TNF
TNF (Tumor Necrosis Factor) inhibitors are compounds that block the activity of TNF, a cytokine involved in inflammation and the regulation of apoptosis. TNF can induce apoptosis in some cell types while promoting survival and inflammation in others. Inhibiting TNF is crucial in the treatment of autoimmune diseases, chronic inflammatory conditions, and certain cancers. TNF inhibitors help to modulate the immune response and reduce tissue damage caused by excessive inflammation. At CymitQuimica, we provide a diverse range of high-quality TNF inhibitors to support your research in immunology, inflammation, and apoptosis.
Found 92 products of "TNF"
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UCB-9260
CAS:<p>UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.</p>Formula:C26H25N5OPurity:98.39% - 99.24%Color and Shape:SolidMolecular weight:423.51Teneliximab
CAS:<p>Teneliximab (BMS 224819) is a chimeric monoclonal antibody that blocks CD40-CD40L interactions.Cost-effective and quality-assured.</p>Purity:95.00% - 99.19% (SEC-HPLC)Color and Shape:LiquidMolecular weight:146.06 kDaOzoralizumab
CAS:<p>Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.</p>Purity:SDS-PAGE:> 95%;SEC-HPLC:95.6%Color and Shape:LiquidMolecular weight:38.44 kDaEnavatuzumab
CAS:<p>Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting TWEAK receptor with anti-tumor activity.</p>Purity:>95%Color and Shape:LiquidLucatumumab
CAS:<p>Lucatumumab (HCD122) is a fully human anti-CD40 monoclonal antibody with anti-tumor activity for the study of multiple myeloma.</p>Purity:95.5% (SDS-PAGE); 98.4% (SEC-HPLC) - 95.5% (SDS-PAGE); 98.4% (SEC-HPLC)Color and Shape:LiquidCertolizumab pegol
CAS:<p>Certolizumab pegol (Certolizumab) is a polyethylene glycolized and humanized anti-TNF-α monoclonal antibody.</p>Purity:95% - 98.2% (SDS-PAGE); 99.1% (SEC-HPLC)Color and Shape:LiquidUtomilumab
CAS:<p>Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.</p>Formula:C17H24N8O3Purity:95% - 95.1% (SDS-PAGE); 98.5% (SEC-HPLC)Color and Shape:LiquidMolecular weight:142.77 kDaIscalimab
CAS:<p>Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren’s syndrome.</p>Purity:>95%Color and Shape:Liquid(S,S)-TAPI-1 FA
<p>(S,S)-TAPI-1 FA is a TNF-α processing inhibitor with potential anti-inflammatory effects, blocks TACE, and can inhibit TNF-α signaling can be used to study Staphylococcus aureus arthritis.</p>Formula:C27H39N5O7Purity:97.61% - 99.72%Color and Shape:SolidMolecular weight:545.63Conatumumab
CAS:<p>Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).</p>Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:145 kDa (average)Dacetuzumab
CAS:<p>Dacetuzumab (SGN 40) is a humanized anti-CD40 monoclonal antibody with antitumor activity for the study of recurrent diffuse large B-cell lymphoma.</p>Purity:95.4% (SDS-PAGE); 99.1% (SEC-HPLC) - 95.4% (SDS-PAGE); 99.1% (SEC-HPLC)Color and Shape:LiquidRuplizumab
CAS:<p>PF-03732010 is a humanized antibody targeting P-calmodulin with antitumor and antimetastatic activity.</p>Purity:98.5% (SDS-PAGE); 98.7% (SEC-HPLC) - 98.5% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:LiquidTNF-α-IN-9
CAS:<p>TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.</p>Formula:C17H14O4Purity:98.28%Color and Shape:SoildMolecular weight:282.29Varlilumab
CAS:<p>Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.</p>Purity:SDS-PAGE:95% SEC-HPLC:98.65%Color and Shape:LiquidMolecular weight:146 kDaAsunercept
CAS:<p>Asunercept (APG101/CAN008) is a CD95-Fc protein targeting CD95L, used in GBM, MDS, and GvHD research.</p>Color and Shape:LiquidTanfanercept
CAS:<p>Tanfanercept (HL036337) is an anti-TNF-α antibody, improving corneal erosions in dry eye mice.</p>Color and Shape:LiquidRagifilimab
CAS:<p>Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.</p>Purity:SDS-PAGE:95% SEC-HPLC:99.99%Color and Shape:LiquidMolecular weight:146.46 kDaTengonermin
CAS:<p>Tengonermin (ARENEGYR), a vascular agent, is TNF-α fused with CNGRCG peptide, enhancing chemo and T-cell access in tumors.</p>Color and Shape:LiquidPegsunercept
CAS:<p>Pegsunercept (PEG sTNF-RI), a pegylated monoclonal antibody, selectively binds to TNFA, incorporating a polyethylene glycol (pegol) moiety [1].</p>Color and Shape:LiquidZigakibart
CAS:<p>Zigakibart (BION-1301) is a humanized monoclonal antibody targeting TNFSF13 with anti-inflammatory activity for the study of immunoglobulin A nephropathy (IgAN)</p>Purity:95.8% (SDS-PAGE); 99.8% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.8% (SEC-HPLC)Color and Shape:Liquid
