Caspase
Caspase inhibitors are compounds that block the activity of caspases, a family of proteases that are central executors of apoptosis. Caspases cleave specific substrates within the cell to trigger the apoptotic process, leading to programmed cell death. Caspase inhibitors are used to study the mechanisms of apoptosis, as well as to prevent unwanted cell death in various research models. These inhibitors are also explored in therapeutic contexts to protect cells from apoptosis in diseases such as neurodegeneration. At CymitQuimica, we offer a wide range of high-quality caspase inhibitors to support your research in apoptosis, cell death, and related fields.
Found 157 products for "Caspase".
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QM31
CAS:QM31 is a selective Apaf-1 inhibitor(inbitita formation of the apoptosome with IC50 of 7.9μM).Formula:C39H38Cl4N4O4Purity:98%Color and Shape:SolidMolecular weight:768.56N1,N11-Diethylnorspermine
CAS:DENSPM: potent anticancer, spurs polyamine breakdown, triggers cytochrome c release and caspase 3, kills GBM via SSAT & H2O2.Formula:C13H32N4Color and Shape:SolidMolecular weight:244.422-chloro Palmitic Acid
CAS:2-chloro Palmitic acid triggers NETosis, elevates COX-2, adhesion molecules in HCAECs, and induces apoptosis and caspase-3 in THP-1 cells/monocytes.Formula:C16H31ClO2Color and Shape:SolidMolecular weight:290.87GRI977143
CAS:GRI977143: selective LPA2 agonist (EC50=3.3μM), blocks caspases 3/7/8/9, limits DNA fragmentation.Formula:C22H17NO4SPurity:99.08%Color and Shape:SolidMolecular weight:391.44Caspase-9 Inhibitor III
CAS:Caspase-9 Inhibitor III (Ac-LEHD-cmk) blocks caspase-9, protects against ischemic heart damage.Formula:C24H35ClN6O9Color and Shape:SolidMolecular weight:587.02OT-82
CAS:OT-82 is a NAMPT inhibitor with anticancer activity and cytotoxicity and is used in the study of leukemias.Formula:C26H21FN4OPurity:98.91% - 99.31%Color and Shape:Brown ViscousMolecular weight:424.47Ref: TM-T12330
2mg137.00€5mg222.00€1mL*10mM (DMSO)245.00€10mg356.00€25mg708.00€50mg1,108.00€100mg1,468.00€p-nitro-Pifithrin-α
CAS:p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor.Formula:C15H16BrN3O3SColor and Shape:SolidMolecular weight:398.27Tigilanol tiglate
CAS:Tigilanol tiglate (EBC-46) is a PKC/C1 domain activator. Tigilanol tiglate induces immunogenic cell death and tumour regression.Formula:C30H42O10Purity:98%Color and Shape:White SolidMolecular weight:562.65Anisperimus
CAS:Anisperimus (LF 15-0195) is an immunosuppressant that prevents CNS autoimmunity by promoting the development of regulatory CD4 T cells expressing Foxp3.Formula:C18H39N7O3Purity:98.10%Color and Shape:White OilMolecular weight:401.55Caspase-3-IN-1
CAS:Caspase-3-IN-1 is a potent inhibitor of Caspase-3 (IC50: 14.5 nM).Formula:C26H25N3O6SColor and Shape:SolidMolecular weight:507.56ZYZ-488
CAS:ZYZ-488 is an Apoptosis protease activating factor-1 (Apaf-1) inhibitor, which suppresses the activation of procaspase-9 and procaspase-3.Formula:C20H29N3O11Purity:99.04%Color and Shape:White SolidMolecular weight:487.46Apoptotic agent-3
CAS:Apoptotic agent-3 is an apoptosis inducer; activates Caspase-3/7; antitumor proliferative activity; pharmacology research.Formula:C31H21N5OSPurity:99.31%Color and Shape:Yellow SolidMolecular weight:511.6ML132
CAS:ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316 nM).Formula:C22H28ClN5O5Color and Shape:SolidMolecular weight:477.94S1QEL1.1
CAS:S1QEL1.1 (S1QEL) is an electron leakage inhibitor that inhibits O2-induced ROS generation and prevents O2-induced DA closure.Formula:C23H24N4O3SPurity:99.93%Color and Shape:White SolidMolecular weight:436.53CZL55
CAS:CZL55 is a potent caspase-1 inhibitor with an IC50 value of 0.024 μM.CZL55 has low cytotoxicity and can be used in the study of febrile seizures (FS).Formula:C20H22N2O6Purity:98.73%Color and Shape:SolidMolecular weight:386.4EP1013
CAS:EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes.Formula:C18H23FN2O6Purity:98%Color and Shape:SolidMolecular weight:382.38Ac-VAD-CHO
CAS:Ac-Val-Ala-Asp-CHO (Ac-VAD-CHO) serves as a pan-caspase inhibitor and preserves mitochondrial membrane potential (MMP) while preventing the release ofFormula:C14H23N3O6Purity:98%Color and Shape:SolidMolecular weight:329.35GDC-2394
CAS:GDC-2394: Oral, selective NLRP3 inhibitor; blocks IL-1β (human 0.4μM, mouse 0.1μM), spares NLRC4.Formula:C20H25N5O4SColor and Shape:SolidMolecular weight:431.51Z-YVAD-CMK
CAS:Z-YVAD-CMK is an inhibitor of both caspase-1 and caspase-3, as referenced in [1].Formula:C30H37ClN4O9Purity:98%Color and Shape:SolidMolecular weight:633.09M190S
CAS:M109S is a novel small molecule that shields cells from mitochondria-dependent apoptosis, demonstrating effectiveness both in vitro and in vivo.Formula:C21H21N5O2Purity:98%Color and Shape:SolidMolecular weight:375.42
