TNF
TNF (Tumor Necrosis Factor) inhibitors are compounds that block the activity of TNF, a cytokine involved in inflammation and the regulation of apoptosis. TNF can induce apoptosis in some cell types while promoting survival and inflammation in others. Inhibiting TNF is crucial in the treatment of autoimmune diseases, chronic inflammatory conditions, and certain cancers. TNF inhibitors help to modulate the immune response and reduce tissue damage caused by excessive inflammation. At CymitQuimica, we provide a diverse range of high-quality TNF inhibitors to support your research in immunology, inflammation, and apoptosis.
Found 65 products of "TNF"
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Certolizumab pegol
CAS:Certolizumab pegol (Certolizumab) is a polyethylene glycolized and humanized anti-TNF-α monoclonal antibody.Purity:96.7% (SDS-PAGE); 96.5% (SEC-HPLC) - 98.2% (SDS-PAGE); 99.1% (SEC-HPLC)Color and Shape:LiquidMolecular weight:47.74 kDa(S,S)-TAPI-1 FA
(S,S)-TAPI-1 FA is a TNF-α processing inhibitor with potential anti-inflammatory effects, blocks TACE, and can inhibit TNF-α signaling can be used to study Staphylococcus aureus arthritis.Formula:C27H39N5O7Purity:97.61% - 99.72%Color and Shape:SolidMolecular weight:545.63Conatumumab
CAS:Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:145.44 kDaUCB-9260
CAS:UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.Formula:C26H25N5OPurity:98.39% - 99.24%Color and Shape:SolidMolecular weight:423.51Ref: TM-T13951
1mg92.00€2mg133.00€5mg219.00€10mg353.00€25mg602.00€50mg802.00€100mg1,108.00€200mg1,485.00€1mL*10mM (DMSO)245.00€Utomilumab
CAS:Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.Formula:C17H24N8O3Purity:95% - 95.1% (SDS-PAGE); 98.5% (SEC-HPLC)Color and Shape:LiquidMolecular weight:142.77 kDaLenercept
CAS:Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].Color and Shape:LiquidDSTYSLSSTLTLSK TFA
DSTYSLSSTLTLSK TFA detects infliximab, a chimeric IgG1 antibody targeting TNF-α.Formula:C66H108F3N15O28Color and Shape:SolidMolecular weight:1616.64Efaprinermin alfa
CAS:Efaprimermin alfa (OMP-336B11) is a human monoclonal antibody that targets TNFRSF18, and functions as a GITR ligand-Fc fusion protein [1].Color and Shape:LiquidRO7567132
RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.Color and Shape:Odour LiquidTNF-α Antagonist
CAS:TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction withFormula:C58H71N11O15S2Color and Shape:SolidMolecular weight:1226.39Varlilumab
CAS:Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.Purity:SDS-PAGE:95% SEC-HPLC:98.65%Color and Shape:LiquidMolecular weight:146 kDaTNF-α (46-65), human
CAS:Human TNF alpha (46-65) peptide.Formula:C110H172N24O30Purity:98%Color and Shape:SolidMolecular weight:2310.69Pamlectabart
Pamlectabart is a humanised antibody targeting TNFRSF17/BCMA, (ADC) Pamlectabart tismanitin multiple myeloma.Purity:95%Color and Shape:LiquidMolecular weight:145.20 kDaTengonermin
CAS:Tengonermin (ARENEGYR), a vascular agent, is TNF-α fused with CNGRCG peptide, enhancing chemo and T-cell access in tumors.Color and Shape:LiquidOnercept
CAS:Onercept, a recombinant soluble form of the human tumor necrosis factor-alpha (TNF-α) p55 receptor, is utilized in the study of Crohn's disease [1].Color and Shape:LiquidRagifilimab
CAS:Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.
Purity:SDS-PAGE:95% SEC-HPLC:99.99%Color and Shape:LiquidMolecular weight:146.46 kDaKGYY15
CAS:KGYY15 (Mouse KGYY15), a peptide that targets CD40, exhibits weak inhibition of the CD40-CD40L interaction, with an IC50 exceeding 1 mM. At a concentration of 100 μM, KGYY15 activates the NF-κB pathway by 33%.Formula:C84H129N21O22SColor and Shape:SolidMolecular weight:1817.12Acetyl tetrapeptide-2
CAS:Acetyl tetrapeptide-2 is a skin conditioner, by soothing and nourishing the skin through similar mechanisms as other peptides.Formula:C26H39N5O9Purity:98%Color and Shape:SolidMolecular weight:565.62TNF-α-IN-9
CAS:TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.Formula:C17H14O4Purity:99.21%Color and Shape:SoildMolecular weight:282.29MK-4166
MK-4166 is a humanized IgG1 agonistic monoclonal antibody targeting GITR. It is capable of enhancing the proliferation of both naive T lymphocytes and tumor-infiltrating T lymphocytes.
