Caspase
Caspase inhibitors are compounds that block the activity of caspases, a family of proteases that are central executors of apoptosis. Caspases cleave specific substrates within the cell to trigger the apoptotic process, leading to programmed cell death. Caspase inhibitors are used to study the mechanisms of apoptosis, as well as to prevent unwanted cell death in various research models. These inhibitors are also explored in therapeutic contexts to protect cells from apoptosis in diseases such as neurodegeneration. At CymitQuimica, we offer a wide range of high-quality caspase inhibitors to support your research in apoptosis, cell death, and related fields.
Found 154 products of "Caspase"
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Senkyunolide I
CAS:1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties.Formula:C12H16O4Purity:99.73% - 99.88%Color and Shape:SolidMolecular weight:224.25Ref: TM-T5S2076
1mg46.00€5mg84.00€10mg102.00€25mg152.00€50mg222.00€100mg340.00€200mg504.00€1mL*10mM (DMSO)94.00€Ossirene
CAS:Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.Formula:C2H4Cl3O2Te·H4NPurity:≥98%Color and Shape:SolidMolecular weight:312.05Ref: TM-T6761
2mg39.00€5mg58.00€10mg93.00€25mg138.00€50mg197.00€100mg294.00€200mg437.00€1mL*10mM (DMSO)66.00€Aristolactam I
CAS:Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway.Formula:C17H11NO4Purity:98.98% - 99.63%Color and Shape:SolidMolecular weight:293.27Ref: TM-T3S1227
1mg60.00€5mg140.00€10mg216.00€25mg369.00€50mg545.00€100mg775.00€1mL*10mM (DMSO)175.00€AVN-944
CAS:AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.
Formula:C25H27N5O5Purity:99.07% - ≥95%Color and Shape:SolidMolecular weight:477.51Emricasan
CAS:Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties.Formula:C26H27F4N3O7Purity:98.13% - 99%Color and Shape:SolidMolecular weight:569.5Ref: TM-T5S2358
1mg49.00€2mg69.00€5mg105.00€10mg137.00€25mg197.00€50mg295.00€100mg447.00€1mL*10mM (DMSO)116.00€PI-1840
CAS:PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.47Wedelolactone
CAS:Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.Formula:C16H10O7Purity:98.07% - 99.87%Color and Shape:SolidMolecular weight:314.25Ref: TM-T3384
1mg34.00€5mg71.00€10mg109.00€25mg175.00€50mg314.00€100mg414.00€500mg954.00€1mL*10mM (DMSO)50.00€Sesamolin
CAS:Sesamolin and sesamin guard nerves, reduce microglia damage by blocking p38 MAPK and caspase-3, and curb nitric oxide in stimulated cells.Formula:C20H18O7Purity:98.77% - 99.04%Color and Shape:SolidMolecular weight:370.35Ref: TM-T5S2283
1mg35.00€2mg50.00€5mg75.00€10mg120.00€25mg197.00€50mg294.00€100mg437.00€200mg622.00€1mL*10mM (DMSO)84.00€Ac-DEVD-CHO acetate
Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.Formula:C22H34N4O13Purity:98.54%Color and Shape:SolidMolecular weight:562.52BC-1471
CAS:BC-1471 is a STAMBP deubiquitinase inhibitor that blocks NALP7 inflammasome activity.Formula:C27H32N4O4SPurity:99.98%Color and Shape:SolidMolecular weight:508.63Ref: TM-T8553
1mg58.00€5mg128.00€10mg187.00€25mg323.00€50mg482.00€100mg658.00€200mg888.00€1mL*10mM (DMSO)144.00€Dehydrocorydaline nitrate
CAS:DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.Formula:C22H24N2O7Purity:99.79% - 99.92%Color and Shape:SolidMolecular weight:428.44Ref: TM-T2S2362
1mg89.00€5mg205.00€10mg334.00€25mg552.00€50mg782.00€100mg1,054.00€200mg1,414.00€1mL*10mM (DMSO)243.00€Dehydrotrametenolic acid
CAS:Dehydrotrametenolic acid (Dehydroeburicoic acid) induces necrotic cell death that involves Ca(2+) overload, mitochondrial dysfunction, and calpain activation inFormula:C31H48O3Purity:98%Color and Shape:SolidMolecular weight:468.71Limonin glucoside
CAS:Limonin glucoside: a citrus compound, blocks HIV/HTLV-1, triggers cancer cell death, kills Aedes larvae.Formula:C32H42O14Color and Shape:SolidMolecular weight:650.674CAY10406
CAS:CAY10406, a trifluoromethyl isatin sulfonamide, selectively targets and inhibits caspase-3 and -7, key in apoptosis, with no data on its inhibition potency.Formula:C27H23F3N2O5SColor and Shape:SolidMolecular weight:544.54AD-2646
CAS:AD-2646 has antidepressant activity and inhibits 2-deoxy-D-glucose (2-DG)-induced gastric acid secretion.Formula:C23H40N2O4Color and Shape:SolidMolecular weight:408.57VRT-043198
CAS:VRT-043198, a VX-765 metabolite, is a potent ICE/caspase-1 inhibitor, crossing the blood-brain barrier with K i of 0.8/0.6 nM.Formula:C22H29ClN4O6Color and Shape:SolidMolecular weight:480.94QM31
CAS:QM31 is a selective Apaf-1 inhibitor(inbitita formation of the apoptosome with IC50 of 7.9μM).Formula:C39H38Cl4N4O4Purity:98%Color and Shape:SolidMolecular weight:768.56N1,N11-Diethylnorspermine
CAS:DENSPM: potent anticancer, spurs polyamine breakdown, triggers cytochrome c release and caspase 3, kills GBM via SSAT & H2O2.Formula:C13H32N4Color and Shape:SolidMolecular weight:244.42ZYZ-488
CAS:ZYZ-488 is an Apoptosis protease activating factor-1 (Apaf-1) inhibitor, which suppresses the activation of procaspase-9 and procaspase-3.Formula:C20H29N3O11Purity:99.04%Color and Shape:SolidMolecular weight:487.46
