TNF
TNF (Tumor Necrosis Factor) inhibitors are compounds that block the activity of TNF, a cytokine involved in inflammation and the regulation of apoptosis. TNF can induce apoptosis in some cell types while promoting survival and inflammation in others. Inhibiting TNF is crucial in the treatment of autoimmune diseases, chronic inflammatory conditions, and certain cancers. TNF inhibitors help to modulate the immune response and reduce tissue damage caused by excessive inflammation. At CymitQuimica, we provide a diverse range of high-quality TNF inhibitors to support your research in immunology, inflammation, and apoptosis.
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UCB-9260
CAS:1515888-53-5
UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.
Formula:
C26H25N5O
Purity:
98.39% - 99.24%
Color and Shape:
Solid
Molecular weight:
423.51
Ref: TM-T13951
| 1mg | 97.00 € | ||
| 5mg | 230.00 € | ||
| 10mg | 384.00 € | ||
| 25mg | 642.00 € | ||
| 50mg | 914.00 € | ||
| 100mg | 1,216.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Amrinone
CAS:60719-84-8
Amrinone (Inocor) is a positive inotropic cardiotonic (cardiotonic agent) with vasodilator properties, phosphodiesterase 3 inhibitory …
Formula:
C10H9N3O
Purity:
98.88% - 99.45%
Color and Shape:
Solid
Molecular weight:
187.2
Ref: TM-T1265
| 50mg | 47.00 € | ||
| 100mg | 74.00 € | ||
| 200mg | 96.00 € | ||
| 500mg | 157.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
4-methoxylonchocarpin
CAS:51589-67-4
4-methoxylonchocarpin, from Abrus precatorius roots, inhibits NF-κB, LPS/TLR4 in macrophages, and mouse colitis.
Formula:
C21H20O4
Purity:
98%
Color and Shape:
Soild
Molecular weight:
336.38
Ref: TM-TN7235
| 1mg | 185.00 € | ||
| 5mg | 465.00 € | ||
| 10mg | 680.00 € | ||
| 25mg | 1,035.00 € | ||
| 50mg | 1,406.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Cot inhibitor-1 hydrochloride
Cot inhibitor-1 hydrochloride blocks TPL-2 kinase (IC50=28nM) and TNF-α synthesis (IC50=5.7nM) in human blood.
Formula:
C27H28Cl3FN8
Purity:
98.26%
Color and Shape:
Soild
Molecular weight:
589.92
Ref: TM-T10865L
| 1mg | 125.00 € | ||
| 5mg | 240.00 € | ||
| 10mg | 379.00 € | ||
| 25mg | 632.00 € | ||
| 50mg | 899.00 € | ||
| 100mg | 1,216.00 € | ||
| 1mL*10mM (DMSO) | 283.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Hernandezine
CAS:6681-13-6
Hernandezine is an activator of AMPK activator and a selective reversing agent for ABCB1-mediated MDR …
Formula:
C39H44N2O7
Purity:
99.53%
Color and Shape:
Solid
Molecular weight:
652.78
Ref: TM-TN1731
| 1mg | 154.00 € | ||
| 5mg | 354.00 € | ||
| 10mg | 512.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Tebentafusp
CAS:1874157-95-5
Tebentafusp (IMCgp100) is a protein that targets gp100 with potential anti-tumor activity.
Color and Shape:
Liquid
Ref: TM-T76843
| 1mg | 588.00 € | ||
| 5mg | 944.00 € | ||
| 10mg | 1,510.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Certolizumab pegol
CAS:428863-50-7
Certolizumab pegol (Certolizumab) is a polyethylene glycolized and humanized anti-TNF-α monoclonal antibody.
Color and Shape:
Liquid
Ref: TM-T76963
| 1mg | 144.00 € | ||
| 5mg | 298.00 € | ||
| 10mg | 472.00 € | ||
| 25mg | 753.00 € | ||
| 50mg | 1,017.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Zigakibart
CAS:2642175-46-8
Zigakibart (BION-1301) is a humanized monoclonal antibody targeting TNFSF13 with anti-inflammatory activity for the study …
Color and Shape:
Liquid
Ref: TM-T80730
| 1mg | 274.00 € | ||
| 5mg | 747.00 € | ||
| 10mg | 1,169.00 € | ||
| 25mg | 1,738.00 € | ||
| 50mg | 2,357.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Ragifilimab
CAS:2207590-51-8
Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.
Purity:
SDS-PAGE:95% SEC-HPLC:99.99%
Color and Shape:
Liquid
Molecular weight:
146.46 kDa
Ref: TM-T77138
| 1mg | 137.00 € | ||
| 5mg | 329.00 € | ||
| 10mg | 543.00 € | ||
| 25mg | 873.00 € | ||
| 50mg | 1,188.00 € | ||
| 100mg | 1,605.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Belantamab
CAS:2061894-48-0
Belantamab (GSK2857914) is a humanized IgG1 monoclonal antibody targeting BCMA, used for creating conjugates like …
Purity:
SDS-PAGE:95% SEC-HPLC:99.99%
Color and Shape:
Liquid
Molecular weight:
146.06 kDa
Ref: TM-T77129
| 1mg | 250.00 € | ||
| 5mg | 567.00 € | ||
| 10mg | 908.00 € | ||
| 25mg | 1,349.00 € | ||
| 50mg | 1,825.00 € | ||
| 100mg | 2,460.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea
CAS:2379727-88-3
1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea 是一种能够激动 TNF-α的化合物,可以诱导细胞分泌 TNF-α。
Formula:
C24H21ClF3N5O
Purity:
97.90% - 98.61%
Color and Shape:
Soild
Molecular weight:
487.9
Ref: TM-T60124
| 1mg | 77.00 € | ||
| 5mg | 158.00 € | ||
| 10mg | 225.00 € | ||
| 25mg | 375.00 € | ||
| 1mL*10mM (DMSO) | 183.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Conatumumab
CAS:896731-82-1
Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM …
Purity:
> 95% - > 95%
Color and Shape:
Liquid
Molecular weight:
145 kDa (average)
Ref: TM-T76787
| 1mg | 359.00 € | ||
| 5mg | 908.00 € | ||
| 10mg | 1,454.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Varlilumab
CAS:1393344-72-3
Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and …
Purity:
SDS-PAGE:95% SEC-HPLC:98.65%
Color and Shape:
Liquid
Molecular weight:
146 kDa
Ref: TM-T76706
| 1mg | 590.00 € | ||
| 5mg | 2,015.00 € | ||
| 10mg | 2,717.00 € | ||
| 25mg | 4,019.00 € | ||
| 50mg | 5,444.00 € | ||
| 100mg | 7,344.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Teneliximab
CAS:299423-37-3
Teneliximab (BMS 224819) is a chimeric monoclonal antibody that blocks CD40-CD40L interactions.Cost-effective and quality-assured.
Purity:
95.00% - 99.19% (SEC-HPLC)
Color and Shape:
Liquid
Molecular weight:
146.06 kDa
Ref: TM-T76830
| 1mg | 160.00 € | ||
| 5mg | 406.00 € | ||
| 10mg | 628.00 € | ||
| 25mg | 938.00 € | ||
| 50mg | 1,301.00 € | ||
| 100mg | 1,758.00 € | ||
| 200mg | 2,365.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
TNF-α-IN-9
CAS:2054199-25-4
TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.
Formula:
C17H14O4
Purity:
98.28%
Color and Shape:
Soild
Molecular weight:
282.29
Ref: TM-T77494
| 1mg | 48.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 133.00 € | ||
| 25mg | 217.00 € | ||
| 50mg | 329.00 € | ||
| 100mg | 472.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Anti-Mouse TNF α Antibody (TN3-19.12)
Anti-Mouse TNF alpha Antibody is a rat-derived IgG inhibitor targeting mouse TNF alpha.
Purity:
95% - ＞10mg/ml
Ref: TM-T78272
| 1mg | 309.00 € | ||
| 5mg | 752.00 € | ||
| 10mg | 1,026.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Ruplizumab
CAS:220651-94-5
PF-03732010 is a humanized antibody targeting P-calmodulin with antitumor and antimetastatic activity.
Purity:
95% - 95%
Color and Shape:
Liquid
Ref: TM-T76825
| 1mg | 230.00 € | ||
| 5mg | 602.00 € | ||
| 10mg | 822.00 € | ||
| 25mg | 1,216.00 € | ||
| 50mg | 1,644.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Eupatolide
CAS:6750-25-0
Eupatolide, from Inula japonica flowers, has anti-inflammatory properties and aids in researching TRAIL resistance in …
Formula:
C15H20O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
248.32
Ref: TM-TN4038
| 1mg | 283.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Etanercept
CAS:185243-69-0
Etanercept is a fusion protein consisting of the soluble portion of the p75-tumor necrosis factor …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T37445
| 1mg | 311.00 € | ||
| 5mg | 630.00 € | ||
| 10mg | 945.00 € | ||
| 25mg | 1,396.00 € | ||
| 50mg | 1,890.00 € | ||
| 100mg | 2,547.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
Atibuclimab
CAS:2417175-94-9
Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and …
Purity:
> 95% - > 95%
Color and Shape:
Liquid
Molecular weight:
145.28 kDa
Ref: TM-T77484
| 1mg | 127.00 € | ||
| 5mg | 349.00 € | ||
| 10mg | 533.00 € | ||
| 25mg | 845.00 € | ||
| 50mg | 1,130.00 € | ||
| 100mg | 1,510.00 € |
Estimated delivery in United States, on Wednesday 16 Apr 2025
