ||
| 100mg | 3,345.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
Cot inhibitor-1
CAS:915365-57-0
Cot inhibitor-1 selectively blocks Tpl2 kinase, reducing TNF-alpha in blood (IC50: 5.7 nM). It may …
Formula:
C27H27Cl2FN8
Purity:
99.19%
Color and Shape:
Solid
Molecular weight:
553.46
Ref: TM-T10865
| 1mg | 89.00 € | ||
| 5mg | 203.00 € | ||
| 10mg | 318.00 € | ||
| 25mg | 568.00 € | ||
| 50mg | 874.00 € | ||
| 100mg | 1,454.00 € | ||
| 1mL*10mM (DMSO) | 245.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
Mitazalimab
CAS:2055640-86-1
Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels …
Purity:
95% - 95%
Color and Shape:
Liquid
Ref: TM-T77090
| 1mg | 235.00 € | ||
| 5mg | 612.00 € | ||
| 10mg | 938.00 € | ||
| 25mg | 1,454.00 € | ||
| 50mg | 1,882.00 € | ||
| 100mg | 2,650.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
GSK2593074A
CAS:1337531-06-2
GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.
Formula:
C27H23N5OS
Purity:
100%
Color and Shape:
Solid
Molecular weight:
465.57
Ref: TM-T11484
| 1mg | 114.00 € | ||
| 5mg | 274.00 € | ||
| 10mg | 432.00 € | ||
| 25mg | 725.00 € | ||
| 50mg | 1,017.00 € | ||
| 100mg | 1,359.00 € | ||
| 1mL*10mM (DMSO) | 303.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
UCB-5307
CAS:1515887-44-1
UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and …
Formula:
C22H21N3O
Purity:
98.02%
Color and Shape:
Liquid
Molecular weight:
343.42
Ref: TM-T61111
| 1mg | 56.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 429.00 € | ||
| 50mg | 630.00 € | ||
| 100mg | 898.00 € | ||
| 500mg | 1,786.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
(R)-STU104
CAS:2767124-77-4
(R)-STU104 is a TAK1-MKK3 protein-protein interaction (PPI) inhibitor. (R)-STU104 is a candidate compound for the …
Formula:
C18H18O4
Purity:
98.91%
Color and Shape:
Liquid
Molecular weight:
298.33
Ref: TM-T60657
| 1mg | 81.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 259.00 € | ||
| 25mg | 444.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
L6H21
CAS:24533-47-9
L6H21 is an MD-2 inhibitor that can be used to study cognitive impairment and brain …
Formula:
C18H18O4
Purity:
99.26%
Color and Shape:
Liquid
Molecular weight:
298.33
Ref: TM-T69626
| 1mg | 35.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 106.00 € | ||
| 25mg | 227.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 597.00 € |
Estimated delivery in United States, on Tuesday 10 Jun 2025
RIPK-IN-4
CAS:2141969-56-2
RIPK-IN-4 is an effective and selective inhibitor of RIPK2. It also has excellent oral bioavailability …
Formula:
C18H21FN4O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
392.45
Ref: TM-T16755
| 25mg | 1,359.00 € | ||
| 50mg | 1,768.00 € | ||
| 100mg | 2,680.00 € |
Estimated delivery in United States, on Monday 23 Jun 2025
Trovafloxacin mesylate
CAS:147059-75-4
Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).
Formula:
C21H19F3N4O6S
Purity:
99.12%
Color and Shape:
Solid
Molecular weight:
512.46
Ref: TM-T13231L
| 1mg | 37.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 187.00 € | ||
| 50mg | 365.00 € | ||
| 100mg | 550.00 € | ||
| 1mL*10mM (DMSO) | 99.00 € |
Estimated delivery in United States, on Monday 23 Jun 2025
C 87
CAS:332420-90-3
C 87: Small-molecule TNF-α inhibitor, binds TNFα, inhibits cytotoxicity with IC50 of 8.73 μM, blocks …
Formula:
C24H15ClN6O3S
Purity:
≥98%
Color and Shape:
Solid
Molecular weight:
502.93
Ref: TM-T14848
| 2mg | 47.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 23 Jun 2025
BMS-561392
CAS:611227-74-8
BMS-561392 (DPC333) is a tumor necrosis factor-α ( TNF-α) Invertase inhibitor.
Formula:
C27H32N4O4
Purity:
99.16%
Color and Shape:
Solid
Molecular weight:
476.57
Ref: TM-T30531
| 25mg | 1,096.00 € | ||
| 1mL*10mM (DMSO) | 502.00 € |
Estimated delivery in United States, on Monday 23 Jun 2025
PK68
CAS:2173556-69-7
PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.
Formula:
C22H24N4O3S
Purity:
98.13%
Color and Shape:
Solid
Molecular weight:
424.52
Ref: TM-T12493
| 1mg | 88.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 274.00 € | ||
| 25mg | 520.00 € | ||
| 50mg | 750.00 € | ||
| 100mg | 1,026.00 € | ||
| 500mg | 2,080.00 € | ||
| 1mL*10mM (DMSO) | 188.00 € |
Estimated delivery in United States, on Monday 23 Jun 2025
CDC801
CAS:192819-27-5
CDC801 is an inhibitor of PDE4 and TNF-α with IC50s of 1.1 μM and 2.5 …
Formula:
C23H24N2O5
Purity:
98.81%
Color and Shape:
Solid
Molecular weight:
408.45
Ref: TM-T10730
| 1mg | 170.00 € | ||
| 2mg | 226.00 € | ||
| 5mg | 354.00 € | ||
| 10mg | 505.00 € | ||
| 25mg | 758.00 € | ||
| 50mg | 1,017.00 € | ||
| 100mg | 1,378.00 € |
Estimated delivery in United States, on Monday 23 Jun 2025
