Caspase
Caspase inhibitors are compounds that block the activity of caspases, a family of proteases that are central executors of apoptosis. Caspases cleave specific substrates within the cell to trigger the apoptotic process, leading to programmed cell death. Caspase inhibitors are used to study the mechanisms of apoptosis, as well as to prevent unwanted cell death in various research models. These inhibitors are also explored in therapeutic contexts to protect cells from apoptosis in diseases such as neurodegeneration. At CymitQuimica, we offer a wide range of high-quality caspase inhibitors to support your research in apoptosis, cell death, and related fields.
Found 154 products of "Caspase"
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GRI977143
CAS:GRI977143: selective LPA2 agonist (EC50=3.3μM), blocks caspases 3/7/8/9, limits DNA fragmentation.Formula:C22H17NO4SPurity:99.08%Color and Shape:SolidMolecular weight:391.44Caspase-9 Inhibitor III
CAS:Caspase-9 Inhibitor III (Ac-LEHD-cmk) blocks caspase-9, protects against ischemic heart damage.Formula:C24H35ClN6O9Color and Shape:SolidMolecular weight:587.02SDZ 224-015
CAS:SDZ 224-015 is an inhibitor of interleukin-1β (IL-1β) converting enzyme and caspase-1 with anti-COVID-19 and anti-inflammatory activity.Formula:C30H35Cl2N3O9Purity:95.49% - 95.49%Color and Shape:SolidMolecular weight:652.52ML132
CAS:ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316 nM).Formula:C22H28ClN5O5Color and Shape:SolidMolecular weight:477.942-chloro Palmitic Acid
CAS:2-chloro Palmitic acid triggers NETosis, elevates COX-2, adhesion molecules in HCAECs, and induces apoptosis and caspase-3 in THP-1 cells/monocytes.Formula:C16H31ClO2Color and Shape:SolidMolecular weight:290.87S1QEL1.1
CAS:S1QEL1.1 (S1QEL) is an electron leakage inhibitor that inhibits O2-induced ROS generation and prevents O2-induced DA closure.Formula:C23H24N4O3SPurity:99.93%Color and Shape:SolidMolecular weight:436.53Caspase-3-IN-1
CAS:Caspase-3-IN-1 is a potent inhibitor of Caspase-3 (IC50: 14.5 nM).Formula:C26H25N3O6SColor and Shape:SolidMolecular weight:507.56p-nitro-Pifithrin-α
CAS:p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor.Formula:C15H16BrN3O3SColor and Shape:SolidMolecular weight:398.27OT-82
CAS:OT-82 is a NAMPT inhibitor with anticancer activity and cytotoxicity and is used in the study of leukemias.Formula:C26H21FN4OPurity:98.91% - 99.315%Color and Shape:SolidMolecular weight:424.47Ref: TM-T12330
2mg137.00€5mg222.00€10mg356.00€25mg708.00€50mg1,108.00€100mg1,468.00€1mL*10mM (DMSO)245.00€Anisperimus
CAS:Anisperimus (LF 15-0195) is an immunosuppressant that prevents CNS autoimmunity by promoting the development of regulatory CD4 T cells expressing Foxp3.Formula:C18H39N7O3Purity:98.10%Color and Shape:SolidMolecular weight:401.55Tigilanol tiglate
CAS:Tigilanol tiglate (EBC-46) is a PKC/C1 domain activator. Tigilanol tiglate induces immunogenic cell death and tumour regression.Formula:C30H42O10Purity:98%Color and Shape:SolidMolecular weight:562.65CZL55
CAS:CZL55 is a potent caspase-1 inhibitor with an IC50 value of 0.024 μM.CZL55 has low cytotoxicity and can be used in the study of febrile seizures (FS).Formula:C20H22N2O6Purity:98.19%Color and Shape:SolidMolecular weight:386.4EP1013
CAS:EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes.Formula:C18H23FN2O6Purity:98%Color and Shape:SolidMolecular weight:382.38Ac-VAD-CHO
CAS:Ac-Val-Ala-Asp-CHO (Ac-VAD-CHO) serves as a pan-caspase inhibitor and preserves mitochondrial membrane potential (MMP) while preventing the release ofFormula:C14H23N3O6Purity:98%Color and Shape:SolidMolecular weight:329.35Ac-YVAD-pNA
CAS:Ac-YVAD-pNA, a specific substrate for Caspase-1, serves to detect Caspase-1 activity, a crucial mediator of inflammatory processes [1] [2].Formula:C29H36N6O10Color and Shape:SolidMolecular weight:628.639Z-YVAD-CMK
CAS:Z-YVAD-CMK is an inhibitor of both caspase-1 and caspase-3, as referenced in [1].Formula:C30H37ClN4O9Purity:98%Color and Shape:SolidMolecular weight:633.09M190S
CAS:M109S is a novel small molecule that shields cells from mitochondria-dependent apoptosis, demonstrating effectiveness both in vitro and in vivo.Formula:C21H21N5O2Purity:98%Color and Shape:SolidMolecular weight:375.42GDC-2394
CAS:GDC-2394: Oral, selective NLRP3 inhibitor; blocks IL-1β (human 0.4μM, mouse 0.1μM), spares NLRC4.Formula:C20H25N5O4SColor and Shape:SolidMolecular weight:431.51CIL62
CAS:CIL62 is a caspase-3/7-independent inducer of cell death. The mechanism of action of CIL62 is Necrostatin-1 dependent cell death [1].Formula:C23H26O5Purity:97.07%Color and Shape:SolidMolecular weight:382.45Ref: TM-T8468
1mg38.00€5mg86.00€10mg116.00€25mg222.00€50mg371.00€100mg504.00€200mg675.00€1mL*10mM (DMSO)94.00€M867
CAS:M867 is a selective, reversible caspase-3 inhibitor, possessing an IC50 of 1.4 nM and a Ki value of 0.7 nM, demonstrating anti-apoptotic activity [1].Formula:C27H43N7O6Purity:98%Color and Shape:SolidMolecular weight:561.67
