TNF
TNF (Tumor Necrosis Factor) inhibitors are compounds that block the activity of TNF, a cytokine involved in inflammation and the regulation of apoptosis. TNF can induce apoptosis in some cell types while promoting survival and inflammation in others. Inhibiting TNF is crucial in the treatment of autoimmune diseases, chronic inflammatory conditions, and certain cancers. TNF inhibitors help to modulate the immune response and reduce tissue damage caused by excessive inflammation. At CymitQuimica, we provide a diverse range of high-quality TNF inhibitors to support your research in immunology, inflammation, and apoptosis.
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| Brand | Product data | Purity | Price range | Estimated delivery |
|---|---|---|---|---|
 | RIPK-IN-4 REF: TM-T16755CAS: 2141969-56-2 | 98% | 144.00 €~2,626.00 € | Wed 05 Feb 25 |
| PK68 REF: TM-T12493CAS: 2173556-69-7 | 98.13% | 87.00 €~2,034.00 € | Wed 05 Feb 25 |
| GNE684 REF: TM-T11442CAS: 2438637-64-8 | 98% | To inquire | Wed 05 Mar 25 |
| SPD304 REF: TM-T12985LCAS: 869998-49-2 | 98% | - - - | Discontinued product |
| Nec-4 REF: TM-T12202CAS: 1041644-43-2 | 98% | - - - | Discontinued product |
RIPK-IN-4
CAS:2141969-56-2
RIPK-IN-4 is an effective and selective inhibitor of RIPK2. It also has excellent oral bioavailability …
Formula:
C18H21FN4O3S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
392.45
Ref: TM-T16755
| 25mg | 1,327.00 € | ||
| 50mg | 1,722.00 € | ||
| 100mg | 2,626.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
PK68
CAS:2173556-69-7
PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.
Formula:
C22H24N4O3S
Purity:
98.13%
Color and Shape:
Solid
Molecular weight:
424.52
Ref: TM-T12493
| 1mg | 87.00 € | ||
| 5mg | 171.00 € | ||
| 10mg | 270.00 € | ||
| 25mg | 510.00 € | ||
| 50mg | 733.00 € | ||
| 100mg | 1,007.00 € | ||
| 500mg | 2,034.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Wednesday 5 Feb 2025
GNE684
CAS:2438637-64-8
GNE684 inhibits RIP1; Ki app: 21 nM (human), 189 nM (mouse), 691 nM (rat).
Formula:
C23H24N6O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
432.48
Ref: TM-T11442
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Wednesday 5 Mar 2025
SPD304
CAS:869998-49-2
SPD304, selective TNF-α blocker, inhibits TNF receptor 1 binding with 22 µM IC50.
Formula:
C32H32F3N3O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
547.61
Ref: TM-T12985L
| 1mg | Discontinued | Request information | |
| 5mg | Discontinued | Request information | |
| 10mg | Discontinued | Request information | |
| 25mg | Discontinued | Request information | |
| 50mg | Discontinued | Request information | |
| 100mg | Discontinued | Request information | |
| 200mg | Discontinued | Request information | |
| 500µg | Discontinued | Request information | |
| 1ml*10 (DMSO) | Discontinued | Request information |
Nec-4
CAS:1041644-43-2
Nec-4 is a potent inhibitor of receptor interacting protein 1 (RIP1)(IC50 of 2.6 μM),and is …
Formula:
C15H13ClFN3O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
305.73
Ref: TM-T12202
| 5mg | Discontinued | Request information | |
| 25mg | Discontinued | Request information | |
| 50mg | Discontinued | Request information | |
| 100mg | Discontinued | Request information |
